anti-Mouse (Murine) Phospholipase C gamma 1 antibody for Intracellular Staining

Recommended Phospholipase C gamma 1 Antibody (supplied by: Log in to see )

Antigen
phospholipase C, gamma 1 (PLCG1) Antibodies
  • PLC'1
  • PLCbeta1
  • Phosphb
  • RATPHOSPHB
  • plc1
  • nckap3
  • plc-ii
  • plc148
  • plcgamma1
  • NCKAP3
  • PLC-II
  • PLC1
  • PLC148
  • PLCgamma1
  • AI894140
  • Cded
  • Plc-1
  • Plc-gamma1
  • Plcg-1
  • PPLCA
  • phospholipase C, beta 1 (phosphoinositide-specific)
  • phospholipase C, gamma 1
  • Plcb1
  • plcg1
  • PLCG1
  • Plcg1
  • LOC100349958
Epitope
N-Term
67
43
15
13
12
8
7
7
6
5
5
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
296
193
186
40
17
10
6
4
4
3
2
1
1
1
Host
Mouse
206
92
Clonality
Monoclonal
Conjugate
This Phospholipase C gamma 1 antibody is conjugated to Alexa Fluor 488
8
7
7
6
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
Application
Intracellular Staining (ICS)
231
94
90
43
43
38
38
27
18
4
4
3
2
2
1
1
1
Options
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Catalog No. ABIN1176865
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1176864 ICS Alexa Fluor 647 Mouse IgG1 N-Term Log in to see 10-PLCgamma

Similar anti-Phospholipase C gamma 1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Dog (Canine) Chicken
Immunofluorescence (fixed cells) (IF/ICC) 4 Antibodies 3 Antibodies 3 Antibodies
Cytometry by Time of Flight (CyTOF) 2 Antibodies 1 Antibodies 1 Antibodies
Western Blotting (WB) 229 Antibodies 137 Antibodies 131 Antibodies 8 Antibodies 2 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Intracellular Staining (ICS) 2 Antibodies 2 Antibodies 4 Antibodies 2 Antibodies 2 Antibodies
Immunoprecipitation (IP) 25 Antibodies 14 Antibodies 13 Antibodies

General

Antigen phospholipase C, gamma 1 (PLCG1) Antibodies
Epitope N-Term
(67), (43), (15), (13), (12), (8), (7), (7), (6), (5), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(296), (193), (186), (40), (17), (10), (6), (4), (4), (3), (2), (1), (1), (1)
Host Mouse
(206), (92)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Phospholipase C gamma 1 antibody is conjugated to Alexa Fluor 488
(8), (7), (7), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2)
Application Intracellular Staining (ICS)
(231), (94), (90), (43), (43), (38), (38), (27), (18), (4), (4), (3), (2), (2), (1), (1), (1)
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Product Details anti-Phospholipase C gamma 1 Antibody

Target Details Phospholipase C gamma 1 Application Details Handling Images
Brand BD Phosflow™
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Cow PLCgamma1 N-terminal region Peptide
Clone 10-PLCgamma
Isotype IgG1

Target Details Phospholipase C gamma 1

Product Details anti-Phospholipase C gamma 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PLC-gamma 1 (PLCG1 Antibody Abstract)
Background The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositol biphosphate to inositol triphosphate and diacylglycerol. The former causes release of calcium from the endoplasmic reticulum, while the latter is an activator of Protein Kinase C. Within the PLC family, PLCg is the only member that contains SH2 and SH3 domains. These domains enable it to interact with receptor tyrosine kinases and become enzymatically activated via phosphorylation. It exists as two isoforms: 1) PLCg1, which is ubiquitously expressed, and 2) PLCg2, found primarily in the lymphoid system. PLCg is essential for growth factor-induced cell motility and mitogenesis. PLCg1 null mice exhibit retarded embryonic growth and lethality in midgestation. Overexpression of PLCg is evident in several forms of cancer, and it has been identified as a key mediator of PDGF-dependent cellular transformation. Thus regulation of PLCg activity by growth factors is involved in cell growth and transformation. The 10/PLCgamma monoclonal antibody recognizes PLCg1, regardless of phosphorylation status. It does not cross-react with PLCg2.
Pathways RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals

Application Details

Product Details anti-Phospholipase C gamma 1 Antibody Target Details Phospholipase C gamma 1 Handling Images back to top
Sample Volume 20 μL
Restrictions For Research Use only

Handling

Product Details anti-Phospholipase C gamma 1 Antibody Target Details Phospholipase C gamma 1 Application Details Images back to top
Format Liquid
Buffer Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated to Alexa Fluor® 488 under optimum conditions, and unreacted Alexa Fluor® 488 was removed.