anti-Human Ret Proto-Oncogene antibody for Immunofluorescence

Recommended Ret Proto-Oncogene Antibody (supplied by: Log in to see )

Antigen
Ret Proto-Oncogene (RET) Antibodies
  • c-ret
  • cret
  • etID315074.13
  • ret1
  • wu:fd13h01
  • X-ret
  • ret-A
  • xret
  • RET
  • MTC1
  • CDHF12
  • CDHR16
  • HSCR1
  • MEN2A
  • MEN2B
  • PTC
  • RET-ELE1
  • RET51
  • RET9
  • c-Ret
  • ret proto-oncogene receptor tyrosine kinase
  • ret proto-oncogene
  • ret
  • RET
  • Ret
Reactivity
Human
383
117
107
9
3
2
2
2
2
1
1
1
1
1
1
1
Host
Mouse
245
136
5
2
1
1
Clonality
Monoclonal
Conjugate
This Ret Proto-Oncogene antibody is un-conjugated
17
15
15
12
11
9
8
8
7
7
7
5
5
5
5
5
5
3
3
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
270
143
92
82
65
50
26
8
6
5
4
3
3
2
1
1
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Catalog No. ABIN659065
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.176544 ABIN4350058 ICC IF IHC IHC (p) Rabbit IgG Log in to see Polyclonal 2
11.176544 ABIN2705182 IC IF IHC WB Rabbit C-Term, pTyr1062 Log in to see Polyclonal
11.176544 ABIN2705184 IC IF IHC WB Rabbit C-Term Log in to see Polyclonal
11.176544 ABIN2705183 IC IF IHC WB Rabbit C-Term Log in to see Polyclonal
11.176544 ABIN4350067 ICC IF IHC (p) WB Mouse IgM kappa Log in to see 188CT11-2-3
11.176544 ABIN3032459 IF IHC ELISA WB Mouse IgM, kappa Log in to see 188CT11-2-3
11.176544 ABIN1450227 IF ELISA WB Chicken IgY Log in to see Polyclonal
1 ABIN1450578 IF IHC ELISA WB Rabbit IgG C-Term Log in to see Polyclonal 2
1 ABIN3186734 ELISA IF IHC WB Rabbit IgG Thr77 Log in to see Polyclonal
1 ABIN3183018 ELISA IF IHC Rabbit IgG pTyr905 Log in to see Polyclonal
1 ABIN1450308 IF IHC ELISA Rabbit IgG pTyr905, C-Term Log in to see Polyclonal
1 ABIN2884297 ELISA IF IHC (p) WB Rabbit IgG AA 881-930 Log in to see Polyclonal
1 ABIN1500667 IF IHC (p) WB Mouse IgM, kappa Log in to see
1 ABIN2885522 ELISA IF IHC (p) Rabbit IgG pTyr905 Log in to see Polyclonal
1 ABIN2744030 ICC IF IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN2744031 ICC IF IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN2744032 ICC IF IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN2350339 IF IHC ELISA WB Mouse IgM kappa Log in to see 188CT11-2-3
1 ABIN4350057 ICC IF IHC IHC (p) Rabbit IgG Log in to see Polyclonal
1 ABIN4904992 IF IHC WB Mouse IgG Log in to see

General

Antigen Ret Proto-Oncogene (RET) Antibodies
Reactivity Human
(383), (117), (107), (9), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(245), (136), (5), (2), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Ret Proto-Oncogene antibody is un-conjugated
(17), (15), (15), (12), (11), (9), (8), (8), (7), (7), (7), (5), (5), (5), (5), (5), (5), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(270), (143), (92), (82), (65), (50), (26), (8), (6), (5), (4), (3), (3), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-Ret Proto-Oncogene Antibody

Target Details Ret Proto-Oncogene Application Details Handling ProductDetails: References for anti-Ret Proto-Oncogene antibody (ABIN659065) Images
Specificity This RET Monoclonal antibody was raised using purified His-tagged recombinant human RET.
Purification Ascites
Immunogen This RET Monoclonal antibody was raised using purified His-tagged recombinant human RET.
Clone 188CT11-2-3
Isotype IgM, kappa

Target Details Ret Proto-Oncogene

Product Details anti-Ret Proto-Oncogene Antibody Application Details Handling ProductDetails: References for anti-Ret Proto-Oncogene antibody (ABIN659065) Images back to top
Antigen
Alternative Name RET (RET Antibody Abstract)
Background This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.
Synonyms: Proto-oncogene tyrosine-protein kinase receptor Ret,RET,CDHF12
Pathways: Pathways in cancer, Endocytosis, Thyroid cancer
Molecular Weight 124319 Da
Gene ID 5979
UniProt P07949
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Cancer, Chromatin, Signaling, Neurology
Pathways RTK Signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation

Application Details

Product Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Handling ProductDetails: References for anti-Ret Proto-Oncogene antibody (ABIN659065) Images back to top
Application Notes WB = 1:500-16000, IHC (p) = 1:50-100, IF = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Application Details ProductDetails: References for anti-Ret Proto-Oncogene antibody (ABIN659065) Images back to top
Format Liquid
Buffer Crude ascites with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

ProductDetails: References for anti-Ret Proto-Oncogene antibody (ABIN659065)

Product Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Application Details Handling Images back to top
Background publications

Siqueira, Romitti, da Rocha, Ceolin, Meotti, Estivalet, Puñales, Maia: "The RET polymorphic allele S836S is associated with early metastatic disease in patients with hereditary or sporadic medullary thyroid carcinoma." in: Endocrine-related cancer, Vol. 17, Issue 4, pp. 953-63, 2010

Gockel, Schumacher, Gockel, Lang, Haaf, Nöthen: "Achalasia: will genetic studies provide insights?" in: Human genetics, Vol. 128, Issue 4, pp. 353-64, 2010

Kim, Jung, Lim, Sung, Whang, Jo, Lee, Shin, Kim, Ryu, Kim: "A study of RET proto-oncogene polymorphisms in association with lung cancer risk in the Korean population." in: Anticancer research, Vol. 30, Issue 9, pp. 3621-7, 2010

Images

Product Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Application Details Handling ProductDetails: References for anti-Ret Proto-Oncogene antibody (ABIN659065) back to top
Supplier Images
Western Blotting (WB) image for anti-Ret Proto-Oncogene (RET) antibody (ABIN659065) RET western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates th...
Immunohistochemistry (IHC) image for anti-Ret Proto-Oncogene (RET) antibody (ABIN659065) RET Monoclonal( Ascites) immunohistochemistry analysis in formalin fixed and paraffi...
Immunofluorescence (IF) image for anti-Ret Proto-Oncogene (RET) antibody (ABIN659065) Confocal immunofluorescent analysis of RET Antibody (Ascites) with MDA-MB231 cell fol...