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|Antigen||RYK Receptor-Like Tyrosine Kinase (RYK) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This RYK antibody is un-conjugated Alternatives|
Western Blotting (WB)
|1 reference available|
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Product Details anti-RYK AntibodyTarget Details RYK Application Details Handling References for anti-RYK antibody (ABIN264516) Images
|Specificity||This antibody reacts to Receptor-Like Tyrosine Kinase.|
|Immunogen||Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the human RYK protein and mouse myeloma Ag8563 cells. Sequence common in human, mouse and rat.|
|Clone||F35 P7 D7 F5|
Target Details RYKProduct Details anti-RYK Antibody Application Details Handling References for anti-RYK antibody (ABIN264516) Images back to top
|Alternative Name||Tyrosine-Protein Kinase RYK (RYK Antibody Abstract)|
|Background||RYK (Receptor like Tyrosine kinase 1) is in the Tyrosine family of receptor kinases. It is found in the plasma membrane of heart, prostate and kidney cells. RYK contains 604 amino acids and it contains one WIF domain. It functions as a potential growth factor receptor protein tyrosine kinase. RYK are divergent from those of other classic receptor tyrosine kinases. It is an orphan receptor that contains a catalytically inactive tyrosine kinase related domain. RYK is expressed in nestin positive progenitor cells and neurons, and in a certain population of oligodendrocytes, O2A progenitor cells, and type 2 astrocytes in developing CNS.Synonyms: JTK5A|
|Pathways||RTK Signaling, WNT Signaling, Regulation of Cell Size|
Application DetailsProduct Details anti-RYK Antibody Target Details RYK Handling References for anti-RYK antibody (ABIN264516) Images back to top
Western Blot: 1-5 μg/mL. Positive Control: HCT116 cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-RYK Antibody Target Details RYK Application Details References for anti-RYK antibody (ABIN264516) Images back to top
|Buffer||Phosphate buffered saline with 0.08 % sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
References for anti-RYK antibody (ABIN264516)Product Details anti-RYK Antibody Target Details RYK Application Details Handling Images back to top
Graham, Dawson, Mullaney, Snodgrass, Earp: "Cloning and mRNA expression analysis of a novel human protooncogene, c-mer." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 5, Issue 6, pp. 647-57, 1994
ImagesProduct Details anti-RYK Antibody Target Details RYK Application Details Handling References for anti-RYK antibody (ABIN264516) back to top