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anti-Mouse (Murine) PDGFRA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PDGFRA Antibody (supplied by: Log in to see )

Antigen
Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies
  • AI115593
  • CD140a
  • Pdgfr-2
  • APDGFR
  • PDGFACE
  • CD140A
  • PDGFR-2
  • PDGFR2
  • RHEPDGFRA
  • PDGFR
  • PDGFR-A
  • platelet-derived growth factor receptor, alpha polypeptide
  • platelet derived growth factor receptor, alpha polypeptide
  • platelet-derived growth factor receptor alpha
  • PDGFRA
  • LOC100218386
  • Pdgfra
  • pdgfra
  • LOC100343006
Epitope
AA 1020-1070
51
19
19
18
18
18
17
15
15
15
14
14
12
11
11
10
9
7
6
5
5
5
5
5
5
4
4
4
4
4
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
450
257
158
6
6
6
6
5
3
3
3
2
2
1
1
1
1
Host
Rabbit
352
121
49
4
1
Clonality
Polyclonal
Conjugate
This PDGFRA antibody is un-conjugated
34
29
25
24
21
14
11
10
6
6
6
5
5
5
5
5
5
5
5
5
4
4
4
4
4
3
2
2
2
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
308
197
187
119
93
66
52
40
15
14
12
9
9
4
3
2
1
1
1
1
1
Options
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Catalog No. ABIN726620
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.931439 ABIN446762 ICC IF IHC (p) IHC WB Rabbit Log in to see Polyclonal 2
12.931439 ABIN784591 IHC (p) IP WB Rabbit IgG AA 1035-1053 Log in to see Polyclonal
12.931439 ABIN498160 IF IHC (p) WB Rabbit Log in to see Polyclonal
12.931439 ABIN258869 IHC (p) IHC WB Rat IgG2 Log in to see RM0004-3G28
12.931439 ABIN337400 IHC (p) ELISA Rabbit IgG C-Term Log in to see Polyclonal
12.931439 ABIN461761 IHC (p) Rabbit C-Term Log in to see Polyclonal
12.931439 ABIN710981 IF (p) IHC (p) WB Rabbit IgG pTyr762 Log in to see Polyclonal
1 ABIN392022 FACS IHC (p) WB Rabbit Ig AA 1048-1077, C-Term Log in to see Polyclonal 1
1 ABIN372491 EIA IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN372897 EIA IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN3043897 IHC (p) WB Rabbit IgG AA 968-1002, C-Term Log in to see Polyclonal
1 ABIN3187792 ELISA IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN790499 IHC (p) IP WB Rabbit IgG AA 1035-1053 Log in to see Polyclonal
1 ABIN1492007 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN2888854 IHC (p) ELISA Rabbit IgG AA 721-770 Log in to see Polyclonal
1 ABIN2889249 IF IHC (p) ELISA WB Rabbit IgG AA 1031-1080 Log in to see Polyclonal
1 ABIN726629 IHC (p) WB HRP Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN2626645 IHC (p) WB Rabbit IgG AA 1030-1043 Log in to see Polyclonal
1 ABIN325544 FACS IF IHC (p) IP WB Rabbit IgG C-Term Log in to see
1 ABIN4344481 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal

Top referenced anti-PDGFRA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-PDGFRA Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 39 Antibodies 68 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 5 Antibodies 7 Antibodies
Immunofluorescence (IF) 18 Antibodies 19 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 67 Antibodies
Immunohistochemistry (IHC) 42 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 41 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Western Blotting (WB) 74 Antibodies
Flow Cytometry (FACS) 41 Antibodies
Functional Studies (Func) 1 Antibodies

General

Antigen Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies
Epitope AA 1020-1070
(51), (19), (19), (18), (18), (18), (17), (15), (15), (15), (14), (14), (12), (11), (11), (10), (9), (7), (6), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(450), (257), (158), (6), (6), (6), (6), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Host Rabbit
(352), (121), (49), (4), (1)
Clonality
Polyclonal
Conjugate This PDGFRA antibody is un-conjugated
(34), (29), (25), (24), (21), (14), (11), (10), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(308), (197), (187), (119), (93), (66), (52), (40), (15), (14), (12), (9), (9), (4), (3), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-PDGFRA Antibody

Target Details PDGFRA Application Details Handling References for anti-PDGFRA Antibody (ABIN726620) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human PDGF-R-A
Isotype IgG

Target Details PDGFRA

Product Details anti-PDGFRA Antibody Application Details Handling References for anti-PDGFRA Antibody (ABIN726620) Images back to top
Antigen
Alternative Name PDGFRA (PDGFRA Antibody Abstract)
Background

Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. Plays a role in cell migration and chemotaxis in wound healing. Plays a role in platelet activation, secretion of agonists from platelet granules, and in thrombin-induced platelet aggregation. Binding of its cognate ligands - homodimeric PDGFA, homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFC -leads to the activation of several signaling cascades, the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PIK3R1, PLCG1, and PTPN11. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, mobilization of cytosolic Ca(2+) and the activation of protein kinase C. Phosphorylates PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and thereby mediates activation of the AKT1 signaling pathway. Mediates activation of HRAS and of the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3 and STAT5A and/or STAT5B. Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalization of the activated receptor.

Subcellular location: Cytoplasm


Synonyms: CD140A, PDGFR2, PDGFR-2, RHEPDGFRA, Platelet-derived growth factor receptor alpha, PDGF-R-alpha, PDGFR-alpha, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a antigen, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, PDGFRA
Gene ID 5156
UniProt P16234
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-PDGFRA Antibody Target Details PDGFRA Handling References for anti-PDGFRA Antibody (ABIN726620) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details References for anti-PDGFRA Antibody (ABIN726620) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-PDGFRA Antibody (ABIN726620)

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details Handling Images back to top
Product cited in:

Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: "The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious." in: International journal of clinical and experimental pathology, Vol. 8, Issue 2, pp. 1525-34, 2015

Images

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details Handling References for anti-PDGFRA Antibody (ABIN726620) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-PDGFRA antibody (Platelet-Derived Growth Factor Receptor, alpha Polypeptide) (AA 1020-1070) (ABIN726620) Formalin-fixed and paraffin embedded: rat colitis tissue labeled with Anti-PDGFRA Pol...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-PDGFRA antibody (Platelet-Derived Growth Factor Receptor, alpha Polypeptide) (AA 1020-1070) (ABIN726620) Formalin-fixed and paraffin embedded: rat colitis tissue labeled with Anti-PDGFRA Pol...