Browse our Phospholipase C gamma 2 (PLCG2) ELISA Kits

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Phospholipase C gamma 2 ELISA Kits (PLCG2)
On are 22 Phospholipase C gamma 2 (PLCG2) ELISA Kits from 10 different suppliers available. Additionally we are shipping Phospholipase C gamma 2 Antibodies (275) and Phospholipase C gamma 2 Proteins (4) and many more products for this protein. A total of 320 Phospholipase C gamma 2 products are currently listed.
APLAID, FCAS3, Plcg-2, PLCgamma2
list all ELISA KIts Gene Name GeneID UniProt
PLCG2 234779 Q8CIH5
PLCG2 29337 P24135
PLCG2 5336 P16885

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More ELISA Kits for Phospholipase C gamma 2 Interaction Partners

Mouse (Murine) Phospholipase C gamma 2 (PLCG2) interaction partners

  1. Results show that mice with the mutated Plcg2 gene were less prone to transformation into MALT lymphomas as a result of elevated Treg numbers, and decrease of pro-inflammatory cytokines.

  2. PLCgamma2 in clear cells plays an essential role in luminal expansion of the epididymis during the prepubertal period in mice

  3. platelet activation through GPVI (show GP6 ELISA Kits) and alphaIIbbeta3 utilizes PLCgamma2 because PLCgamma1 (show PLCG1 ELISA Kits) levels are insufficient to support responsiveness, but that PLCgamma1 (show PLCG1 ELISA Kits) can restore responsiveness if expressed at levels normally achieved by PLCgamma2.

  4. amarogentin prevents platelet activation through the inhibition of PLC (show HSPG2 ELISA Kits) gamma2-PKC (show PKC ELISA Kits) cascade and MAPK (show MAPK1 ELISA Kits) pathway

  5. PLCgamma2 and protein kinase C (show PKC ELISA Kits) are important upstream signals that regulate myelopoiesis through cytokines.

  6. inflammatory osteolysis can be abrogated by treatment with a molecule composed of the tandem SH2 domains of PLCgamma2.

  7. down-regulation of PLCgamma2-beta-catenin (show CTNNB1 ELISA Kits) pathway occurs in mice and humans and leads to myeloid-derived suppressor cells-mediated tumor expansion.

  8. a novel role of the PLCgamma2-IP(3)-Ca(2 (show CA2 ELISA Kits)+) cascade in the LPS (show TLR4 ELISA Kits)-induced innate immune response pathway where release of intracellular Ca(2 (show CA2 ELISA Kits)+) mediates TLR4 (show TLR4 ELISA Kits) trafficking and subsequent activation of IRF3 (show IRF3 ELISA Kits).

  9. VapB (show VAPB ELISA Kits) positively regulates RANKL (show TNFSF11 ELISA Kits)-mediated osteoclastogenesis via PLCgamma2-Ca(2 (show CA2 ELISA Kits)+)-NFAT (show NFATC1 ELISA Kits) signaling

  10. PLCgamma2 deficiency impairs Dectin-2 (show CLEC6A ELISA Kits)-induced NF-kappaB (show NFKB1 ELISA Kits) and MAPK (show MAPK1 ELISA Kits) activation in response to fungal infection

Human Phospholipase C gamma 2 (PLCG2) interaction partners

  1. R665W and L845F be referred to as allomorphic rather than hypermorphic mutations of PLCG2 Rerouting of the transmembrane signals emanating from BCR (show BCR ELISA Kits) and converging on PLCgamma2 through Rac (show AKT1 ELISA Kits) in ibrutinib-resistant CLL cells may provide novel drug treatment strategies to overcome ibrutinib resistance mediated by PLCG2 mutations or to prevent its development in ibrutinib-treated CLL patients.

  2. Data show that phospholipase Cgamma2 (PLCgamma2) is strongly expressed in B cell non-Hodgkin lymphoma and especially in a large subset of Diffuse large B-cell lymphoma (DLBCL).

  3. Characterization of the effect of missense point-mutation at R665W in PLCG2 on signaling mechanisms of ibrutinib resistance in chronic lymphocytic leukemia cells.

  4. amarogentin prevents platelet activation through the inhibition of PLC (show HSPG2 ELISA Kits) gamma2-PKC cascade and MAPK (show MAPK1 ELISA Kits) pathway

  5. PLCG2 missense mutation is a risk factor in the development of steroid sensitive nephrotic syndrome in childhood.

  6. The autoinhibitory C-terminal SH2 domain of phospholipase C (show PLC ELISA Kits)-gamma2 stabilizes B cell receptor signalosome assembly.

  7. The relationship between upstream tyrosine kinase (show TXK ELISA Kits) SYK (show SYK ELISA Kits) and its target, PLCgamma2, is maximally predictive and sufficient to distinguish chronic lymphocytic leukemia from healthy controls.

  8. Single-nucleotide polymorphisms in PLCG2 gene is associated with breast cancer risk after menopausal hormone replacement therapy.

  9. identified three distinct mutations in PLCgamma2 in two patients resistant to ibrutinib

  10. early Ca(2 (show CA2 ELISA Kits)+) fluxing provides feed-forward signal amplification by promoting anchoring of the PLCgamma2 C2 domain to phospho-SLP65 (show BLNK ELISA Kits).

Phospholipase C gamma 2 (PLCG2) Antigen Profile

Antigen Summary

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.

Alternative names and synonyms associated with Phospholipase C gamma 2 (PLCG2)

  • phospholipase C, gamma 2 (Plcg2) Elisa Kit
  • phospholipase C, gamma 2 (phosphatidylinositol-specific) (PLCG2) Elisa Kit
  • phospholipase C, gamma 2 (phosphatidylinositol-specific) (Plcg2) Elisa Kit
  • APLAID Elisa Kit
  • FCAS3 Elisa Kit
  • Plcg-2 Elisa Kit
  • PLCgamma2 Elisa Kit

Protein level used designations for PLCG2

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 , PLC-gamma-2 , phosphoinositide phospholipase C-gamma-2 , phospholipase C-gamma-2 , PLC-IV , phosphoinositide phospholipase C , phospholipase C-IV , phosphatidylinositol-specific phospholipase C

234779 Mus musculus
29337 Rattus norvegicus
5336 Homo sapiens
489692 Canis lupus familiaris
100518663 Sus scrofa
281988 Bos taurus
415805 Gallus gallus
100726796 Cavia porcellus
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