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Browse our PPP3CA Proteins (PPP3CA)

Full name:
Protein Phosphatase 3, Catalytic Subunit, alpha Isozyme Proteins (PPP3CA)
On www.antibodies-online.com are 12 Protein Phosphatase 3, Catalytic Subunit, alpha Isozyme (PPP3CA) Proteins from 9 different suppliers available. Additionally we are shipping PPP3CA Antibodies (112) and PPP3CA Kits (39) and many more products for this protein. A total of 169 PPP3CA products are currently listed.
Synonyms:
2900074D19Rik, AI841391, AW413465, calcineurin, CALN, CALNA, Calna1, CCN1, CN, CnA, CNA1, fj46e08, PPP2B, ppp3ca, si:dkeyp-79c2.2, wu:fj46e08
list all proteins Gene Name GeneID UniProt
PPP3CA 19055 P63328
PPP3CA 5530 Q08209
PPP3CA 24674 P63329

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PPP3CA Proteins (PPP3CA) by Origin

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Top referenced PPP3CA Proteins

  1. Human PPP3CA Protein expressed in Escherichia coli (E. coli) - ABIN667318 : Ostenfeld, Bramsen, Lamy, Villadsen, Fristrup, Sørensen, Ulhøi, Borre, Kjems, Dyrskjøt, Orntoft: miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors. in Oncogene 2010 (PubMed)
    Show all 2 references for ABIN667318

More Proteins for PPP3CA Interaction Partners

Mouse (Murine) Protein Phosphatase 3, Catalytic Subunit, alpha Isozyme (PPP3CA) interaction partners

  1. Calcineurin inhi (show NPHS1 Proteins)bitor tacrolimus ameliorated proteinuria in nephrotic model by inhibiting the redistribution of CN-A and nephrin at the slit diaphragm.

  2. global deficiency of catalytic subunit Ppp3cb (show PPP3CB Proteins), and tissue-specific ablation of regulatory subunit Ppp3r1 (show PPP3R1 Proteins) from skeletal muscle, but not adipose tissue or liver, led to protection from high-fat-diet-induced obesity

  3. Overexpression of the phosphatase calcineurin A prevents the development of a capillary/myocyte mismatch despite progressive myocardial hypertrophy.

  4. Catalytic subunits of the phosphatase calcineurin interact with NF-kappaB (show NFKB1 Proteins)-inducing kinase (NIK (show MAP4K4 Proteins)) and attenuate NIK (show MAP4K4 Proteins)-dependent gene expression

  5. Data indicate that calcineurin (CnAalpha-/- or CnAbeta (show PPP3CB Proteins)-/-) is required for pathological but not compensatory renal hypertrophy.

  6. We also confirmed that overexpression of RCAN1 (show RCAN1 Proteins)-1L could inhibit the transcriptional activation of an NFAT (show NFATC1 Proteins)-dependent promoter in response to PMA and ionomycin by inhibiting Calcineurin activity in HEK293T cells

  7. A calcineurin- and NFAT-dependent pathway is involved in alpha-synuclein-induced degeneration of midbrain dopaminergic neurons in a Parkinson's disease mouse model.

  8. Calcineurin and its regulator, RCAN1 (show RCAN1 Proteins), confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion.

  9. KSR2 deficiency affects stromal interaction molecule 1 (STIM1 (show STIM1 Proteins))/ORAI1 (show TMEM132A Proteins) puncta formation, which is correlated with cytoskeleton disorganization.

  10. Data indicate that reduction in connexin43 (Cx43) and sodium channel NaV1.5 expression coincided with overexpression of transgene calcineurin A (CnA) and hypertrophy development and preceded significant presence of fibrosis.

Human Protein Phosphatase 3, Catalytic Subunit, alpha Isozyme (PPP3CA) interaction partners

  1. CN-A and nephrin (show NPHS1 Proteins) were clearly reduced in the kidneys of a 10-year-old boy who had relapsing steroid-resistant nephrotic syndrome.

  2. that KIF1Bbeta affects mitochondrial dynamics through calcineurin-dependent dephosphorylation of Dynamin-related protein 1 (DRP1 (show DNM1L Proteins)), causing mitochondrial fission and apoptosis

  3. for Aspergillus fumigatus, activation of macrophage calcineurin-NFAT (show NFATC1 Proteins) occurs via a phagosomal TLR9 (show TLR9 Proteins)-dependent and Bruton's tyrosine kinase (show BTK Proteins)-dependent signalling pathway that is independent of MyD88 (show MYD88 Proteins)

  4. Data indicate that both nuclear factors of activated T cells (NFATs) motifs partially compete for binding but do not fully displace each other on the calcineurin (Cn) epitope.

