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anti-Rat (Rattus) PDGFRA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PDGFRA Antibody (supplied by: Log in to see )

Antigen
Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies
  • AI115593
  • CD140a
  • Pdgfr-2
  • APDGFR
  • PDGFACE
  • CD140A
  • PDGFR-2
  • PDGFR2
  • RHEPDGFRA
  • PDGFR
  • PDGFR-A
  • platelet-derived growth factor receptor, alpha polypeptide
  • platelet derived growth factor receptor, alpha polypeptide
  • platelet-derived growth factor receptor alpha
  • PDGFRA
  • LOC100218386
  • Pdgfra
  • pdgfra
  • LOC100343006
Epitope
AA 1020-1070
51
25
19
18
18
18
17
16
15
15
15
15
14
12
11
11
9
7
6
5
5
5
5
4
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
451
213
143
4
3
3
3
3
2
1
1
1
1
1
1
Host
Rabbit
353
121
35
4
1
Clonality
Polyclonal
Conjugate
This PDGFRA antibody is un-conjugated
33
29
24
24
20
14
10
9
6
6
6
5
5
5
5
5
5
5
4
4
3
3
3
3
3
3
2
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
286
195
169
119
76
66
51
47
15
14
13
9
4
3
2
1
1
1
1
1
Options
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Catalog No. ABIN726620
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.081278 ABIN446762 ICC IF IHC (p) IHC WB Rabbit Log in to see Polyclonal 2
12.081278 ABIN784591 IHC (p) IP WB Rabbit IgG AA 1035-1053 Log in to see Polyclonal
12.081278 ABIN498160 IF IHC (p) WB Rabbit Log in to see Polyclonal
12.081278 ABIN710981 IF (p) IHC (p) WB Rabbit IgG pTyr762 Log in to see Polyclonal
1 ABIN372491 EIA IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN3043897 IHC (p) WB Rabbit IgG AA 968-1002, C-Term Log in to see Polyclonal
1 ABIN3044258 IHC (p) WB Rabbit IgG AA 1030-1043, C-Term Log in to see Polyclonal
1 ABIN3187792 ELISA IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN373777 IHC (p) Rabbit C-Term Log in to see Polyclonal
1 ABIN726629 IHC (p) WB HRP Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN726622 IHC (p) WB Biotin Rabbit IgG AA 1020-1070 Log in to see Polyclonal
1 ABIN710960 IHC (p) WB HRP Rabbit IgG pTyr988 Log in to see Polyclonal
1 ABIN710975 IHC (p) WB HRP Rabbit IgG pTyr579 Log in to see Polyclonal
1 ABIN744572 IHC (p) WB HRP Rabbit IgG pTyr857 Log in to see Polyclonal
1 ABIN744542 IHC (p) WB HRP Rabbit IgG pTyr1018 Log in to see Polyclonal
1 ABIN4344481 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN4344480 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN4344479 IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN710953 IHC (p) WB Biotin Rabbit IgG pTyr988 Log in to see Polyclonal
1 ABIN710968 IHC (p) WB Biotin Rabbit IgG pTyr579 Log in to see Polyclonal

Top referenced anti-PDGFRA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-PDGFRA Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 32 Antibodies 53 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 6 Antibodies 8 Antibodies
Immunofluorescence (IF) 16 Antibodies 16 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 67 Antibodies 67 Antibodies
Immunohistochemistry (IHC) 39 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 33 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 63 Antibodies
Flow Cytometry (FACS) 39 Antibodies
Functional Studies (Func) 1 Antibodies

General

Antigen Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies
Epitope AA 1020-1070
(51), (25), (19), (18), (18), (18), (17), (16), (15), (15), (15), (15), (14), (12), (11), (11), (9), (7), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(451), (213), (143), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(353), (121), (35), (4), (1)
Clonality
Polyclonal
Conjugate This PDGFRA antibody is un-conjugated
(33), (29), (24), (24), (20), (14), (10), (9), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(286), (195), (169), (119), (76), (66), (51), (47), (15), (14), (13), (9), (4), (3), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-PDGFRA Antibody

Target Details PDGFRA Application Details Handling References for anti-PDGFRA Antibody (ABIN726620) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human PDGF-R-A
Isotype IgG

Target Details PDGFRA

Product Details anti-PDGFRA Antibody Application Details Handling References for anti-PDGFRA Antibody (ABIN726620) Images back to top
Antigen
Alternative Name PDGFRA (PDGFRA Antibody Abstract)
Background

Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. Plays a role in cell migration and chemotaxis in wound healing. Plays a role in platelet activation, secretion of agonists from platelet granules, and in thrombin-induced platelet aggregation. Binding of its cognate ligands - homodimeric PDGFA, homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFC -leads to the activation of several signaling cascades, the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PIK3R1, PLCG1, and PTPN11. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, mobilization of cytosolic Ca(2+) and the activation of protein kinase C. Phosphorylates PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and thereby mediates activation of the AKT1 signaling pathway. Mediates activation of HRAS and of the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3 and STAT5A and/or STAT5B. Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalization of the activated receptor.

Subcellular location: Cytoplasm


Synonyms: CD140A, PDGFR2, PDGFR-2, RHEPDGFRA, Platelet-derived growth factor receptor alpha, PDGF-R-alpha, PDGFR-alpha, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a antigen, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, PDGFRA
Gene ID 5156
UniProt P16234
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-PDGFRA Antibody Target Details PDGFRA Handling References for anti-PDGFRA Antibody (ABIN726620) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details References for anti-PDGFRA Antibody (ABIN726620) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-PDGFRA Antibody (ABIN726620)

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details Handling Images back to top
Product cited in:

Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: "The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious." in: International journal of clinical and experimental pathology, Vol. 8, Issue 2, pp. 1525-34, 2015

Images

Product Details anti-PDGFRA Antibody Target Details PDGFRA Application Details Handling References for anti-PDGFRA Antibody (ABIN726620) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-PDGFRA antibody (Platelet-Derived Growth Factor Receptor, alpha Polypeptide) (AA 1020-1070) (ABIN726620) Formalin-fixed and paraffin embedded: rat colitis tissue labeled with Anti-PDGFRA Pol...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-PDGFRA antibody (Platelet-Derived Growth Factor Receptor, alpha Polypeptide) (AA 1020-1070) (ABIN726620) Formalin-fixed and paraffin embedded: rat colitis tissue labeled with Anti-PDGFRA Pol...