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anti-Human RHEB antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended RHEB Antibody (supplied by: Log in to see )

Antigen
Ras Homolog Enriched in Brain (RHEB) Antibodies
  • im:7161941
  • RHEB
  • rheb2
  • RHEB2
  • zgc:153231
Epitope
AA 111-142, C-Term
13
9
8
8
8
7
6
3
2
1
1
1
1
1
Reactivity
Human
90
53
52
1
1
1
1
Host
Rabbit
83
7
Clonality
Polyclonal
Conjugate
This RHEB antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
68
30
25
14
11
5
4
2
1
Supplier
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Catalog No. ABIN954537
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34458184 ABIN500597 EIA IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 4
0.34458184 ABIN214467 IHC (p) WB Rabbit Log in to see Polyclonal
0.00089488085 ABIN655712 IHC (p) WB Rabbit Ig AA 104-134, C-Term Log in to see Polyclonal
0.00089488085 ABIN303237 IHC (p) WB Rabbit Middle Region Log in to see Polyclonal
0.00089488085 ABIN704771 IF (p) IHC (p) Rabbit IgG AA 100-140 Log in to see Polyclonal
0.00089488085 ABIN605028 FACS IHC (p) WB Rabbit IgG Asn50 Log in to see Polyclonal
0.00089488085 ABIN1738859 IF IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.00089488085 ABIN704773 IHC (p) Biotin Rabbit IgG AA 100-140 Log in to see Polyclonal
0.00089488085 ABIN704780 IHC (p) HRP Rabbit IgG AA 100-140 Log in to see Polyclonal
0.00089488085 ABIN2627632 IHC (p) Rabbit IgG AA 107-156 Log in to see Polyclonal
0.00089488085 ABIN1810284 IHC (p) WB Rabbit AA 111-142 Log in to see Polyclonal
0.00089488085 ABIN2744044 IHC (p) ELISA WB Mouse IgG1, kappa Log in to see 2C11
0.00089488085 ABIN2964045 IHC (p) ELISA WB Mouse IgG1 kappa Log in to see 2C11
0.00089488085 ABIN2766782 IHC (p) WB Rabbit Log in to see Polyclonal

Top referenced anti-RHEB antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-RHEB Antibodies

Application / Reactivity Human
ELISA 30 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunofluorescence (IF) 4 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 25 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 15 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 70 Antibodies

General

Antigen Ras Homolog Enriched in Brain (RHEB) Antibodies
Epitope AA 111-142, C-Term
(13), (9), (8), (8), (8), (7), (6), (3), (2), (1), (1), (1), (1), (1)
Reactivity Human
(90), (53), (52), (1), (1), (1), (1)
Host Rabbit
(83), (7)
Clonality
Polyclonal
Conjugate This RHEB antibody is un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(68), (30), (25), (14), (11), (5), (4), (2), (1)
Pubmed 3 references available
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Product Details anti-RHEB Antibody

Target Details RHEB Application Details Handling References for anti-RHEB Antibody (ABIN954537) Images
Specificity This antibody recognizes Human
Purification Affinity Chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 111-142 amino acids from the C-terminal region of Human RHEB. Genename: RHEB
Isotype Ig

Target Details RHEB

Product Details anti-RHEB Antibody Application Details Handling References for anti-RHEB Antibody (ABIN954537) Images back to top
Antigen
Alternative Name RHEB (RHEB Antibody Abstract)
Background This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22Synonyms: GTP-binding protein Rheb, RHEB2, Ras homolog enriched in brain
Molecular Weight 20497 Da
Gene ID 6009
NCBI Accession NP_005605
Research Area Cancer, Transcription Factors
Pathways RTK Signaling

Application Details

Product Details anti-RHEB Antibody Target Details RHEB Handling References for anti-RHEB Antibody (ABIN954537) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-RHEB Antibody Target Details RHEB Application Details References for anti-RHEB Antibody (ABIN954537) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-RHEB Antibody (ABIN954537)

Product Details anti-RHEB Antibody Target Details RHEB Application Details Handling Images back to top
Background publications

Zheng, Liu, Liu, Li, Yu, Luo: "Ras homologue enriched in brain is a critical target of farnesyltransferase inhibitors in non-small cell lung cancer cells." in: Cancer letters, Vol. 297, Issue 1, pp. 117-25, 2010

Kim, Ha, Lee, Huston, Kim, Jang, Suh, Houslay, Ryu: "Cyclic AMP controls mTOR through regulation of the dynamic interaction between Rheb and phosphodiesterase 4D." in: Molecular and cellular biology, Vol. 30, Issue 22, pp. 5406-20, 2010

Karassek, Berghaus, Schwarten, Goemans, Ohse, Kock, Jockers, Neumann, Gottfried, Herrmann, Heumann, Stoll: "Ras homolog enriched in brain (Rheb) enhances apoptotic signaling." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 33979-91, 2010

Images

Product Details anti-RHEB Antibody Target Details RHEB Application Details Handling References for anti-RHEB Antibody (ABIN954537) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-RHEB antibody (Ras Homolog Enriched in Brain) (AA 111-142) (ABIN954537) Formalin fixed, paraffin embedded human skeletal muscle stained with RHEB Antibody (C...
Western Blotting (WB) image for anti-RHEB antibody (Ras Homolog Enriched in Brain) (AA 111-142) (ABIN954537) Western blot analysis of RHEB Antibody (C-term) in MDA-MB231 cell line lysates (35ug/...