anti-Human Pleiotrophin antibody for Enzyme Immunoassay

Recommended Pleiotrophin Antibody (supplied by: Log in to see )

Antigen
Pleiotrophin (PTN) Antibodies
  • zHBNF
  • zgc:111787
  • harp
  • hbnf
  • X-PTF
  • hbgf8
  • negf1
  • ptn
  • PTN
  • HARP
  • HBGF8
  • HBNF
  • NEGF1
  • PTN-A
  • HB-GAM
  • HBBM
  • HBGF-8
  • OSF-1
  • HBBN
  • OSF
  • Osf-1
  • Osf1
  • Hbnf
  • pleiotrophin
  • Pleiotrophin
  • pleiotrophic factor beta
  • pleiotrophin-like
  • ptn
  • PTF-BETA
  • PTN
  • Ptn
  • LOC100351242
Epitope
AA 125-154, C-Term
27
21
11
9
8
8
6
4
4
3
2
2
1
1
1
Reactivity
Human
116
41
35
9
4
4
4
4
3
2
1
Host
Rabbit
100
16
11
4
Clonality
Polyclonal
Conjugate
This Pleiotrophin antibody is un-conjugated
13
8
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
110
65
46
30
16
13
6
4
4
2
1
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Catalog No. ABIN954196
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN115512 EIA IHC (p) WB Rabbit Log in to see Polyclonal 5

General

Antigen Pleiotrophin (PTN) Antibodies
Epitope AA 125-154, C-Term
(27), (21), (11), (9), (8), (8), (6), (4), (4), (3), (2), (2), (1), (1), (1)
Reactivity Human
(116), (41), (35), (9), (4), (4), (4), (4), (3), (2), (1)
Host Rabbit
(100), (16), (11), (4)
Clonality
Polyclonal
Conjugate This Pleiotrophin antibody is un-conjugated
(13), (8), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(110), (65), (46), (30), (16), (13), (6), (4), (4), (2), (1)
Pubmed 5 references available
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Product Details anti-Pleiotrophin Antibody

Target Details Pleiotrophin Application Details Handling References for anti-Pleiotrophin antibody (ABIN954196) Images
Specificity This antibody recognizes Pleiotrophin / PTN at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Purified through a Protein A column followed by peptide affinity purification
Immunogen Synthetic peptide - KLH conjugated - corresponding to the C-terminal region ( between 125-154aa) of human Pleiotrophin / PTN
Isotype Ig

Target Details Pleiotrophin

Product Details anti-Pleiotrophin Antibody Application Details Handling References for anti-Pleiotrophin antibody (ABIN954196) Images back to top
Antigen
Alternative Name Pleiotrophin / PTN (PTN Antibody Abstract)
Background Pleiotrophin is a heparin binding mitogenic protein. It has neurite extension activity.Synonyms: HB-GAM, HBBM, HBGF-8, HBNF-1, HBNF1, Heparin-binding brain mitogen, Heparin-binding growth factor 8, Heparin-binding growth-associated molecule, Heparin-binding neurite outgrowth-promoting factor 1, NEGF1, OSF-1, OSF1, Osteoblast-specific factor 1
Gene ID 5764
NCBI Accession NP_002816
Pathways RTK Signaling

Application Details

Product Details anti-Pleiotrophin Antibody Target Details Pleiotrophin Handling References for anti-Pleiotrophin antibody (ABIN954196) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Pleiotrophin Antibody Target Details Pleiotrophin Application Details References for anti-Pleiotrophin antibody (ABIN954196) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Pleiotrophin antibody (ABIN954196)

Product Details anti-Pleiotrophin Antibody Target Details Pleiotrophin Application Details Handling Images back to top
Background publications

Li, Nandini, Hattori, Bao, Murayama, Nakamura, Fukushima, Sugahara: "Structure of pleiotrophin- and hepatocyte growth factor-binding sulfated hexasaccharide determined by biochemical and computational approaches." in: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 27673-85, 2010

Dos Santos, Karaky, Renoir, Hamma-Kourbali, Albanese, Gobbo, Griscelli, Opolon, Dalle, Perricaudet, Courty, Delbé: "Antitumorigenic effects of a mutant of the heparin affin regulatory peptide on the U87 MG glioblastoma cell line." in: International journal of cancer. Journal international du cancer, Vol. 127, Issue 5, pp. 1038-51, 2010

Svensson, Pasupuleti, Walse, Malmsten, Mörgelin, Sjögren, Olin, Collin, Schmidtchen, Palmer, Egesten: "Midkine and pleiotrophin have bactericidal properties: preserved antibacterial activity in a family of heparin-binding growth factors during evolution." in: The Journal of biological chemistry, Vol. 285, Issue 21, pp. 16105-15, 2010

MBika, Baudouin, Courty, Achour: "Host factor pleiotrophin induces human immunodeficiency virus type 1 replication associated with inflammatory cytokine expression." in: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1346-53, 2010

Rose, Behm, Drgon, Johnson, Uhl: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010

Images

Product Details anti-Pleiotrophin Antibody Target Details Pleiotrophin Application Details Handling References for anti-Pleiotrophin antibody (ABIN954196) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Pleiotrophin (PTN) (AA 125-154), (C-Term) antibody (ABIN954196) Immunohistochemistry analysis in human brain tissue (Formalin-fixed, Paraffin-embedde...
Western Blotting (WB) image for anti-Pleiotrophin (PTN) (AA 125-154), (C-Term) antibody (ABIN954196) Western blot analysis in U251, NCI-H460 cell line lysates (35ug/lane) using Pleiotrop...