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anti-Mouse (Murine) Ret Proto-Oncogene antibody for Immunohistochemistry (Frozen Sections)

Recommended Ret Proto-Oncogene Antibody (supplied by: Log in to see )

Antigen
Ret Proto-Oncogene (RET) Antibodies
  • c-ret
  • c-Ret
  • CDHF12
  • CDHR16
  • cret
  • etID315074.13
  • HSCR1
  • MEN2A
  • MEN2B
  • MTC1
  • PTC
  • RET
  • ret-A
  • RET-ELE1
  • ret1
  • RET9
  • RET51
  • wu:fd13h01
  • X-ret
  • xret
Epitope
Extracellular Domain
70
42
38
26
22
20
14
14
13
12
9
8
8
8
8
8
6
6
5
5
5
4
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
325
98
88
12
5
3
1
Host
Goat
232
92
4
1
1
1
Clonality
Polyclonal
Conjugate
This Ret Proto-Oncogene antibody is un-conjugated
16
14
14
11
10
8
5
5
5
5
5
5
5
5
5
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
226
138
84
55
55
27
20
8
5
5
3
3
1
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Catalog No. ABIN289533
$ 1,011.26
Plus shipping costs $45.00

Similar anti-Ret Proto-Oncogene Antibodies

Application / Reactivity Mouse (Murine)
ELISA 21 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 44 Antibodies
Immunohistochemistry (IHC) 11 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies
Western Blotting (WB) 46 Antibodies

General

Antigen Ret Proto-Oncogene (RET) Antibodies
Epitope Extracellular Domain
(70), (42), (38), (26), (22), (20), (14), (14), (13), (12), (9), (8), (8), (8), (8), (8), (6), (6), (5), (5), (5), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(325), (98), (88), (12), (5), (3), (1)
Host Goat
(232), (92), (4), (1), (1), (1)
Clonality
Polyclonal
Conjugate This Ret Proto-Oncogene antibody is un-conjugated
(16), (14), (14), (11), (10), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(226), (138), (84), (55), (55), (27), (20), (8), (5), (5), (3), (3), (1)
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Product Details anti-Ret Proto-Oncogene Antibody

Target Details Ret Proto-Oncogene Application Details Handling Images
Purification Purified
Immunogen Ret antibody was raised in goat using NSO derived murine ret extracellular domain as the immunogen.

Target Details Ret Proto-Oncogene

Product Details anti-Ret Proto-Oncogene Antibody Application Details Handling Images back to top
Antigen
Alternative Name Ret (RET Antibody Abstract)
Background The Ret proto-oncogene (c-Ret) is a receptor tyrosine kinase that functions as a multicompetent receptor complex in conjunction with other membrane-bound ligand-binding GDNF family receptors. Ligands that bind the Ret receptor include the glial cell line-derived neurotropic factor (GDNF) and its congeners neurturin, persephin and artemin. Alterations in the corresponding Ret gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma and a congenital developmental disorder known as Hirschsprung’s disease. The Tyr905 residue located in the Ret kinase domain plays a crucial role in Ret catalytic and biological activity. Substitution of Phe for Tyr905 dramatically inhibits Ret autophosphorylation activity.
Research Area Cancer, Tyrosine Kinases, Signaling, Kinases/Phosphatases
Pathways RTK Signaling

Application Details

Product Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Handling Images back to top
Application Notes ELISA: 0.5-1 μg/mL, IHC-F: 5 μg/mL, IHC-P: 10-15 μg/mL, WB: 0.1-0.2 μg/mL
Optimal conditions should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Ret Proto-Oncogene Antibody Target Details Ret Proto-Oncogene Application Details Images back to top
Format Lyophilized
Reconstitution Reconstitute with 1 mL of PBS.
Buffer Lyophilized from PBS, pH 7.2 containing 5 % trehalose.
Handling Advice Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
Storage -80 °C
Storage Comment Aliquot and store at -70 °C or lower.