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Son of Sevenless Homolog 2 (Drosophila) ELISA Kits (SOS2)
On are 0 Son of Sevenless Homolog 2 (Drosophila) (SOS2) ELISA Kits from different suppliers available. Additionally we are shipping SOS2 Antibodies (41) and SOS2 Proteins (3) and many more products for this protein. A total of 49 SOS2 products are currently listed.
mSOS-2, SOS-2, Sos1
list all ELISA KIts Gene Name GeneID UniProt
Rat SOS2 SOS2 85384  
Human SOS2 SOS2 6655 Q07890
Mouse SOS2 SOS2 20663  

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Human Son of Sevenless Homolog 2 (Drosophila) (SOS2) interaction partners

  1. Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome

  2. We identified two novel genes, SOS2 and LZTR1 (show LZTR1 ELISA Kits), associated with Noonan syndrome, thereby expanding the molecular spectrum of RASopathies.

  3. multicenter pharmacogenetic study in children (ages 6-11): Data suggest that SNP in SOS2 (rs13379306) in children with growth hormone (show GH1 ELISA Kits) deficiency is associated with drug resistance to hormone replacement therapy with recombinant human growth hormone (show GH1 ELISA Kits).

  4. intracellular Francisella tularensis novicida triggers temporal and early activation of Ras through the SOS2/GrB2/PKCalpha/PKCbetaI quaternary complex; Ras signalling by intracellular F. tularensis is essential for intracellular proliferation in the cytosol

  5. Significant association of single nucleotide polymorphism within three genes--PPARgamma (show PPARG ELISA Kits), SOS2, and PCK1 (show PCK1 ELISA Kits)--with Alzheimer's disease, was confirmed.

  6. Loss of MADD (show ETFA ELISA Kits) expression resulted in reduced Grb2 (show GRB2 ELISA Kits) and Sos1 (show SOS1 ELISA Kits)/2 recruitment to the TNFR1 (show TNFRSF1A ELISA Kits) complex and decreased Ras and MEKK1 (show MAP3K1 ELISA Kits)/2 activation

Mouse (Murine) Son of Sevenless Homolog 2 (Drosophila) (SOS2) interaction partners

  1. The increased activity of the PI3K/AKT (show AKT1 ELISA Kits) pathway led to downregulation of the surface receptor CD62L (show SELL ELISA Kits) in Sos-1 (show SOS1 ELISA Kits)/2dKO T cells and a subsequent impairment in T-cell migration.

  2. Absolute counts of mature B and T cells in spleen and peripheral blood were unchanged in single-knockout mutants, while significantly reduced in Sos1 (show SOS1 ELISA Kits)/2 double-knockout mice.

  3. assessed the independent and combined roles for the RasGEFs Sos1 (show SOS1 ELISA Kits), Sos2, and RasGRP1 (show RASGRP1 ELISA Kits) during thymocyte development

  4. Vav1 (show VAV1 ELISA Kits) transduces TCR signals to Ras by controlling recruitment of RasGRP1 (show RASGRP1 ELISA Kits) to the membrane and recruitment of Sos1 (show SOS1 ELISA Kits) and -2 to the transmembrane adapter protein (show GRB10 ELISA Kits) LAT (show LAT ELISA Kits).

  5. Sos2 is dispensable for both NMDA-induced Erk (show EPHB2 ELISA Kits) activation in cortical neuron cultures from neonatal mice, and for LTP (show SCP2 ELISA Kits) induction at the Schaffer-CA1 (show CA1 ELISA Kits) synapses in brain slices from young mice that is known to require NMDA receptor signaling.

SOS2 Antigen Profile

Antigen Summary

mRNA expression increases after chronic clozapine treatment in the prefrontal cortex\\; may play a role in synaptic function

Alternative names and synonyms associated with SOS2

  • son of sevenless homolog 2 (Drosophila) (Sos2) Elisa Kit
  • son of sevenless homolog 2 (Drosophila) (SOS2) Elisa Kit
  • mSOS-2 Elisa Kit
  • SOS-2 Elisa Kit
  • Sos1 Elisa Kit

Protein level used designations for SOS2

son of sevenless homolog 2 , son of sevenless 1 , SOS-2 , guanine nucleotide exchange factor , guanine nucleotide releasing factor

85384 Rattus norvegicus
6655 Homo sapiens
20663 Mus musculus
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