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anti-Human Phospholipase C gamma 2 antibody for Immunocytochemistry

Recommended Phospholipase C gamma 2 Antibody (supplied by: Log in to see )

Antigen
Phospholipase C gamma 2 (PLCG2) Antibodies
  • APLAID
  • FCAS3
  • Plcg-2
  • PLCgamma2
Epitope
Tyr1197
41
32
21
21
13
5
5
4
4
3
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
255
119
115
6
Host
Rabbit
190
65
Clonality
Monoclonal
Conjugate
This Phospholipase C gamma 2 antibody is un-conjugated
7
7
6
6
6
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
177
85
76
57
36
34
30
14
10
3
2
1
1
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Available images

Catalog No. ABIN256892
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010194078 ABIN957982 ICC WB Mouse IgG1 Log in to see 346404
0.0010194078 ABIN443064 ICC IF IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
0.0010194078 ABIN2884254 ICC IHC ELISA WB Rabbit IgG pTyr1217 Log in to see Polyclonal
0.0010194078 ABIN4346131 ICC IF WB Mouse IgG2 pTyr759 Log in to see MM0872-27K18
0.0010194078 ABIN442980 ICC IF IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
0.0010194078 ABIN1869846 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
0.0010194078 ABIN2987568 ICC IF WB Rabbit IgG pTyr753 Log in to see Polyclonal
0.0010194078 ABIN4238828 ELISA FACS ICC WB Mouse Log in to see 3A8B6
0.0010194078 ABIN4346134 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0010194078 ABIN4346135 ELISA FACS ICC IHC WB Mouse Log in to see 1E10C11
0.0010194078 ABIN4346136 ELISA FACS ICC IHC WB Mouse Log in to see 2D9E8
0.0010194078 ABIN2973656 ICC IF IP IHC WB Rabbit IgG Log in to see Polyclonal

Similar anti-Phospholipase C gamma 2 Antibodies

Application / Reactivity Human
ELISA 85 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunocytochemistry (ICC) 13 Antibodies
Immunofluorescence (IF) 39 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 34 Antibodies
Immunohistochemistry (IHC) 81 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 35 Antibodies
Immunoprecipitation (IP) 15 Antibodies
Intracellular Staining (ICS) 3 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Western Blotting (WB) 182 Antibodies

General

Antigen Phospholipase C gamma 2 (PLCG2) Antibodies
Epitope Tyr1197
(41), (32), (21), (21), (13), (5), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(255), (119), (115), (6)
Host Rabbit
(190), (65)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Phospholipase C gamma 2 antibody is un-conjugated
(7), (7), (6), (6), (6), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(177), (85), (76), (57), (36), (34), (30), (14), (10), (3), (2), (1), (1)
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Product Details anti-Phospholipase C gamma 2 Antibody

Target Details Phospholipase C gamma 2 Application Details Handling Images
Specificity This antibody detects PLCGammaII phosphorylated on tyrosine 1197.
No Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Tissue culture supernatant
Immunogen A phospho specific peptide corresponding to residues surrounding tyrosine 1197 of human PLCGammaII was used as an immunogen.
Clone EP1405Y
Isotype IgG

Target Details Phospholipase C gamma 2

Product Details anti-Phospholipase C gamma 2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PLCG2 (PLCG2 Antibody Abstract)
Background Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yielddiacylglycerols and water-soluble phosphorylated derivatives of the lipid head groups.The phospholipase C gamma-2 (PLC?II) is an enzyme that plays a crucial role inintracellular signal transduction pathways. This enzyme is important because of its rolein the generation of second messengers following the hydrolysis of phosphatidylinositol4,5-bisphosphate (1). PLC?II has been implicated in collagen-induced signaltransduction in platelets and antigen-dependent signaling in B-lymphocytes. It has beensuggested that tyrosine kinases activate PLC?II (2). Btk-deficient B cells exhibited amarked reduction in phosphorylation of the Src homology 2 (SH2)-SH3 linker regionsites, Tyr(753) and Tyr(759). Phosphorylation of both sites was restored by expressionof Tec, but not Syk, family kinases. In contrast, phosphorylation of the PLCgamma2carboxyl-terminal sites, Tyr(1197) and Tyr(1217), was unaffected by the absence offunctional Btk (3).
Gene Symbol: PLCG2
Gene ID 5336
Pathways RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Handling Images back to top
Application Notes This product is useful for: Western Blot, Immunocytochemistry, Immunoprecipitation. In Western blot this antibody detects a band at approximately 150kDa.
Recommended dilutions: Immunocytochemistry/Immunofluorescence 1:100-250, Immunoprecipitation 1:40, Western Blot 1:2000-20000
Restrictions For Research Use only

Handling

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details Images back to top
Format Liquid
Buffer PBS 49 % , Glycerol 50 % , BSA 0.05 % , Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment -20 °C.

Images

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Phospholipase C gamma 2 antibody (PLCG2) (Tyr1197) (ABIN256892) Western blot analysis on Raji cell lysates using anti-Phospho- PLCãII (pY1197) RabMA...
 image for anti-Phospholipase C gamma 2 antibody (PLCG2) (Tyr1197) (ABIN256892) anti-Phospholipase C gamma 2 (PLCG2) (Tyr1197) antibody (Image 2)