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anti-Mouse (Murine) SHC2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SHC2 Antibody (supplied by: Log in to see )

Antigen
SHC (Src Homology 2 Domain Containing) Transforming Protein 2 (SHC2) Antibodies
  • SCK
  • SHCB
  • SLI
  • 6720466E06
  • ShcB
  • Sli
  • SHC (Src homology 2 domain containing) transforming protein 2
  • SHC2
  • Shc2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
36
21
20
2
Host
Rabbit
29
6
4
Clonality
Polyclonal
Conjugate
This SHC2 antibody is conjugated to HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
21
13
9
3
3
3
2
1
Options
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Catalog No. ABIN1413314
$ 405.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1395421 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN1386708 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal

Similar anti-SHC2 Antibodies

Application / Reactivity Human Rat (Rattus) Mouse (Murine)
Western Blotting (WB) 21 Antibodies 8 Antibodies 6 Antibodies
Immunoprecipitation (IP) 2 Antibodies 2 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies 3 Antibodies 3 Antibodies
Immunohistochemistry (IHC) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies 13 Antibodies 13 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 2 Antibodies

General

Antigen SHC (Src Homology 2 Domain Containing) Transforming Protein 2 (SHC2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(36), (21), (20), (2)
Host Rabbit
(29), (6), (4)
Clonality
Polyclonal
Conjugate This SHC2 antibody is conjugated to HRP
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(21), (13), (9), (3), (3), (3), (2), (1)
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Product Details anti-SHC2 Antibody

Target Details SHC2 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human SHC2/Sck
Isotype IgG

Target Details SHC2

Product Details anti-SHC2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Shc2/Sck (SHC2 Antibody Abstract)
Background

Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events (1). Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain (2,3). Human Sck transcripts are present at high levels in liver, pancreas, prostate and ovary (4,5). In vascular endothelial cells, Sck participates in VEGF-induced signal transduction (6). Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation (7,8).


Synonyms: Protein Sck, SCK, SH2 domain protein C2, SHC transforming protein 2, SHCB, Src homology 2 domain containing transforming protein C2, SHC2_HUMAN.
Pathways RTK Signaling, Neurotrophin Signaling Pathway

Application Details

Product Details anti-SHC2 Antibody Target Details SHC2 Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only

Handling

Product Details anti-SHC2 Antibody Target Details SHC2 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Preservative Gentamicin sulfate
Precaution of Use This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Storage -20 °C
Storage Comment Store at 4°C
Expiry Date 12 months