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Browse our anti-PDGFC (PDGFC) Antibodies

Full name:
anti-Platelet-Derived Growth Factor C Antibodies (PDGFC)
On www.antibodies-online.com are 71 Platelet-Derived Growth Factor C (PDGFC) Antibodies from 17 different suppliers available. Additionally we are shipping PDGFC Kits (50) and PDGFC Proteins (18) and many more products for this protein. A total of 146 PDGFC products are currently listed.
Synonyms:
1110064L01Rik, AI647969, FALLOTEIN, PDGF-C, SCDGF
list all antibodies Gene Name GeneID UniProt
PDGFC 79429 Q9EQX6
PDGFC 56034 Q9NRA1
PDGFC 54635 Q8CI19

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Most Popular Reactivities for anti-PDGFC (PDGFC) Antibodies

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anti-Rat (Rattus) PDGFC Antibodies:

anti-Human PDGFC Antibodies:

anti-Mouse (Murine) PDGFC Antibodies:

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Top referenced anti-PDGFC Antibodies

  1. Human Polyclonal PDGFC Primary Antibody for IHC (p), WB - ABIN650654 : Zwerner, May: Dominant negative PDGF-C inhibits growth of Ewing family tumor cell lines. in Oncogene 2002 (PubMed)

  2. Human Polyclonal PDGFC Primary Antibody for IF (p), IHC (p) - ABIN714566 : Hurley, Adams, Wang, Jiang, Meo Burt, Du, Xiao: Accelerated Fracture Healing in Transgenic Mice Overexpressing an Anabolic Isoform of Fibroblast Growth Factor 2. in Journal of cellular biochemistry 2015 (PubMed)

More Antibodies against PDGFC Interaction Partners

Human Platelet-Derived Growth Factor C (PDGFC) interaction partners

  1. High glucose-mediated induction of PDGF-C via ChREBP (show MLXIPL Antibodies) in mesangial cells contributes to the development of glomerular mesangial expansion in diabetes.

  2. PDGF-C up-regulation was mediated by the human embryonic lethal abnormal vision-like protein HuR (show ELAVL1 Antibodies), which stabilizes the PDGF-C transcript by binding to two predicted AU-rich elements (AREs) in the 3'-untranslated region (3'-UTR (show UTS2R Antibodies)).

  3. Concomitant upregulation of PDGF-C with VEGF in Glioblastoma tumor cells.

  4. The results indicate that PDGF-C upregulation and calpain-3 (show CAPN3 Antibodies) downregulation are involved in the aggressiveness of malignant melanoma and suggest that modulators of these proteins

  5. Platelet-derived growth factor-C (PDGF-C) induces anti-apoptotic effects on macrophages through Akt (show AKT1 Antibodies) and Bad phosphorylation.

  6. Data indicate uPA (plau (show PLAU Antibodies)) and PAI1 (Serpine1 (show SERPINE1 Antibodies)) were up-regulated in human PDGF-C Tg mice, suggesting that uPA (show PRAP1 Antibodies) could be compensating for the loss of tissue-type plasminogen activator (tPA (show PLAT Antibodies)) activity in PDGF-C Tg; tpa (show PLAT Antibodies) KO mice.

  7. High PDGF-C expression induces progressive fibrosis, chronic inflammation, neoangiogenesis and sinusoidal congestion resulting in hepatocellular carcinoma.

  8. PDGF-C is both angiogenic and a neuronal survival factor, and it is an important component of neurovascular crosstalk. [Review]

  9. Results indicate that the alpha-SMA (show SMN1 Antibodies) inducing effect of M2 macrophages is in part mediated by secretion of PGDF-CC.

  10. Single nucleotide polymorphisms in the PDGF-C gene are linked to the development of oral clefts.

Mouse (Murine) Platelet-Derived Growth Factor C (PDGFC) interaction partners

  1. High glucose-mediated induction of PDGF-C via ChREBP (show MLXIPL Antibodies) in mesangial cells contributes to the development of glomerular mesangial expansion in diabetes.

  2. PDGF (show PDGFA Antibodies)-CC neutralization or deficiency was not associated with preservation or accelerated loss of peritubular capillaries, suggesting no significant pro-angiogenic effects of PDGF (show PDGFA Antibodies)-CC during renal fibrosis

  3. heme oxygenase-1 (HMOX1 (show HMOX1 Antibodies)) activity is critically required for the vascular protective/survival effect of PDGF (show PDGFA Antibodies)-CC.

  4. Studied survival and antiapoptotic effects of PDGF-C on focal retinal lesions in Ccl2 (show CCL2 Antibodies)(-/-)/Cx3cr1 (show CX3CR1 Antibodies)(-/-) on C57BL/6N [Crb1 (show CRB1 Antibodies)(rd8)] (DKO rd8) background mice, a model for progressive and focal retinal degeneration.

  5. loss of FREM1 (show FREM1 Antibodies) function promotes epidermal blistering in Fraser syndrome as a consequence of reduced PDGFC activity, in addition to its stabilising role in the basement membrane

  6. Study indicates the role for PDGF-C as a critical regulator of impaired angiogenesis of diabetes.

  7. High PDGF-C expression induces progressive fibrosis, chronic inflammation, neoangiogenesis and sinusoidal congestion resulting in hepatocellular carcinoma.

  8. PDGF-C promotes tumor growth via a growth promoting effect on hepatic stellate cells that is dependent on the presence of functional PAK-2 (show PAK2 Antibodies)

  9. Data identified PDGF (show PDGFA Antibodies)-CC as an important candidate target gene for antiangiogenic therapy, and PDGF (show PDGFA Antibodies)-CC inhibition may be of therapeutic value in treating neovascular diseases.

  10. PDGF (show PDGFA Antibodies)-CC is critically required for neuronal survival in both brain and retina. Its neuroprotective effect of PDGF (show PDGFA Antibodies)-CC is achieved by regulating GSK3beta (show GSK3b Antibodies) phosphorylation and expression.

PDGFC Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with PDGFC

  • platelet derived growth factor C (PDGFC) antibody
  • platelet derived growth factor C (Pdgfc) antibody
  • platelet-derived growth factor C-like (LOC100350272) antibody
  • platelet-derived growth factor C-like (LOC100515267) antibody
  • platelet-derived growth factor, C polypeptide (Pdgfc) antibody
  • 1110064L01Rik antibody
  • AI647969 antibody
  • FALLOTEIN antibody
  • PDGF-C antibody
  • SCDGF antibody

Protein level used designations for PDGFC

platelet-derived growth factor C , PDGF-C , VEGF-E , fallotein , platelet-derived growth factor, C polypeptide , rScdfg , spinal cord-derived growth factor , secretory growth factor-like protein , SCDGF

GENE ID SPECIES
736477 Pan troglodytes
79429 Rattus norvegicus
56034 Homo sapiens
482666 Canis lupus familiaris
613787 Bos taurus
100722571 Cavia porcellus
395469 Gallus gallus
101112600 Ovis aries
100350272 Oryctolagus cuniculus
100515267 Sus scrofa
54635 Mus musculus
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