Browse our PPP3CA Proteins (PPP3CA)

On www.antibodies-online.com are 11 Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) Proteins from 7 different suppliers available. Additionally we are shipping PPP3CA Antibodies (122) and PPP3CA Kits (25) and many more products for this protein. A total of 164 PPP3CA products are currently listed.
Synonyms:
2900074D19Rik, AI841391, AW413465, calcineurin, caln, calna, calna1, ccn1, CN, CnA, cna1, fj46e08, ppp2b, ppp3ca, si:dkeyp-79c2.2, wu:fj46e08
list all proteins Gene Name GeneID UniProt
PPP3CA 5530 Q08209
PPP3CA 19055 P63328
PPP3CA 24674 P63329

PPP3CA Proteins (PPP3CA) by Origin

More Proteins for PPP3CA Interaction Partners

Human Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) interaction partners

  1. Studies indicate the importance of the AKAP79 (show AKAP5 Proteins)/PP2B/protein kinase A complex's role in synaptic long-term depression in the CA1 (show CA1 Proteins) region of the hippocampus.

  2. Ca(2 (show CA2 Proteins)+)/calcineurin (CaN)/nuclear factor of activated T-cells (NFAT (show NFATC1 Proteins)) c4 axis is required for neuritin (show NRN1 Proteins)-induced Kv4.2 (show KCND2 Proteins) transcriptional expression and potentiation of IA densities in cerebellum granule neurons.

  3. CN-A and nephrin were (show CABIN1 Proteins) clearly reduced in the kidneys of a 10-year-old boy who had relapsing steroid-resistant nephrotic syndrome (show NPHS1 Proteins).

  4. that KIF1Bbeta affects mitochondrial dynamics through calcineurin-dependent dephosphorylation of Dynamin-related protein 1 (DRP1 (show DNM1L Proteins)), causing mitochondrial fission and apoptosis

  5. for Aspergillus fumigatus, activation of macrophage calcineurin-NFAT (show NFATC1 Proteins) occurs via a phagosomal TLR9 (show TLR9 Proteins)-dependent and Bruton's tyrosine kinase (show BTK Proteins)-dependent signalling pathway that is independent of MyD88 (show MYD88 Proteins)

  6. Data indicate that both nuclear factors of activated T cells (NFATs) motifs partially compete for binding but do not fully displace each other on the calcineurin (Cn) epitope.

  7. Lysosomal calcium signaling regulates autophagy through calcineurin and TFEB (show TFEB Proteins).

  8. Human herpesvirus 6B U54 binds the calcineurin (CaN) phosphatase enzyme, causing improper dephosphorylation and nuclear translocation of NFAT (show NFATC1 Proteins) (nuclear factor of activated T cells) proteins, resulting in suboptimal IL-2 (show IL2 Proteins) gene transcription.

  9. KSR2 deficiency affects stromal interaction molecule 1 (STIM1 (show STIM1 Proteins))/ORAI1 puncta formation, which is correlated with cytoskeleton disorganization.

  10. These findings therefore provide initial support for the novel mechanistic hypothesis that oxidation-induced global and/or local conformational changes within calcineurin

Mouse (Murine) Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) interaction partners

  1. the CaN-Nfat (show NFATC1 Proteins) pathway regulates development and function of IFN-gamma (show IFNG Proteins)-producing gammadelta T cells.

  2. the expression of the full-length 60-kDa calcineurin protein is down-regulated due to over-activated calpain that cleaves calcineurin to form a 45-kDa fragment.

  3. Ca(2 (show CA2 Proteins)+)/calcineurin (CaN)/nuclear factor of activated T-cells (NFAT (show NFATC1 Proteins)) c4 axis is required for neuritin (show NRN1 Proteins)-induced Kv4.2 (show KCND2 Proteins) transcriptional expression and potentiation of IA densities in cerebellum granule neurons.

  4. AKAP150-calcineurin signaling dyad is essential for the activation of the phosphatase and the subsequent down-regulation of Kv channel currents following myocardial infarction.

