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|Application / Reactivity||Rat (Rattus)||Mouse (Murine)||Human|
|ELISA||11 Antibodies||11 Antibodies||40 Antibodies|
|Immunofluorescence (IF)||2 Antibodies||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies||11 Antibodies|
|Immunohistochemistry (IHC)||13 Antibodies||13 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||2 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||8 Antibodies||6 Antibodies|
|Western Blotting (WB)||29 Antibodies||32 Antibodies|
|Dot Blot (DB)||3 Antibodies|
|Enzyme Immunoassay (EIA)||6 Antibodies|
|Functional Studies (Func)||4 Antibodies|
|Antigen||Platelet-Derived Growth Factor beta Polypeptide (PDGFB) Antibodies|
|Epitope||AA 140-190 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This PDGFB antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|4 references available|
|Supplier||Log in to see|
Product Details anti-PDGFB AntibodyTarget Details PDGFB Application Details Handling References for anti-PDGFB Antibody (ABIN725990) Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human PDGF-B|
Target Details PDGFBProduct Details anti-PDGFB Antibody Application Details Handling References for anti-PDGFB Antibody (ABIN725990) Images back to top
|Alternative Name||PDGF-B (PDGFB Antibody Abstract)|
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
Subcellular location: Secreted
Synonyms: SIS, SSV, IBGC5, PDGF2, c-sis, PDGF-2, Platelet-derived growth factor subunit B, PDGF subunit B, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Proto-oncogene c-Sis, PDGFB
|Pathways||RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway|
Application DetailsProduct Details anti-PDGFB Antibody Target Details PDGFB Handling References for anti-PDGFB Antibody (ABIN725990) Images back to top
|Application Notes||WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)|
|Restrictions||For Research Use only|
HandlingProduct Details anti-PDGFB Antibody Target Details PDGFB Application Details References for anti-PDGFB Antibody (ABIN725990) Images back to top
|Buffer||Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
References for anti-PDGFB Antibody (ABIN725990)Product Details anti-PDGFB Antibody Target Details PDGFB Application Details Handling Images back to top
|Product cited in:||
He, Qi, Jia et al.: "Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p." in: Cancer letters, Vol. 368, Issue 1, pp. 115-25, 2015 (PubMed).
Hurley, Adams, Wang et al.: "Accelerated Fracture Healing in Transgenic Mice Overexpressing an Anabolic Isoform of Fibroblast Growth Factor 2." in: Journal of cellular biochemistry, 2015 (PubMed).
Morita, Furube, Mannari et al.: "Vascular endothelial growth factor-dependent angiogenesis and dynamic vascular plasticity in the sensory circumventricular organs of adult mouse brain." in: Cell and tissue research, 2015 (PubMed).
Lee, Zheng, Kang et al.: "Therapeutic efficacy of autologous platelet-rich plasma and polydeoxyribonucleotide on female pattern hair loss." in: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2015 (PubMed).
ImagesProduct Details anti-PDGFB Antibody Target Details PDGFB Application Details Handling References for anti-PDGFB Antibody (ABIN725990) back to top