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anti-Mouse (Murine) PDGFB antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PDGFB Antibody (supplied by: Log in to see )

Antigen
Platelet-Derived Growth Factor beta Polypeptide (PDGFB) Antibodies
  • c-sis
  • PDGF-2
  • PDGF-B
  • PDGF2
  • SIS
  • Sis
  • SSV
Reactivity
Human, Mouse (Murine), Rat (Rattus)
104
43
42
3
3
2
Host
Rabbit
92
6
6
5
Clonality
Polyclonal
Conjugate
This PDGFB antibody is un-conjugated
6
4
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
82
42
27
21
11
8
6
5
4
3
3
2
1
1
Supplier
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Catalog No. ABIN271781
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008917009 ABIN725990 IF (p) IHC (p) WB Rabbit IgG AA 140-190 Log in to see Polyclonal 4
0.0008917009 ABIN725999 IHC (p) WB HRP Rabbit IgG AA 140-190 Log in to see Polyclonal
0.0008917009 ABIN725992 IHC (p) WB Biotin Rabbit IgG AA 140-190 Log in to see Polyclonal
0.0008917009 ABIN1737934 IHC (p) Goat C-Term Log in to see Polyclonal

Top referenced anti-PDGFB antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-PDGFB Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 79 Antibodies 31 Antibodies 28 Antibodies
Neutralization (Neut) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 23 Antibodies 7 Antibodies 5 Antibodies
Immunohistochemistry (IHC) 25 Antibodies 12 Antibodies 12 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies 11 Antibodies
Immunofluorescence (IF) 8 Antibodies 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 3 Antibodies

General

Antigen Platelet-Derived Growth Factor beta Polypeptide (PDGFB) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(104), (43), (42), (3), (3), (2)
Host Rabbit
(92), (6), (6), (5)
Clonality
Polyclonal
Conjugate This PDGFB antibody is un-conjugated
(6), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(82), (42), (27), (21), (11), (8), (6), (5), (4), (3), (3), (2), (1), (1)
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Product Details anti-PDGFB Antibody

Target Details PDGFB Application Details Handling Images
Specificity This antibody detects endogenous levels of PDGFB protein. (region surrounding Leu48)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity Chromatography using epitope-specific immunogen.

Target Details PDGFB

Product Details anti-PDGFB Antibody Application Details Handling Images back to top
Antigen
Alternative Name PDGFB (PDGFB Antibody Abstract)
Background PDGF is a mitogen for mesenchyme- and glia-derived cells. It consists of two disulfide-bonded polypeptide chains, A and B, and occurs as three isoforms, PDGF AA, PDGF AB and PDGF BB. The three isoforms bind with different affinities to two receptor types, α and β, which are structurally related and endowed with protein-tyrosine kinase domains. Ligand binding induces activation of the receptor kinases by formation of receptor dimers, the A subunit of PDGF binds only to α receptors with high affinity, whereas the B subunit can bind to both α and β receptors. Evidence suggests that PDGF may function as a neurotrophic factor. The fact that receptors for PDGF-A are expressed in oligodendrocyte progenitor cells whereas receptors for PDGF-B are expressed on neurons suggests that the different isoforms of PDGF may regulate growth and differentiation of different cell types in the developing central nervous system by paracrine and autocrine routes.Synonyms: Becaplermin, PDGF B, PDGF beta, PDGF subunit B, PDGF-2, PDGF-B, PDGF2, Platelet-derived growth factor B chain, Platelet-derived growth factor beta, Platelet-derived growth factor subunit B, SIS, c-Sis
Molecular Weight approx. 27 kDa
Gene ID 5155
NCBI Accession NP_002599
UniProt P01127
Research Area Cytokines, Receptors, Inflammation
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-PDGFB Antibody Target Details PDGFB Handling Images back to top
Application Notes ELISA: 1/10000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PDGFB Antibody Target Details PDGFB Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid Repeated freeze/thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-PDGFB Antibody Target Details PDGFB Application Details Handling back to top
Supplier Images
 image for anti-PDGFB antibody (Platelet-Derived Growth Factor beta Polypeptide) (ABIN271781) anti-Platelet-Derived Growth Factor beta Polypeptide (PDGFB) antibody
 image for anti-PDGFB antibody (Platelet-Derived Growth Factor beta Polypeptide) (ABIN271781) anti-Platelet-Derived Growth Factor beta Polypeptide (PDGFB) antibody (Image 2)