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anti-Human SOS1 antibody for Immunocytochemistry

Recommended SOS1 Antibody (supplied by: Log in to see )

Antigen
Son of Sevenless Homolog 1 (Drosophila) (SOS1) Antibodies
  • 4430401P03Rik
  • 9630010N06
  • AI449023
  • GF1
  • GGF1
  • GINGF
  • HGF
  • NS4
Reactivity
Human
49
28
9
7
3
1
1
1
1
1
1
Host
Mouse
34
17
7
Clonality
Monoclonal
Conjugate
This SOS1 antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
42
22
21
13
6
5
3
1
1
Supplier
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Available images

Catalog No. ABIN259057
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010194078 ABIN4355179 ICC IF WB DyLight 350 Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355180 ICC IF WB DyLight 405 Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355181 ICC IF WB PE Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355182 ICC IF WB PerCP Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355183 ICC IF WB Allophycocyanin Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355184 ICC IF WB DyLight 755 Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355185 ICC IF WB DyLight 680 Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355186 ICC IF WB DyLight 488 Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355187 ICC IF WB DyLight 405LS Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355188 ICC IF WB Alexa Fluor 405 Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355189 ICC IF WB Alexa Fluor 488 Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355190 ICC IF WB Alexa Fluor 647 Mouse IgG1 Log in to see SOS-01
0.0010194078 ABIN4355191 ICC IF WB Alexa Fluor 700 Mouse IgG1 Log in to see SOS-01

Similar anti-SOS1 Antibodies

Application / Reactivity Human
ELISA 16 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunocytochemistry (ICC) 14 Antibodies
Immunofluorescence (IF) 23 Antibodies
Immunohistochemistry (IHC) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 39 Antibodies

General

Antigen Son of Sevenless Homolog 1 (Drosophila) (SOS1) Antibodies
Reactivity Human
(49), (28), (9), (7), (3), (1), (1), (1), (1), (1), (1)
Host Mouse
(34), (17), (7)
Clonality (Clone)
Monoclonal   ( )
Conjugate This SOS1 antibody is un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(42), (22), (21), (13), (6), (5), (3), (1), (1)
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Product Details anti-SOS1 Antibody

Target Details SOS1 Application Details Handling Images
Specificity The SOS-01 reacts with human Sos, an ubiquitously expressed 150 kDa intracellular protein.
Cross-Reactivity (Details) Not yet tested in other species.
Purification Protein A purified
Immunogen Peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human Sos protein (NM_005633.3)
Clone SOS-01
Isotype IgG1

Target Details SOS1

Product Details anti-SOS1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SOS1 (SOS1 Antibody Abstract)
Background The guanine nucleotide exchange factor Sos (Son-of-sevenless) is a complexmultidomain protein that activates the small GTPase Ras (H-Ras, K-Ras, N-Ras, but notfunctionally distinct R-Ras) in response to receptor tyrosine kinase stimulation.Nucleotide exchange activity of Sos is stimulated by allosteric Ras binding. By another(separable) guanine exchange factor domain domain Sos modulates activity of Rac/RhoGTPases. Sos thus integrates signals that affect both gene expression and cytoskeletalreorganization, the Sos-mediated Ras-activation and Rac activation differ in compositionand stability of the formed complex. Alternate Names: anti-GF1 antibody, anti-GGF1 antibody, anti-GINGF antibody, anti-HGF antibody.
Gene Symbol: SOS1
Gene ID 6654
NCBI Accession NM_005633
Research Area Cancer
Pathways RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-SOS1 Antibody Target Details SOS1 Handling Images back to top
Application Notes WB: Use under reducing conditions. Antibody purity is > 95% (by SDS-PAGE).
Recommended dilutions: Western Blot 1 µg/mL, Immunocytochemistry/Immunofluorescence 1:10-1:2000
Restrictions For Research Use only

Handling

Product Details anti-SOS1 Antibody Target Details SOS1 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.

Images

Product Details anti-SOS1 Antibody Target Details SOS1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-SOS1 antibody (Son of Sevenless Homolog 1 (Drosophila)) (ABIN259057) anti-Son of Sevenless Homolog 1 (Drosophila) (SOS1) antibody