  5. Calcineurin inhibitor (show RCAN1 Proteins) tacrolimus ameliorated proteinuria in nephrotic model by inhibiting the redistribution of CN-A and nephrin (show NPHS1 Proteins) at the slit diaphragm.

  6. global deficiency of catalytic subunit Ppp3cb (show PPP3CB Proteins), and tissue-specific ablation of regulatory subunit Ppp3r1 (show PPP3R1 Proteins) from skeletal muscle, but not adipose tissue or liver, led to protection from high-fat-diet-induced obesity

  7. Overexpression of the phosphatase calcineurin A prevents the development of a capillary/myocyte mismatch despite progressive myocardial hypertrophy.

  8. Catalytic subunits of the phosphatase calcineurin interact with NF-kappaB (show NFKB1 Proteins)-inducing kinase (NIK (show MAP4K4 Proteins)) and attenuate NIK (show MAP4K4 Proteins)-dependent gene expression

  9. Data indicate that calcineurin (CnAalpha-/- or CnAbeta (show PPP3CB Proteins)-/-) is required for pathological but not compensatory renal hypertrophy.

  10. We also confirmed that overexpression of RCAN1-1L could inhibit the transcriptional activation of an NFAT-dependent promoter in response to PMA and ionomycin by inhibiting Calcineurin activity in HEK293T cells

Cow (Bovine) Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) interaction partners

  1. The calmodulin binding region from residues 389 to 420 was modeled based on the structure of two other proteins having calmodulin binding domains with the same 1-8-14 structural motif as calcineurin.

Pig (Porcine) Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) interaction partners

PPP3CA Protein Profile

Protein Summary

catalytic subunit of Calcineurin (CaN), ubiquitously expressed Ca2+/CaM-dependent protein phosphatase\; mediates activities of transcription factors and ion channels\; involved in regulation of T-cell activation

Alternative names and synonyms associated with PPP3CA

  • protein phosphatase 3, catalytic subunit, alpha isozyme (PPP3CA)
  • protein phosphatase 3, catalytic subunit, alpha isoform (Ppp3ca)
  • protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (PPP3CA)
  • protein phosphatase 3, catalytic subunit, alpha isozyme (Ppp3ca)
  • protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) (ppp3ca)
  • protein phosphatase 3, catalytic subunit, alpha isozyme (ppp3ca)
  • serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like (LOC100205420)
  • 2900074D19Rik protein
  • AI841391 protein
  • AW413465 protein
  • calcineurin protein
  • caln protein
  • calna protein
  • calna1 protein
  • ccn1 protein
  • CN protein
  • CnA protein
  • cna1 protein
  • fj46e08 protein
  • ppp2b protein
  • ppp3ca protein
  • si:dkeyp-79c2.2 protein
  • wu:fj46e08 protein

Protein level used designations for PPP3CA

CAM-PRP catalytic subunit , calcineurin A alpha , calmodulin-dependent calcineurin A subunit alpha isoform , protein phosphatase 2B, catalytic subunit, alpha isoform , protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform , serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform , PP2B alpha 1 , PP2BA alpha , protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) , protein phosphatase 3, catalytic subunit, alpha isoform , Calcineurin subunit A alpha , protein phosphatase-2Ba , calcineurin catalytic subunit delta isoform , calcineurin catalytic subunit , protein phosphatase 3, catalytic subunit, alpha isozyme , serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like

GENE ID SPECIES
5530 Homo sapiens
19055 Mus musculus
286852 Bos taurus
395113 Gallus gallus
24674 Rattus norvegicus
380507 Xenopus laevis
397241 Sus scrofa
403486 Canis lupus familiaris
447196 Xenopus laevis
461403 Pan troglodytes
709773 Macaca mulatta
794574 Danio rerio
100014900 Monodelphis domestica
100067434 Equus caballus
100083890 Ornithorhynchus anatinus
100144934 Xenopus (Silurana) tropicalis
100174530 Pongo abelii
100205420 Hydra magnipapillata
100386369 Callithrix jacchus
100547009 Meleagris gallopavo
100583664 Nomascus leucogenys
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