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anti-Human Phospholipase C gamma 1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Phospholipase C gamma 1 Antibody (supplied by: Log in to see )

Antigen
phospholipase C, gamma 1 (PLCG1) Antibodies
  • AI894140
  • Cded
  • nckap3
  • NCKAP3
  • Phosphb
  • PLC'1
  • Plc-1
  • Plc-gamma1
  • PLC-II
  • plc-ii
  • plc1
  • PLC1
  • plc148
  • PLC148
  • PLCbeta1
  • Plcg-1
  • plcgamma1
  • PLCgamma1
  • PPLCA
  • RATPHOSPHB
Reactivity
Human, Mouse (Murine), Rat (Rattus)
216
131
124
11
8
5
4
1
Host
Rabbit
191
29
Clonality
Polyclonal
Conjugate
This Phospholipase C gamma 1 antibody is un-conjugated
5
5
4
4
3
3
3
3
3
3
3
3
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
157
57
49
34
31
26
26
6
4
4
2
1
1
1
1
Supplier
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Catalog No. ABIN498180
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.30887908 ABIN337039 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
0.00090039347 ABIN319399 IHC (p) WB Rabbit Tyr771 Log in to see Polyclonal 5
0.00090039347 ABIN271786 IHC (p) WB Rabbit Log in to see Polyclonal
0.00090039347 ABIN372557 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
0.00090039347 ABIN744908 IF (p) IHC (p) WB Rabbit IgG AA 760-810, pTyr783 Log in to see Polyclonal 1
0.00090039347 ABIN2878866 IHC (p) ELISA WB Rabbit IgG AA 751-800 Log in to see Polyclonal
0.00090039347 ABIN1103661 IHC (p) IP WB Mouse IgG2a, kappa Log in to see 2B1
0.00090039347 ABIN2888604 IHC (p) ELISA WB Rabbit IgG AA 736-785 Log in to see Polyclonal
0.00090039347 ABIN744910 IHC (p) WB Biotin Rabbit IgG AA 760-810, pTyr783 Log in to see Polyclonal
0.00090039347 ABIN744917 IHC (p) WB HRP Rabbit IgG AA 760-810, pTyr783 Log in to see Polyclonal
0.00090039347 ABIN1860257 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 1091-1290 Log in to see Polyclonal
0.00090039347 ABIN1724472 IHC (p) IP WB Mouse IgG2a kappa Log in to see
0.00090039347 ABIN1738144 IHC (p) ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
0.00090039347 ABIN1924494 IHC (p) WB Rabbit AA 769-773 Log in to see Polyclonal
0.00090039347 ABIN744893 IF (p) IHC (p) WB Rabbit IgG pSer1248 Log in to see Polyclonal
0.00090039347 ABIN746665 IHC (p) WB Biotin Rabbit IgG pTyr771 Log in to see Polyclonal
0.00090039347 ABIN746672 IHC (p) WB HRP Rabbit IgG pTyr771 Log in to see Polyclonal
0.00090039347 ABIN711170 IHC (p) WB HRP Rabbit IgG pTyr775 Log in to see Polyclonal
0.00090039347 ABIN711163 IHC (p) WB Biotin Rabbit IgG pTyr775 Log in to see Polyclonal
0.00090039347 ABIN746663 IF (p) IHC (p) WB Rabbit IgG pTyr771 Log in to see Polyclonal

Top referenced anti-Phospholipase C gamma 1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-Phospholipase C gamma 1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 155 Antibodies 82 Antibodies 76 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Intracellular Staining (ICS) 4 Antibodies 2 Antibodies 2 Antibodies
Immunoprecipitation (IP) 22 Antibodies 4 Antibodies 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 27 Antibodies 16 Antibodies 16 Antibodies
Immunohistochemistry (IHC) 57 Antibodies 38 Antibodies 37 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 34 Antibodies 34 Antibodies 34 Antibodies

General

Antigen phospholipase C, gamma 1 (PLCG1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(216), (131), (124), (11), (8), (5), (4), (1)
Host Rabbit
(191), (29)
Clonality
Polyclonal
Conjugate This Phospholipase C gamma 1 antibody is un-conjugated
(5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(157), (57), (49), (34), (31), (26), (26), (6), (4), (4), (2), (1), (1), (1), (1)
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Product Details anti-Phospholipase C gamma 1 Antibody

Target Details Phospholipase C gamma 1 Application Details Handling Images
Specificity This antibody detects endogenous levels of PLC γ1 protein.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography using epitope-specific immunogen
Purity > 95 % (by SDS-PAGE)

Target Details Phospholipase C gamma 1

Product Details anti-Phospholipase C gamma 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PLCG1 (PLCG1 Antibody Abstract)
Background Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. There are many mammalian PLC isozymes, including PLC β1, PLC β2, PLC β3, PLC β4, PLC γ1, PLC γ2, PLC δ1, PLC δ2 and PLC ε. PLC γ1 is widely distributed in bronchiolar epithelium, type I and II pneumocytes and fibroblasts of the interstitial tissue. Actinregulatory protein Villin is tyrosine phosphorylated and associates with PLC γ1 in the brush border of intestinal epithelial cells. Villin regulates PLC γ1 activity by modifying its own ability to bind phosphatidylinositol 4,5-biphosphate. PLC γ1 binds α1β1 Integrin and modulates α1β1 Integrin-specific adhesion. PLC γ1 and Ca2+ play a direct role in VEGF-regulated endothelial growth, however this signaling pathway is not linked to FGF-mediated effects in primary endothelial cells.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-1, PLC gamma1 Phospholipase C-II, PLC-148, PLC-II, PLC-gamma-1, PLC1, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-gamma-1
Molecular Weight approx. 155 kDa
Gene ID 5335
NCBI Accession NP_877963
UniProt P19174
Pathways RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Phospholipase C gamma 1 Antibody Target Details Phospholipase C gamma 1 Handling Images back to top
Application Notes Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Phospholipase C gamma 1 Antibody Target Details Phospholipase C gamma 1 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-Phospholipase C gamma 1 Antibody Target Details Phospholipase C gamma 1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Phospholipase C gamma 1 antibody (phospholipase C, gamma 1) (ABIN498180) Immunohistochemistry analyzes of PLC γ1 antibody in paraffin-embedded human br...
Western Blotting (WB) image for anti-Phospholipase C gamma 1 antibody (phospholipase C, gamma 1) (ABIN498180) Western blot analysis of PLC γ1 antibody in extracts from COS7 cells.