anti-Human TEK antibody for Enzyme Immunoassay

Recommended TEK Antibody (supplied by: Log in to see )

Antigen
TEK Tyrosine Kinase, Endothelial (TEK) Antibodies
  • TEK
  • DKFZp469E064
  • AA517024
  • Cd202b
  • Hyk
  • Tie2
  • tie-2
  • CD202B
  • TIE-2
  • TIE2
  • VMCM
  • VMCM1
  • Tie-2
  • tie2
  • TEK tyrosine kinase, endothelial
  • endothelial-specific receptor tyrosine kinase
  • TEK
  • LOC100356675
  • tek
  • Tek
Epitope
pTyr1113
29
27
24
23
22
19
16
15
14
14
14
11
10
7
6
6
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
349
167
85
7
6
3
1
Host
Rabbit
200
155
35
4
3
2
Clonality
Polyclonal
Conjugate
This TEK antibody is un-conjugated
27
21
18
15
12
11
9
7
6
6
6
6
5
5
5
5
4
4
4
4
4
4
4
4
4
4
3
3
2
Application
Enzyme Immunoassay (EIA)
237
180
140
121
53
50
42
33
22
13
7
7
5
4
4
4
3
2
1
1
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Catalog No. ABIN358489
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN155164 EIA FACS WB Biotin Mouse IgG1 Extracellular Domain Log in to see Cl-9 3
1 ABIN155163 EIA FACS WB Biotin Mouse IgG1 Extracellular Domain Log in to see Cl-2 3
1 ABIN155165 EIA FACS WB Biotin Mouse IgG1 Log in to see Cl-16 4
1 ABIN115155 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Log in to see Cl-2 4
1 ABIN115157 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Log in to see Cl-9 4
1 ABIN115159 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Log in to see Cl-16 4
1 ABIN951223 EIA IHC (p) Rabbit IgG C-Term Log in to see Polyclonal

Top referenced anti-TEK antibody for Enzyme Immunoassay

Similar anti-TEK Antibodies

Application / Reactivity Human
Cell Culture (CC) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 3 Antibodies
Dot Blot (DB) 16 Antibodies
ELISA 167 Antibodies
Enzyme Immunoassay (EIA) 8 Antibodies
Flow Cytometry (FACS) 113 Antibodies
Functional Studies (Func) 3 Antibodies
Immunocytochemistry (ICC) 19 Antibodies
Immunofluorescence (IF) 26 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 4 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 53 Antibodies
Immunohistochemistry (IHC) 99 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 38 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Intracellular Staining (ICS) 4 Antibodies
Mass Cytometry (CyTOF) 1 Antibodies

General

Antigen TEK Tyrosine Kinase, Endothelial (TEK) Antibodies
Epitope pTyr1113
(29), (27), (24), (23), (22), (19), (16), (15), (14), (14), (14), (11), (10), (7), (6), (6), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(349), (167), (85), (7), (6), (3), (1)
Host Rabbit
(200), (155), (35), (4), (3), (2)
Clonality
Polyclonal
Conjugate This TEK antibody is un-conjugated
(27), (21), (18), (15), (12), (11), (9), (7), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2)
Application Enzyme Immunoassay (EIA)
(237), (180), (140), (121), (53), (50), (42), (33), (22), (13), (7), (7), (5), (4), (4), (4), (3), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-TEK Antibody

Target Details TEK Application Details Handling ProductDetails: References for anti-TEK antibody (ABIN358489) Images
Specificity This antibody detects TEK pTyr1113. Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).
Purification Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1113 of human TEK.
Isotype Ig

Target Details TEK

Product Details anti-TEK Antibody Application Details Handling ProductDetails: References for anti-TEK antibody (ABIN358489) Images back to top
Antigen
Alternative Name CD202b / TEK (TEK Antibody Abstract)
Background The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK
Molecular Weight 125810 Da
Gene ID 83659, 9606
UniProt Q02763
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling, Growth Factor Binding

Application Details

Product Details anti-TEK Antibody Target Details TEK Handling ProductDetails: References for anti-TEK antibody (ABIN358489) Images back to top
Application Notes ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TEK Antibody Target Details TEK Application Details ProductDetails: References for anti-TEK antibody (ABIN358489) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-TEK antibody (ABIN358489)

Product Details anti-TEK Antibody Target Details TEK Application Details Handling Images back to top
Background publications

Cascone, Audero, Giraudo, Napione, Maniero, Philips, Collard, Serini, Bussolino: "Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1." in: Blood, Vol. 102, Issue 7, pp. 2482-90, 2003

DeBusk, Chen, Nishishita, Chen, Thomas, Lin: "Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis." in: Arthritis and rheumatism, Vol. 48, Issue 9, pp. 2461-71, 2003

Poncet, Gasc, Janzer, Meyer, Juillerat-Jeanneret: "Expression of Tie-2 in human peripheral and autonomic nervous system." in: Neuropathology and applied neurobiology, Vol. 29, Issue 4, pp. 361-9, 2003

Lee, Koh: "Shear stress activates Tie2 receptor tyrosine kinase in human endothelial cells." in: Biochemical and biophysical research communications, Vol. 304, Issue 2, pp. 399-404, 2003

Sussman, Upalakalin, Roberts, Kocher, Benjamin: "Blood markers for vasculogenesis increase with tumor progression in patients with breast carcinoma." in: Cancer biology & therapy, Vol. 2, Issue 3, pp. 255-6, 2003

Images

Product Details anti-TEK Antibody Target Details TEK Application Details Handling ProductDetails: References for anti-TEK antibody (ABIN358489) back to top
Supplier Images
 image for anti-TEK antibody (TEK Tyrosine Kinase, Endothelial) (pTyr1113) (ABIN358489) anti-TEK Tyrosine Kinase, Endothelial (TEK) (pTyr1113) antibody