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anti-Mouse (Murine) RYK antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended RYK Antibody (supplied by: Log in to see )

Antigen
RYK Receptor-Like Tyrosine Kinase (RYK) Antibodies
  • AW536699
  • D3S3195
  • d3s3195
  • ERK-3
  • JTK5
  • jtk5
  • JTK5A
  • jtk5a
  • MGC114645
  • RYK
  • ryk1
  • RYK1
  • Vik
  • wu:fb37b12
  • wu:fi05b06
  • zgc:158381
Epitope
AA 150-200
19
17
15
14
14
11
7
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
92
19
8
1
1
1
Host
Rabbit
65
23
10
3
Clonality
Polyclonal
Conjugate
This RYK antibody is un-conjugated
9
9
8
8
8
8
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
90
68
30
5
2
2
1
1
1
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Catalog No. ABIN359937
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089488085 ABIN392050 IHC (p) WB Rabbit Ig AA 160-190 Log in to see Polyclonal 2

Top referenced anti-RYK antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-RYK Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 2 Antibodies 8 Antibodies 62 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 1 Antibodies 3 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 2 Antibodies
Immunofluorescence (IF) 1 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 2 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 2 Antibodies 2 Antibodies
Western Blotting (WB) 7 Antibodies 15 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunochromatography (IC) 1 Antibodies

General

Antigen RYK Receptor-Like Tyrosine Kinase (RYK) Antibodies
Epitope AA 150-200
(19), (17), (15), (14), (14), (11), (7), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(92), (19), (8), (1), (1), (1)
Host Rabbit
(65), (23), (10), (3)
Clonality
Polyclonal
Conjugate This RYK antibody is un-conjugated
(9), (9), (8), (8), (8), (8)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(90), (68), (30), (5), (2), (2), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-RYK Antibody

Target Details RYK Application Details Handling References for anti-RYK Antibody (ABIN359937) Images
Specificity This antibody reacts to RYK.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected within aa 150~200 of human RYK.
Isotype Ig

Target Details RYK

Product Details anti-RYK Antibody Application Details Handling References for anti-RYK Antibody (ABIN359937) Images back to top
Antigen
Alternative Name Tyrosine-Protein Kinase RYK (RYK Antibody Abstract)
Background RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.Synonyms: JTK5A
Gene ID 6259, 9606
UniProt P34925
Research Area Kinases/Phosphatases
Pathways RTK Signaling, WNT Signaling

Application Details

Product Details anti-RYK Antibody Target Details RYK Handling References for anti-RYK Antibody (ABIN359937) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-RYK Antibody Target Details RYK Application Details References for anti-RYK Antibody (ABIN359937) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-RYK Antibody (ABIN359937)

Product Details anti-RYK Antibody Target Details RYK Application Details Handling Images back to top
Background publications

Trivier, Ganesan: "RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 23037-43, 2002

Katso, Russell, Ganesan: "Functional analysis of H-Ryk, an atypical member of the receptor tyrosine kinase family." in: Molecular and cellular biology, Vol. 19, Issue 9, pp. 6427-40, 1999

Wang, Katso, Butler, Hanby, Poulsom, Jones, Sheer, Ganesan: "H-RYK, an unusual receptor kinase: isolation and analysis of expression in ovarian cancer." in: Molecular medicine (Cambridge, Mass.), Vol. 2, Issue 2, pp. 189-203, 1996

Tamagnone, Partanen, Armstrong, Lasota, Ohgami, Tazunoki, LaForgia, Huebner, Alitalo: "The human ryk cDNA sequence predicts a protein containing two putative transmembrane segments and a tyrosine kinase catalytic domain." in: Oncogene, Vol. 8, Issue 7, pp. 2009-14, 1993

Stacker, Hovens, Vitali, Pritchard, Baker, Sutherland, Wilks: "Molecular cloning and chromosomal localisation of the human homologue of a receptor related to tyrosine kinases (RYK)." in: Oncogene, Vol. 8, Issue 5, pp. 1347-56, 1993

Images

Product Details anti-RYK Antibody Target Details RYK Application Details Handling References for anti-RYK Antibody (ABIN359937) back to top
Supplier Images
 image for anti-RYK antibody (RYK Receptor-Like Tyrosine Kinase) (AA 150-200) (ABIN359937) anti-RYK Receptor-Like Tyrosine Kinase (RYK) (AA 150-200) antibody
 image for anti-RYK antibody (RYK Receptor-Like Tyrosine Kinase) (AA 150-200) (ABIN359937) anti-RYK Receptor-Like Tyrosine Kinase (RYK) (AA 150-200) antibody (Image 2)