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|Application / Reactivity||Human|
|ELISA (Capture)||1 Antibodies|
|Enzyme Immunoassay (EIA)||5 Antibodies|
|Flow Cytometry (FACS)||47 Antibodies|
|Immunochromatography (IC)||3 Antibodies|
|Immunocytochemistry (ICC)||10 Antibodies|
|Immunofluorescence (IF)||23 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||55 Antibodies|
|Immunohistochemistry (IHC)||87 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||60 Antibodies|
|Immunoprecipitation (IP)||4 Antibodies|
|Proximity Ligation Assay (PLA)||3 Antibodies|
|Western Blotting (WB)||243 Antibodies|
|Antigen||Ret Proto-Oncogene (RET) Antibodies|
|Conjugate||This Ret Proto-Oncogene antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|3 references available|
|Supplier||Log in to see|
Product Details anti-Ret Proto-Oncogene AntibodyTarget Details Ret Proto-Oncogene Application Details Handling References for anti-Ret Proto-Oncogene Antibody (ABIN115113) Images
Reacts to Ret Oncoprotein.
Cellular Localization: Cytoplasmic.
|Immunogen||BALB/C mice were injected with recombinant protein encoding the extreme C-terminal cytoplasmic region of the human ret oncoprotein.|
Target Details Ret Proto-OncogeneProduct Details anti-Ret Proto-Oncogene Antibody Application Details Handling References for anti-Ret Proto-Oncogene Antibody (ABIN115113) Images back to top
|Alternative Name||RET (RET Antibody Abstract)|
|Background||Ret proto-oncogene encodes a cell surface glycoprotein belonging to a member of the receptor tyrosine kinase family and is located on chromosome 10q11.2. Ret is observed in several regions of the central nervous system, in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia, in motor neurons in the spinal cord and hindbrain.Synonyms: C-ret, CDHF12, Cadherin family member 12, Proto-oncogene tyrosine-protein kinase receptor ret|
|Research Area||Signaling, Kinases/Phosphatases|
Application DetailsProduct Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Handling References for anti-Ret Proto-Oncogene Antibody (ABIN115113) Images back to top
Immunohistochemistry on paraffin embedded sections: diluted of 1: 10-1: 20 in an ABC method (90 minutes at room temperature), requires hightemperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Small intestine.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Application Details References for anti-Ret Proto-Oncogene Antibody (ABIN115113) Images back to top
|Buffer||Sodium azide as preservative|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-Ret Proto-Oncogene Antibody (ABIN115113)Product Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Application Details Handling Images back to top
Nosrat, Tomac, Hoffer, Olson: "Cellular and developmental patterns of expression of Ret and glial cell line-derived neurotrophic factor receptor alpha mRNAs." in: Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale, Vol. 115, Issue 3, pp. 410-22, 1997
Williams, Rooney, Carss, Cummins, Thomas, Williams: "Analysis of the RET proto-oncogene in sporadic parathyroid adenomas." in: The Journal of pathology, Vol. 180, Issue 2, pp. 138-41, 1997
Nakamura, Ishizaka, Nagao, Hara, Ishikawa: "Expression of the ret proto-oncogene product in human normal and neoplastic tissues of neural crest origin." in: The Journal of pathology, Vol. 172, Issue 3, pp. 255-60, 1994
ImagesProduct Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Application Details Handling References for anti-Ret Proto-Oncogene Antibody (ABIN115113) back to top