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anti-Human PDGFBB antibody for Functional Studies

Recommended PDGFBB Antibody (supplied by: Log in to see )

Antigen
Platelet Derived Growth Factor BB (PDGFBB) Antibodies
  • PDGF-2
  • PDGF2
  • SIS
  • SSV
  • c-sis
  • platelet-derived growth factor beta polypeptide
  • PDGFB
Reactivity
Human
54
17
16
3
3
1
1
1
1
1
Host
Rabbit
62
4
2
1
Clonality
Polyclonal
Conjugate
This PDGFBB antibody is un-conjugated
8
5
2
2
2
2
Application
Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
64
44
18
9
6
5
3
3
2
2
2
1
1
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Catalog No. ABIN205671
$ 654.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN205942 Func ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN640559 Func ELISA WB Rabbit IgG Log in to see

Similar anti-PDGFBB Antibodies

Application / Reactivity Human
Blocking Antibody (Inhibition) 2 Antibodies
ELISA 35 Antibodies
Functional Studies (Func) 3 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunohistochemistry (IHC) 12 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 7 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Neutralization (Neut) 9 Antibodies
Western Blotting (WB) 50 Antibodies

General

Antigen Platelet Derived Growth Factor BB (PDGFBB) Antibodies
Reactivity Human
(54), (17), (16), (3), (3), (1), (1), (1), (1), (1)
Host Rabbit
(62), (4), (2), (1)
Clonality
Polyclonal
Conjugate This PDGFBB antibody is un-conjugated
(8), (5), (2), (2), (2), (2)
Application Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(64), (44), (18), (9), (6), (5), (3), (3), (2), (2), (2), (1), (1)
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Product Details anti-PDGFBB Antibody

Target Details PDGFBB Application Details Handling Images
Specificity Human PDGF-BB (Platelet derived growth factor B chain), a disulphide-linked beta-chain homodimer and member of the PDGF family, released from platelet alpha-granules following trauma/platelet activation. Naturally occurring active forms of PDGF exist as dimers of two alpha chains (AA), two beta chains (BB), or a combination of both chains (AB), all of which signal through the high-affinity PDGF-Ralpha receptor, and the latter two of which can also signal through the PDGF-Rbeta receptor. PDGFs are potent mitogens for a variety of cells including those of the connective tissue, bone and cartilage, blood and smooth muscle cells, and are involved in several biological processes including chemotaxis, hyperplasia and embryonic neurogenesis. The expression of PDGF-BB is associated with autocrine growth stimulation and the formation of various tumor types, with several studies focusing on dermatofibrosarcoma protuberans (DP), an infiltrating skin tumor arising from a translocation occurring between chromosome 22 (the location of the PDGFB gene) and chromosome 17 (the location of the COL1A1 gene), which results in the generation of the COL1A1-PDGFB chimeric protein.
Purification Affinity purified
Immunogen Recombinant human PDGF BB.

Type of Immunogen: Recombinant protein
Isotype IgG

Target Details PDGFBB

Product Details anti-PDGFBB Antibody Application Details Handling Images back to top
Antigen
Alternative Name PDGF-BB (PDGFBB Antibody Abstract)
Background Name/Gene ID: PDGFB
Family: PDGF

Synonyms: PDGFB, Becaplermin, PDGF-BB, PDGF-b, SSV, PDGF subunit B, PDGF-2, PDGF2, Proto-oncogene c-Sis, SIS, C-sis, PDGF, B chain
Gene ID 5155
UniProt P01127
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process

Application Details

Product Details anti-PDGFBB Antibody Target Details PDGFBB Handling Images back to top
Application Notes Approved: ELISA (1:2000 - 1:8000), Func, IHC-P, WB

Usage: This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or proteinase K.
Restrictions For Research Use only

Handling

Product Details anti-PDGFBB Antibody Target Details PDGFBB Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer PBS, pH 7.4, 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Images

Product Details anti-PDGFBB Antibody Target Details PDGFBB Application Details Handling back to top
Supplier Images
 image for anti-PDGFBB antibody (Platelet Derived Growth Factor BB) (ABIN205671) anti-Platelet Derived Growth Factor BB (PDGFBB) antibody