You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human PDGFRA antibody for Immunocytochemistry

Recommended PDGFRA Antibody (supplied by: Log in to see )

Antigen
Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies
  • AI115593
  • APDGFR
  • CD140A
  • CD140a
  • PDGFACE
  • PDGFR
  • PDGFR-2
  • Pdgfr-2
  • PDGFR-A
  • PDGFR2
  • RHEPDGFRA
Reactivity
Human
375
174
124
4
3
3
3
3
2
1
1
1
1
1
1
Host
Mouse
330
64
24
1
1
Clonality
Monoclonal
Conjugate
This PDGFRA antibody is un-conjugated
29
24
24
22
19
14
5
5
5
5
5
5
5
5
5
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS)
248
173
143
70
57
56
35
20
14
10
9
5
4
3
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Catalog No. ABIN457411
$ 254.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010161072 ABIN446762 ICC IF IHC (p) IHC WB Rabbit Ser1057 Log in to see Polyclonal
0.0010161072 ABIN1953246 ICC IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG Tyr754 Log in to see Polyclonal
0.0010161072 ABIN1954118 ICC IHC ELISA WB APC Rabbit IgG Tyr754 Log in to see Polyclonal
0.0010161072 ABIN1956548 ICC IHC ELISA WB FITC Rabbit IgG Tyr754 Log in to see Polyclonal
0.0010161072 ABIN1955363 ICC IHC ELISA WB Biotin Rabbit IgG Tyr754 Log in to see Polyclonal
0.0010161072 ABIN1958891 ICC IHC ELISA WB PE Rabbit IgG Tyr754 Log in to see Polyclonal
0.0010161072 ABIN490145 ICC FACS Mouse IgG1 Log in to see 16A1
0.0010161072 ABIN1957739 ICC IHC ELISA WB HRP Rabbit IgG Tyr754 Log in to see Polyclonal
0.0010161072 ABIN2884200 ICC IHC ELISA Rabbit IgG AA 731-780 Log in to see Polyclonal
0.0010161072 ABIN2626661 ICC Rabbit C-Term Log in to see Polyclonal
0.0010161072 ABIN1869734 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
0.0010161072 ABIN1848738 ICC IF IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
0.0010161072 ABIN1844663 ICC IF IHC WB Rabbit Log in to see Polyclonal
0.0010161072 ABIN3036687 ICC FACS IF Mouse IgG1 Log in to see
0.0010161072 ABIN3036690 ICC FACS IF Biotin Mouse IgG1 Log in to see
0.0010161072 ABIN3036688 ICC FACS IF PE Mouse IgG1 Log in to see
0.0010161072 ABIN3036691 ICC FACS IF FITC Mouse IgG1 Log in to see
0.0010161072 ABIN3036689 ICC FACS IF APC Mouse IgG1 Log in to see
0.0010161072 ABIN2857324 ICC IF IHC WB Rabbit Log in to see Polyclonal

Top referenced anti-PDGFRA antibody for Immunocytochemistry

Similar anti-PDGFRA Antibodies

Application / Reactivity Human
Dot Blot (DB) 14 Antibodies
ELISA 155 Antibodies
Enzyme Immunoassay (EIA) 9 Antibodies
Flow Cytometry (FACS) 36 Antibodies
Functional Studies (Func) 3 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 20 Antibodies
Immunofluorescence (IF) 36 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 57 Antibodies
Immunohistochemistry (IHC) 140 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 73 Antibodies
Immunoprecipitation (IP) 10 Antibodies
Neutralization (Neut) 1 Antibodies
Proximity Ligation Assay (PLA) 3 Antibodies

General

Antigen Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies
Reactivity Human
(375), (174), (124), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(330), (64), (24), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This PDGFRA antibody is un-conjugated
(29), (24), (24), (22), (19), (14), (5), (5), (5), (5), (5), (5), (5), (5), (5), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS)
(248), (173), (143), (70), (57), (56), (35), (20), (14), (10), (9), (5), (4), (3), (1), (1), (1), (1)
Pubmed 4 references available
Supplier Log in to see

Product Details anti-PDGFRA Antibody

Target Details PDGFRA Application Details Handling References for anti-PDGFRA Antibody (ABIN457411) Images
Specificity The mouse monoclonal antibody 16A1 recognizes CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours. HLDA VI., WS Code E022
Purification Purified from ascites by protein-A affinity chromatography.
Purity > 95 % (by SDS-PAGE)
Immunogen CD140a-transfected NIH 3T3 cells
Clone 16A1
Isotype IgG1

Target Details PDGFRA

Product Details anti-PDGFRA Antibody Application Details Handling References for anti-PDGFRA Antibody (ABIN457411) Images back to top
Antigen
Alternative Name PDGFRA (PDGFRA Antibody Abstract)
Background CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-PDGFRA Antibody Target Details PDGFRA Handling References for anti-PDGFRA Antibody (ABIN457411) Images back to top
Application Notes Flow Cytometry: Recommended dilution: 2 µg/mL

Working concentrations should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details References for anti-PDGFRA Antibody (ABIN457411) Images back to top
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8 °C. Do not use after expiration date stamped on vial label.

References for anti-PDGFRA Antibody (ABIN457411)

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details Handling Images back to top
Background publications

Faraone, Aguzzi, Toietta, Facchiano, Facchiano, Magenta, Martelli, Truffa, Cesareo, Ribatti, Capogrossi, Facchiano: "Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo." in: Neoplasia (New York, N.Y.), Vol. 11, Issue 8, pp. 732-42, 2009

Schmahl, Rizzolo, Soriano: "The PDGF signaling pathway controls multiple steroid-producing lineages." in: Genes & development, Vol. 22, Issue 23, pp. 3255-67, 2008

French, Creemers, Tallquist: "Platelet-derived growth factor receptors direct vascular development independent of vascular smooth muscle cell function." in: Molecular and cellular biology, Vol. 28, Issue 18, pp. 5646-57, 2008

Andrae, Gallini, Betsholtz: "Role of platelet-derived growth factors in physiology and medicine." in: Genes & development, Vol. 22, Issue 10, pp. 1276-312, 2008