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anti-Human PDGFRA antibody for Functional Studies

Recommended PDGFRA Antibody (supplied by: Log in to see )

Antigen
Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies
  • AI115593
  • CD140a
  • Pdgfr-2
  • APDGFR
  • PDGFACE
  • CD140A
  • PDGFR-2
  • PDGFR2
  • RHEPDGFRA
  • PDGFR
  • PDGFR-A
  • platelet-derived growth factor receptor, alpha polypeptide
  • platelet derived growth factor receptor, alpha polypeptide
  • platelet-derived growth factor receptor alpha
  • PDGFRA
  • LOC100218386
  • Pdgfra
  • pdgfra
  • LOC100343006
Reactivity
Human
441
204
134
4
3
3
3
3
2
1
1
1
1
1
1
Host
Mouse
346
118
35
4
1
Clonality
Monoclonal
Conjugate
This PDGFRA antibody is un-conjugated
32
29
23
23
20
14
10
9
6
6
5
5
5
5
5
5
4
4
3
3
3
3
3
3
2
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunoprecipitation (IP)
290
198
170
118
78
57
50
44
16
14
11
9
3
3
1
1
1
1
1
1
Options
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Catalog No. ABIN2688972
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN260348 Func IHC (p) IHC ELISA WB Mouse IgG1 Log in to see 35248 (57-20)
1 ABIN640562 Func IHC (p) ELISA WB Mouse Log in to see

Top referenced anti-PDGFRA antibody for Functional Studies

Similar anti-PDGFRA Antibodies

Application / Reactivity Human
Cytometry by Time of Flight (CyTOF) 1 Antibodies
Dot Blot (DB) 14 Antibodies
ELISA 179 Antibodies
Enzyme Immunoassay (EIA) 9 Antibodies
Flow Cytometry (FACS) 85 Antibodies
Functional Studies (Func) 3 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 42 Antibodies
Immunofluorescence (IF) 50 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 57 Antibodies
Immunohistochemistry (IHC) 150 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 77 Antibodies
Immunoprecipitation (IP) 12 Antibodies
In vitro Assay (in vitro) 1 Antibodies
Neutralization (Neut) 1 Antibodies

General

Antigen Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies
Reactivity Human
(441), (204), (134), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(346), (118), (35), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This PDGFRA antibody is un-conjugated
(32), (29), (23), (23), (20), (14), (10), (9), (6), (6), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Flow Cytometry (FACS), Immunoprecipitation (IP)
(290), (198), (170), (118), (78), (57), (50), (44), (16), (14), (11), (9), (3), (3), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-PDGFRA Antibody

Target Details PDGFRA Application Details Handling References for anti-PDGFRA Antibody (ABIN2688972) Images
Brand BD Pharmingen™
Characteristics Reacts with platelet derived growth factor (PDGF) receptor α, CD140a, a 170 kD single transmembrane glycoprotein expressed on fibroblasts, smooth muscle cells, glial cells and chondrocytes. PDGF receptors, α and β, are single glycoproteins with intracellular tyrosine kinase domain. They are structurally similar to M-CSF receptor and CD117 (c-kit). Their ligand, PDGF, is a mitogen for connective tissue cells and glial cells. PDGF plays a role in wound healing and it also acts as a chemoattractant for fibroblasts, smooth muscle cells, glial cells, monocytes and neutrophils. Functional PDGF is secreted as a dimer, disulfide linked, A and B chains (PDGFAA, PDGF-BB or PDGF-AB). Binding of divalent PDGF induces receptor dimerization with three possible forms: αα, αβ, ββ. The PDGF receptor α-subunit binds both PDGF A and B chains, whereas the receptor β-subunit binds only PDGF B chains. Both receptor subunits can stimulate mitogenic responses, only the β subunit can induce chemotaxis. αR1 is specific for αPDGFR and does not cross react with βPDGFR. It immunoprecipitates human, monkey, rabbit, pig, dog and cat αPDGFR. It does not recognize hamster, rat or mouse αPDGFR. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of MG-63 (osteosarcoma cell line) cells analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD140a - Purified - Clone αR1 (also known as Alpha-R1) - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Clone AlphaR1
Isotype IgG2a, kappa

Target Details PDGFRA

Product Details anti-PDGFRA Antibody Application Details Handling References for anti-PDGFRA Antibody (ABIN2688972) Images back to top
Antigen
Alternative Name CD140a (PDGFRA Antibody Abstract)
Background Synonyms: PDGF receptor α chain
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-PDGFRA Antibody Target Details PDGFRA Handling References for anti-PDGFRA Antibody (ABIN2688972) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details References for anti-PDGFRA Antibody (ABIN2688972) Images back to top
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.

References for anti-PDGFRA Antibody (ABIN2688972)

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details Handling Images back to top
Product cited in:

Bazenet, Kazlauskas: "The PDGF receptor alpha subunit activates p21ras and triggers DNA synthesis without interacting with rasGAP." in: Oncogene, Vol. 9, Issue 2, pp. 517-25, 1994