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anti-Human PDGFRA antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended PDGFRA Antibody (supplied by: Log in to see )

Antigen
Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies
  • AI115593
  • CD140a
  • Pdgfr-2
  • APDGFR
  • PDGFACE
  • CD140A
  • PDGFR-2
  • PDGFR2
  • RHEPDGFRA
  • PDGFR
  • PDGFR-A
  • platelet-derived growth factor receptor, alpha polypeptide
  • platelet derived growth factor receptor, alpha polypeptide
  • platelet-derived growth factor receptor alpha
  • PDGFRA
  • LOC100218386
  • Pdgfra
  • pdgfra
  • LOC100343006
Epitope
AA 1020-1070
51
19
19
18
18
18
17
15
15
15
14
14
11
11
11
11
10
10
7
6
6
6
5
5
5
5
5
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
458
255
158
7
6
6
6
6
4
3
3
3
2
2
1
1
1
1
Host
Rabbit
352
131
49
4
1
Clonality
Polyclonal
Conjugate
This PDGFRA antibody is un-conjugated
34
30
26
25
21
14
12
11
7
7
7
6
5
5
5
5
5
5
5
5
4
4
4
4
4
3
2
2
2
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
308
192
179
130
96
66
49
41
15
14
12
9
9
4
3
2
1
1
1
1
1
Options
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Catalog No. ABIN726620
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN710981 IF (p) IHC (p) WB Rabbit IgG pTyr762 Log in to see Polyclonal
1 ABIN2814977 IF (p) Alexa Fluor 594 Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN910516 IF (p) Alexa Fluor 350 Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN910517 IF (p) Alexa Fluor 555 Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN910518 IF (p) Alexa Fluor 647 Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN910515 IF (p) Alexa Fluor 488 Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN726624 IF (p) Cy5 Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN726626 IF (p) Cy7 Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN726623 IF (p) Cy3 Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN726627 IF (p) FITC Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN726625 IF (p) Cy5.5 Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN2805204 IF (p) Alexa Fluor 594 Rabbit IgG pTyr988 Log in to see Polyclonal
1 ABIN2805207 IF (p) Alexa Fluor 594 Rabbit IgG pTyr579 Log in to see Polyclonal
1 ABIN2805206 IF (p) Alexa Fluor 594 Rabbit IgG pTyr857 Log in to see Polyclonal
1 ABIN2805202 IF (p) Alexa Fluor 594 Rabbit IgG pTyr1018 Log in to see Polyclonal
1 ABIN744536 IF (p) Cy3 Rabbit IgG pTyr1018 Log in to see Polyclonal
1 ABIN744537 IF (p) Cy5 Rabbit IgG pTyr1018 Log in to see Polyclonal
1 ABIN744539 IF (p) Cy7 Rabbit IgG pTyr1018 Log in to see Polyclonal
1 ABIN744538 IF (p) Cy5.5 Rabbit IgG pTyr1018 Log in to see Polyclonal
1 ABIN744567 IF (p) Cy5 Rabbit IgG pTyr857 Log in to see Polyclonal

Top referenced anti-PDGFRA antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-PDGFRA Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 37 Antibodies 64 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 5 Antibodies 7 Antibodies
Immunofluorescence (IF) 16 Antibodies 17 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 67 Antibodies
Immunohistochemistry (IHC) 39 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 40 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Western Blotting (WB) 74 Antibodies
Flow Cytometry (FACS) 41 Antibodies
Functional Studies (Func) 1 Antibodies

General

Antigen Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies
Epitope AA 1020-1070
(51), (19), (19), (18), (18), (18), (17), (15), (15), (15), (14), (14), (11), (11), (11), (11), (10), (10), (7), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(458), (255), (158), (7), (6), (6), (6), (6), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Host Rabbit
(352), (131), (49), (4), (1)
Clonality
Polyclonal
Conjugate This PDGFRA antibody is un-conjugated
(34), (30), (26), (25), (21), (14), (12), (11), (7), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(308), (192), (179), (130), (96), (66), (49), (41), (15), (14), (12), (9), (9), (4), (3), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-PDGFRA Antibody

Target Details PDGFRA Application Details Handling References for anti-PDGFRA Antibody (ABIN726620) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human PDGF-R-A
Isotype IgG

Target Details PDGFRA

Product Details anti-PDGFRA Antibody Application Details Handling References for anti-PDGFRA Antibody (ABIN726620) Images back to top
Antigen
Alternative Name PDGFRA (PDGFRA Antibody Abstract)
Background

Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. Plays a role in cell migration and chemotaxis in wound healing. Plays a role in platelet activation, secretion of agonists from platelet granules, and in thrombin-induced platelet aggregation. Binding of its cognate ligands - homodimeric PDGFA, homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFC -leads to the activation of several signaling cascades, the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PIK3R1, PLCG1, and PTPN11. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, mobilization of cytosolic Ca(2+) and the activation of protein kinase C. Phosphorylates PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and thereby mediates activation of the AKT1 signaling pathway. Mediates activation of HRAS and of the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3 and STAT5A and/or STAT5B. Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalization of the activated receptor.

Subcellular location: Cytoplasm


Synonyms: CD140A, PDGFR2, PDGFR-2, RHEPDGFRA, Platelet-derived growth factor receptor alpha, PDGF-R-alpha, PDGFR-alpha, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a antigen, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, PDGFRA
Gene ID 5156
UniProt P16234
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling

Application Details

Product Details anti-PDGFRA Antibody Target Details PDGFRA Handling References for anti-PDGFRA Antibody (ABIN726620) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details References for anti-PDGFRA Antibody (ABIN726620) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-PDGFRA Antibody (ABIN726620)

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details Handling Images back to top
Product cited in:

Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: "The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious." in: International journal of clinical and experimental pathology, Vol. 8, Issue 2, pp. 1525-34, 2015

Images

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details Handling References for anti-PDGFRA Antibody (ABIN726620) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-PDGFRA antibody (Platelet-Derived Growth Factor Receptor, alpha Polypeptide) (AA 1020-1070) (ABIN726620) Formalin-fixed and paraffin embedded: rat colitis tissue labeled with Anti-PDGFRA Pol...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-PDGFRA antibody (Platelet-Derived Growth Factor Receptor, alpha Polypeptide) (AA 1020-1070) (ABIN726620) Formalin-fixed and paraffin embedded: rat colitis tissue labeled with Anti-PDGFRA Pol...