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anti-Human TEK antibody for Immunohistochemistry (Frozen Sections)

Recommended TEK Antibody (supplied by: Log in to see )

Antigen
TEK Tyrosine Kinase, Endothelial (TEK) Antibodies
  • AA517024
  • CD202B
  • Cd202b
  • DKFZp469E064
  • Hyk
  • TEK
  • Tie-2
  • TIE-2
  • tie-2
  • TIE2
  • tie2
  • Tie2
  • VMCM
  • VMCM1
Epitope
Extracellular Domain
29
24
22
21
20
19
17
14
14
13
10
7
7
6
6
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
320
151
71
6
6
2
2
1
Host
Mouse
191
134
38
3
2
2
Clonality
Monoclonal
Conjugate
This TEK antibody is un-conjugated
23
19
16
14
11
11
8
6
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
231
179
127
67
47
46
45
38
20
11
9
7
4
4
3
2
1
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Catalog No. ABIN967565
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088295416 ABIN115155 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Log in to see Cl-2 4
0.00088295416 ABIN115159 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Log in to see Cl-16 4
0.00088295416 ABIN115157 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Log in to see Cl-9 4
0.00088295416 ABIN204823 IHC (fro) IHC (p) WB Rabbit IgG pTyr1100 Log in to see Polyclonal
0.00088295416 ABIN1863205 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 1-116 Log in to see Polyclonal
0.00088295416 ABIN1980519 ICC IHC (fro) IHC (p) ELISA WB Rabbit AA 286-465 Log in to see Polyclonal

Top referenced anti-TEK antibody for Immunohistochemistry (Frozen Sections)

Similar anti-TEK Antibodies

Application / Reactivity Mouse (Murine) Human
Dot Blot (DB) 4 Antibodies 16 Antibodies
ELISA 30 Antibodies 176 Antibodies
ELISA (Detection) 4 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 9 Antibodies
Flow Cytometry (FACS) 32 Antibodies 102 Antibodies
Functional Studies (Func) 1 Antibodies
Immunocytochemistry (ICC) 14 Antibodies
Immunofluorescence (IF) 21 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 45 Antibodies
Immunohistochemistry (IHC) 33 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 36 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Intracellular Staining (ICS) 4 Antibodies
Western Blotting (WB) 73 Antibodies

General

Antigen TEK Tyrosine Kinase, Endothelial (TEK) Antibodies
Epitope Extracellular Domain
(29), (24), (22), (21), (20), (19), (17), (14), (14), (13), (10), (7), (7), (6), (6), (5), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(320), (151), (71), (6), (6), (2), (2), (1)
Host Mouse
(191), (134), (38), (3), (2), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TEK antibody is un-conjugated
(23), (19), (16), (14), (11), (11), (8), (6), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(231), (179), (127), (67), (47), (46), (45), (38), (20), (11), (9), (7), (4), (4), (3), (2), (1)
Pubmed 4 references available
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Product Details anti-TEK Antibody

Target Details TEK Application Details Handling References for anti-TEK Antibody (ABIN967565) Images
Brand BD Pharmingen™
Cross-Reactivity Mouse (Murine)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3. Please refer to us for technical protocols.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human TIE2 extracellular domain Recombinant Protein
Clone 33
Isotype IgG1, kappa

Target Details TEK

Product Details anti-TEK Antibody Application Details Handling References for anti-TEK Antibody (ABIN967565) Images back to top
Antigen
Alternative Name TIE2 (TEK Antibody Abstract)
Background The TIE receptor family is a member of the class of receptors called the receptor tyrosine kinases (RKT). RKTs are cell surface receptors which also contain a protein kinase domain in their intracellular portion and upon binding of their specific growth factor, initiate a series of downstream biological events. TIE receptors, designated Tie1 and Tie2 (Tek) have a tissue distribution which is limited primarily to cells of endothelial origin. Tie2 has been shown to be required for the normal development of vascular structures during embryogenesis. It has also been demonstrated to play a role in normal and pathological angiogenesis in adults. Tie2 has a predicted molecular weight of 126 kD, but may be observable at ~130-165 kDa. This antibody has been reported to recognize human and mouse Tie2 but not Tie1.
Molecular Weight 130-165 kDa
Research Area Organogenesis, Tyrosine Kinases
Pathways RTK Signaling

Application Details

Product Details anti-TEK Antibody Target Details TEK Handling References for anti-TEK Antibody (ABIN967565) Images back to top
Comment

Related Products: ABIN967389, ABIN968537

Restrictions For Research Use only

Handling

Product Details anti-TEK Antibody Target Details TEK Application Details References for anti-TEK Antibody (ABIN967565) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.

References for anti-TEK Antibody (ABIN967565)

Product Details anti-TEK Antibody Target Details TEK Application Details Handling Images back to top
Product cited in:

Partanen, Dumont: "Functions of Tie1 and Tie2 receptor tyrosine kinases in vascular development." in: Current topics in microbiology and immunology, Vol. 237, Issue 4, pp. 159-72, 1999

Peters, Coogan, Berry, Marks, Iglehart, Kontos, Rao, Sankar, Trogan: "Expression of Tie2/Tek in breast tumour vasculature provides a new marker for evaluation of tumour angiogenesis." in: British journal of cancer, Vol. 77, Issue 1, pp. 51-6, 1998

Wong, Haroon, Werner, Dewhirst, Greenberg, Peters: "Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues." in: Circulation research, Vol. 81, Issue 4, pp. 567-74, 1997

Dumont, Gradwohl, Fong, Puri, Gertsenstein, Auerbach, Breitman: "Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo." in: Genes & development, Vol. 8, Issue 16, pp. 1897-909, 1994

Images

Product Details anti-TEK Antibody Target Details TEK Application Details Handling References for anti-TEK Antibody (ABIN967565) back to top
Supplier Images
Western Blotting (WB) image for anti-TEK antibody (TEK Tyrosine Kinase, Endothelial) (Extracellular Domain) (ABIN967565) Western blot analysis for Tie2. Human endothelial cell lysates were probed with the m...