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anti-Zebrafish SHC1 antibody for Western Blotting

Recommended SHC1 Antibody (supplied by: Log in to see )

Antigen
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) Antibodies
  • p66
  • p66shc
  • P66shc
  • shc
  • SHC
  • Shc
  • SHC1
  • ShcA
  • SHCA
  • si:dkey-246i14.4
  • wu:fc10h03
Epitope
C-Term
41
39
17
15
13
13
13
10
9
9
8
8
7
6
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Xenopus laevis, Chicken, Dog (Canine), Zebrafish
216
170
131
9
5
5
2
1
1
1
Host
Rabbit
202
25
Clonality
Polyclonal
Conjugate
This SHC1 antibody is un-conjugated
7
7
6
5
5
5
5
5
5
5
5
5
1
1
1
Application
Western Blotting (WB)
166
78
60
56
49
33
8
7
6
4
3
1
1
Supplier
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Catalog No. ABIN928366
$ 473.93
Plus shipping costs $45.00

Similar anti-SHC1 Antibodies

Application / Reactivity Human Mouse (Murine) Dog (Canine) Rat (Rattus) Chicken Cow (Bovine) Xenopus laevis Zebrafish
Western Blotting (WB) 160 Antibodies 113 Antibodies 10 Antibodies 79 Antibodies 6 Antibodies 5 Antibodies 2 Antibodies 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 11 Antibodies 7 Antibodies 7 Antibodies 2 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 36 Antibodies 26 Antibodies 24 Antibodies
Immunohistochemistry (IHC) 81 Antibodies

General

Antigen SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) Antibodies
Epitope C-Term
(41), (39), (17), (15), (13), (13), (13), (10), (9), (9), (8), (8), (7), (6), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Xenopus laevis, Chicken, Dog (Canine), Zebrafish
(216), (170), (131), (9), (5), (5), (2), (1), (1), (1)
Host Rabbit
(202), (25)
Clonality
Polyclonal
Conjugate This SHC1 antibody is un-conjugated
(7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (1), (1), (1)
Application Western Blotting (WB)
(166), (78), (60), (56), (49), (33), (8), (7), (6), (4), (3), (1), (1)
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Product Details anti-SHC1 Antibody

Target Details SHC1 Application Details Handling Images
Cross-Reactivity Mouse (Murine), Rat (Rattus), Cow (Bovine), Frog, Chicken, Dog (Canine), Zebrafish (Brachydanio rerio)
Purification Purified
Immunogen SHC1 antibody was raised in rabbit using the C terminal of SHC1 as the immunogen

Target Details SHC1

Product Details anti-SHC1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SHC1 (SHC1 Antibody Abstract)
Background SHC1 is a signaling adapter that couples activated growth factor receptors to signaling pathway. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. Synonyms: Polyclonal SHC1 antibody, Anti-SHC1 antibody, SHC, Src homology 2 domain containing transforming protein 1 antibody, FLJ26504 antibody, SHC antibody, SHCA antibody, p52SHC antibody, p66 antibody, p66SHC antibody.
Research Area Cell Cycle, Apoptosis/Necrosis
Pathways RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-SHC1 Antibody Target Details SHC1 Handling Images back to top
Application Notes WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.
Comment

SHC1 Blocking Peptide, catalog no. 33R-1145, is also available for use as a blocking control in assays to test for specificity of this SHC1 antibody

Restrictions For Research Use only

Handling

Product Details anti-SHC1 Antibody Target Details SHC1 Application Details Images back to top
Format Lyophilized
Concentration 1 mg/mL
Buffer Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze/thaw cycles.
Storage RT/-20 °C
Storage Comment Store at 4 °C, following reconstitution, aliquot and store at -20 °C.