  5. Lysosomal calcium signaling regulates autophagy through calcineurin and TFEB (show TFEB Proteins).

  6. Human herpesvirus 6B U54 binds the calcineurin (CaN) phosphatase enzyme, causing improper dephosphorylation and nuclear translocation of NFAT (show NFATC1 Proteins) (nuclear factor of activated T cells) proteins, resulting in suboptimal IL-2 (show IL2 Proteins) gene transcription.

  7. KSR2 deficiency affects stromal interaction molecule 1 (STIM1 (show STIM1 Proteins))/ORAI1 puncta formation, which is correlated with cytoskeleton disorganization.

  8. These findings therefore provide initial support for the novel mechanistic hypothesis that oxidation-induced global and/or local conformational changes within calcineurin

  9. PKCepsilon (show PRKCE Proteins) may negatively regulate adverse myocardial remodeling by cooperating with calcineurin to downregulate fibrosis and induce transcription of cardioprotective wound healing genes, including COX-2

  10. Mutations on the hydrophobic face of Calcineurin distal helix disrupt the structure gained upon CaM (show CALM1 Proteins) binding.

Pig (Porcine) Protein Phosphatase 3, Catalytic Subunit, alpha Isozyme (PPP3CA) interaction partners

Cow (Bovine) Protein Phosphatase 3, Catalytic Subunit, alpha Isozyme (PPP3CA) interaction partners

  1. The calmodulin (show KRIT1 Proteins) binding region from residues 389 to 420 was modeled based on the structure of two other proteins having calmodulin (show KRIT1 Proteins) binding domains with the same 1-8-14 structural motif as calcineurin.

PPP3CA Protein Profile

Protein Summary

catalytic subunit of Calcineurin (CaN), ubiquitously expressed Ca2+/CaM-dependent protein phosphatase\; mediates activities of transcription factors and ion channels\; involved in regulation of T-cell activation

Alternative names and synonyms associated with PPP3CA

  • protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) (ppp3ca)
  • protein phosphatase 3, catalytic subunit, alpha isozyme (PPP3CA)
  • protein phosphatase 3, catalytic subunit, alpha isozyme (ppp3ca)
  • serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like (LOC100205420)
  • protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (PPP3CA)
  • protein phosphatase 3, catalytic subunit, alpha isoform (Ppp3ca)
  • protein phosphatase 3, catalytic subunit, alpha isozyme (Ppp3ca)
  • 2900074D19Rik protein
  • AI841391 protein
  • AW413465 protein
  • calcineurin protein
  • CALN protein
  • CALNA protein
  • Calna1 protein
  • CCN1 protein
  • CN protein
  • CnA protein
  • CNA1 protein
  • fj46e08 protein
  • PPP2B protein
  • ppp3ca protein
  • si:dkeyp-79c2.2 protein
  • wu:fj46e08 protein

Protein level used designations for PPP3CA

protein phosphatase 3, catalytic subunit, alpha isoform , protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform , serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform , protein phosphatase 3, catalytic subunit, alpha isozyme , calcineurin A alpha , serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like , protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) , CAM-PRP catalytic subunit , PP2B alpha 1 , PP2BA alpha , calmodulin-dependent calcineurin A subunit alpha isoform , protein phosphatase 2B, catalytic subunit, alpha isoform , calcineurin catalytic subunit , calcineurin catalytic subunit delta isoform , Calcineurin subunit A alpha , protein phosphatase-2Ba

GENE ID SPECIES
380507 Xenopus laevis
461403 Pan troglodytes
709773 Macaca mulatta
100014900 Monodelphis domestica
100067434 Equus caballus
100083890 Ornithorhynchus anatinus
100144934 Xenopus (Silurana) tropicalis
100174530 Pongo abelii
100205420 Hydra magnipapillata
100386369 Callithrix jacchus
100547009 Meleagris gallopavo
100583664 Nomascus leucogenys
395113 Gallus gallus
19055 Mus musculus
447196 Xenopus laevis
5530 Homo sapiens
403486 Canis lupus familiaris
397241 Sus scrofa
286852 Bos taurus
24674 Rattus norvegicus
794574 Danio rerio
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