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anti-Human Ret Proto-Oncogene antibody for Enzyme Immunoassay

Recommended Ret Proto-Oncogene Antibody (supplied by: Log in to see )

Antigen
Ret Proto-Oncogene (RET) Antibodies
  • c-ret
  • c-Ret
  • CDHF12
  • CDHR16
  • cret
  • etID315074.13
  • HSCR1
  • MEN2A
  • MEN2B
  • MTC1
  • PTC
  • RET
  • ret-A
  • RET-ELE1
  • ret1
  • RET9
  • RET51
  • wu:fd13h01
  • X-ret
  • xret
Epitope
AA 21-51, N-Term
70
41
38
26
22
20
14
14
13
13
12
9
8
8
8
8
7
6
5
5
5
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
352
98
89
12
5
3
1
Host
Rabbit
234
117
5
1
1
1
Clonality
Polyclonal
Conjugate
This Ret Proto-Oncogene antibody is un-conjugated
16
14
14
11
11
8
7
7
6
6
5
5
5
5
5
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
245
141
87
59
55
46
23
11
5
4
3
3
1
1
Supplier
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Catalog No. ABIN359926
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008854274 ABIN359924 EIA IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal
0.0008854274 ABIN359927 EIA IHC (p) Rabbit Ig C-Term Log in to see Polyclonal
0.0008854274 ABIN359925 EIA WB Rabbit Ig C-Term Log in to see Polyclonal
0.0008854274 ABIN954514 EIA IHC (p) WB Mouse IgG1 AA 896-1063 Log in to see 8D10C9

Top referenced anti-Ret Proto-Oncogene antibody for Enzyme Immunoassay

Similar anti-Ret Proto-Oncogene Antibodies

Application / Reactivity Human
ELISA 137 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 47 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 10 Antibodies
Immunofluorescence (IF) 23 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 55 Antibodies
Immunohistochemistry (IHC) 87 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 60 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Proximity Ligation Assay (PLA) 3 Antibodies
Western Blotting (WB) 243 Antibodies

General

Antigen Ret Proto-Oncogene (RET) Antibodies
Epitope AA 21-51, N-Term
(70), (41), (38), (26), (22), (20), (14), (14), (13), (13), (12), (9), (8), (8), (8), (8), (7), (6), (5), (5), (5), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(352), (98), (89), (12), (5), (3), (1)
Host Rabbit
(234), (117), (5), (1), (1), (1)
Clonality
Polyclonal
Conjugate This Ret Proto-Oncogene antibody is un-conjugated
(16), (14), (14), (11), (11), (8), (7), (7), (6), (6), (5), (5), (5), (5), (5), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(245), (141), (87), (59), (55), (46), (23), (11), (5), (4), (3), (3), (1), (1)
Pubmed 4 references available
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Product Details anti-Ret Proto-Oncogene Antibody

Target Details Ret Proto-Oncogene Application Details Handling References for anti-Ret Proto-Oncogene Antibody (ABIN359926) Images
Specificity This antibody recognizes Human RET (N-term).
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen KLH conjugated synthetic peptide between 21~51 amino acids from the N-terminal region of Human RET
Isotype Ig

Target Details Ret Proto-Oncogene

Product Details anti-Ret Proto-Oncogene Antibody Application Details Handling References for anti-Ret Proto-Oncogene Antibody (ABIN359926) Images back to top
Antigen
Alternative Name RET (RET Antibody Abstract)
Background RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.Synonyms: C-ret, CDHF12, Cadherin family member 12, Proto-oncogene tyrosine-protein kinase receptor ret
Gene ID 5979, 9606
UniProt P07949
Research Area Signaling, Kinases/Phosphatases
Pathways RTK Signaling

Application Details

Product Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Handling References for anti-Ret Proto-Oncogene Antibody (ABIN359926) Images back to top
Application Notes ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Application Details References for anti-Ret Proto-Oncogene Antibody (ABIN359926) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-Ret Proto-Oncogene Antibody (ABIN359926)

Product Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Application Details Handling Images back to top
Background publications

Da Silva, Maciel, Da Silva, Toledo, De Carvalho, Cerutti: "A novel germ-line point mutation in RET exon 8 (Gly(533)Cys) in a large kindred with familial medullary thyroid carcinoma." in: The Journal of clinical endocrinology and metabolism, Vol. 88, Issue 11, pp. 5438-43, 2003

McWhinney, Boru, Binkley, Peczkowska, Januszewicz, Neumann, Eng: "Intronic single nucleotide polymorphisms in the RET protooncogene are associated with a subset of apparently sporadic pheochromocytoma and may modulate age of onset." in: The Journal of clinical endocrinology and metabolism, Vol. 88, Issue 10, pp. 4911-6, 2003

DAlessio, Califano, Incoronato, Santelli, Florio, Schettini, Carlomagno, Cerchia, de Franciscis: "The tyrosine phosphatase Shp-2 mediates intracellular signaling initiated by Ret mutants." in: Endocrinology, Vol. 144, Issue 10, pp. 4298-305, 2003

Soares, Trovisco, Rocha, Lima, Castro, Preto, Máximo, Botelho, Seruca, Sobrinho-Simões: "BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC." in: Oncogene, Vol. 22, Issue 29, pp. 4578-80, 2003

Images

Product Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Application Details Handling References for anti-Ret Proto-Oncogene Antibody (ABIN359926) back to top
Supplier Images
 image for anti-Ret Proto-Oncogene antibody (RET) (AA 21-51) (ABIN359926) anti-Ret Proto-Oncogene (RET) (AA 21-51), (N-Term) antibody
 image for anti-Ret Proto-Oncogene antibody (RET) (AA 21-51) (ABIN359926) anti-Ret Proto-Oncogene (RET) (AA 21-51), (N-Term) antibody (Image 2)