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Browse our RYK Proteins (RYK)

Full name:
RYK Receptor-Like Tyrosine Kinase Proteins (RYK)
On www.antibodies-online.com are 10 RYK Receptor-Like Tyrosine Kinase (RYK) Proteins from 4 different suppliers available. Additionally we are shipping RYK Antibodies (102) and RYK Kits (2) and many more products for this protein. A total of 120 RYK products are currently listed.
Synonyms:
AW536699, D3S3195, ERK-3, JTK5, JTK5A, MGC114645, RYK, RYK1, Vik, wu:fb37b12, wu:fi05b06, zgc:158381
list all proteins Gene Name GeneID UniProt
RYK 6259 P34925
RYK 20187 Q01887
Rat RYK RYK 140585  

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RYK Proteins (RYK) by Origin

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More Proteins for RYK Interaction Partners

Zebrafish RYK Receptor-Like Tyrosine Kinase (RYK) interaction partners

  1. RYK and VANGL2 (show VANGL2 Proteins) proteins form a complex, whereas RYK also activated RhoA (show RHOA Proteins), a downstream effector of PCP (show PRCP Proteins) signaling.

  2. Data suggest that full-length Ryk conveys Wnt5b (show WNT5B Proteins) signals in a directional manner during gastrulation.

Human RYK Receptor-Like Tyrosine Kinase (RYK) interaction partners

  1. results corroborated previous findings of Ryk-mediated Wnt5a (show WNT5A Proteins) effect, and suggested a role for Ror2 (show ROR2 Proteins) in the Wnt5a (show WNT5A Proteins) machinery in glioblastoma

  2. Early treatment with HGF (show HGF Proteins)/IgG complexes after myocardial ischaemia with reperfusion may rescue tissue through vasoprotection conferred by c-Met and RYK signalling

  3. Ryk-intracellular domain pathway may impair FOXO (show FOXO3 Proteins) protective activity in mutant polyglutamine neurons, suggesting neurons unable to efficiently maintain function and resist disease from the earliest phases of the pathogenic process in Huntington disease (show HTT Proteins)

  4. is a candidate wnt5a (show WNT5A Proteins) receptor.

  5. The Ryk is important for the Wnt-5a (show WNT5A Proteins)-dependent induction of MMP-2 (show MMP2 Proteins) and invasive activity in glioma-derived cells and that Ryk might have a novel patho-physiological function in adult cancer invasion.

  6. RYK and VANGL2 (show VANGL2 Proteins) proteins form a complex, whereas RYK also activated RhoA (show RHOA Proteins), a downstream effector of PCP (show PRCP Proteins) signaling.

  7. RYK interacts both physically and functionally with the E3 ubiquitin MIB1. MIB1 is sufficient to activate Wnt (show WNT2 Proteins)/CTNNB1 (show CTNNB1 Proteins) signaling and this activity depends on endogenous RYK.

  8. RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6.

Mouse (Murine) RYK Receptor-Like Tyrosine Kinase (RYK) interaction partners

  1. Ryk-intracellular domain pathway may impair FOXO (show FOXO3 Proteins) protective activity in mutant polyglutamine neurons, suggesting neurons unable to efficiently maintain function and resist disease from the earliest phases of the pathogenic process in Huntington disease (show HTT Proteins)

  2. Wnt5a (show WNT5A Proteins) regulates HSC (show FUT1 Proteins) quiescence and hematopoietic repopulation through the Ryk receptor and that this process is mediated by suppression of reactive oxygen species.

  3. Ryk inhibits axonal growth in response to Wnt5a (show WNT5A Proteins).

  4. Ryk is an important mediator of ventral midbrain dopaminergic neuron development.

  5. Ryk regulates Wnt5a (show WNT5A Proteins) signaling and planar cell polarity by modulating the degradation of Vangl2 (show VANGL2 Proteins).

  6. RYK and VANGL2 (show VANGL2 Proteins) proteins form a complex, whereas RYK also activated RhoA (show RHOA Proteins), a downstream effector of PCP (show BMP1 Proteins) signaling.

  7. Results identify Ryk as a multi-functional receptor that is able to transduce extrinsic cues into progenitor cells, promote GABAergic neuron formation, and inhibit oligodendrogenesis during ventral embryonic brain development.

  8. Mammalian Ryk, unlike the Drosophila Ryk homolog Derailed, functions as a coreceptor along with Frizzled for Wnt (show WNT2 Proteins) ligands.

  9. RYK regulates cell migration during mammalian cortical development through the binding to Eph (show EPHA1 Proteins) receptors

  10. Wnt3 (show WNT3 Proteins) repulsion is mediated by Ryk, expressed in a ventral-to-dorsal decreasing gradient

RYK Protein Profile

Protein Summary

The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with RYK

  • RYK receptor-like tyrosine kinase (RYK)
  • ryk receptor-like tyrosine kinase (ryk)
  • receptor-like tyrosine kinase (ryk)
  • receptor-like tyrosine kinase (RYK)
  • RYK receptor-like tyrosine kinase (ryk)
  • receptor-like tyrosine kinase (Ryk)
  • AW536699 protein
  • D3S3195 protein
  • ERK-3 protein
  • JTK5 protein
  • JTK5A protein
  • MGC114645 protein
  • RYK protein
  • RYK1 protein
  • Vik protein
  • wu:fb37b12 protein
  • wu:fi05b06 protein
  • zgc:158381 protein

Protein level used designations for RYK

RYK receptor-like tyrosine kinase , tyrosine kinase RYK , ryk receptor-like tyrosine kinase , receptor-like tyrosine kinase , tyrosine-protein kinase RYK , tyrosine kinase-related protein , tyrosine-protein kinase RYK-like , JTK5A protein tyrosine kinase , hydroxyaryl-protein kinase , NYK-R , growth factor receptor , kinase VIK , met-related kinase

GENE ID SPECIES
395409 Gallus gallus
470931 Pan troglodytes
477074 Canis lupus familiaris
550026 Xenopus (Silurana) tropicalis
558502 Danio rerio
718950 Macaca mulatta
734495 Xenopus laevis
781353 Bos taurus
100008628 Oryctolagus cuniculus
100466026 Ailuropoda melanoleuca
100541106 Meleagris gallopavo
100555132 Anolis carolinensis
100591428 Nomascus leucogenys
6259 Homo sapiens
20187 Mus musculus
140585 Rattus norvegicus
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