Browse our anti-TRKA (NTRK1) Antibodies

Full name:
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 Antibodies (NTRK1)
On www.antibodies-online.com are 452 Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) Antibodies from 32 different suppliers available. Additionally we are shipping TRKA Kits (37) and TRKA Proteins (29) and many more products for this protein. A total of 542 TRKA products are currently listed.
Synonyms:
C80751, CAPM1, CFTD, CTRKA, hscp30, MTC, NEM1, OK/SW-cl.5, p140-TrkA, Tkr, TM-5, TM3, TM5, TM30, TM30nm, TPMsk3, Trk, Trk-A, TRK1, trkA
list all antibodies Gene Name GeneID UniProt
NTRK1 4914 P04629
NTRK1 18211 Q3UFB7
NTRK1 59109 P35739

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Top referenced anti-TRKA Antibodies

  1. Human Polyclonal TRKA Primary Antibody for EIA, WB - ABIN358249 : Tacconelli, Farina, Cappabianca, Desantis, Tessitore, Vetuschi, Sferra, Rucci, Argenti, Screpanti, Gulino, Mackay: TrkA alternative splicing: a regulated tumor-promoting switch in human neuroblastoma. in Cancer cell 2004 (PubMed)
    Show all 5 references for 358249

  2. Human Polyclonal TRKA Primary Antibody for EIA, WB - ABIN453859 : Tokusashi, Asai, Tamakawa, Yamamoto, Yoshie, Yaginuma, Miyokawa, Aoki, Kino, Kasai, Ogawa: Expression of NGF in hepatocellular carcinoma cells with its receptors in non-tumor cell components. in International journal of cancer. Journal international du cancer 2005 (PubMed)
    Show all 5 references for 453859

  3. Human Polyclonal TRKA Primary Antibody for EIA, WB - ABIN359950 : Schulte, Schramm, Klein-Hitpass, Klenk, Wessels, Hauffa, Eils, Eils, Brodeur, Schweigerer, Havers, Eggert: Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas. in Oncogene 2005 (PubMed)
    Show all 4 references for 359950

  4. Human Polyclonal TRKA Primary Antibody for IF - ABIN401580 : Wiese, Jablonka, Holtmann, Orel, Rajagopal, Chao, Sendtner: Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 3 references for 401580

  5. Human Monoclonal TRKA Primary Antibody for ICC, ELISA - ABIN969444 : Geetha, Wooten: TrkA receptor endolysosomal degradation is both ubiquitin and proteasome dependent. in Traffic (Copenhagen, Denmark) 2008 (PubMed)
    Show all 2 references for 969444

  6. Human Polyclonal TRKA Primary Antibody for IHC (p), IP - ABIN127050 : Segal, Greenberg: Intracellular signaling pathways activated by neurotrophic factors. in Annual review of neuroscience 1997 (PubMed)
    Show all 2 references for 127050

  7. Human Monoclonal TRKA Primary Antibody for FACS - ABIN4897415 : Paczkowska, Kaczy?ska, Pius-Sadowska, Rogi?ska, Kawa, Ustianowski, Safranow, Celewicz, Machali?ski: Humoral activity of cord blood-derived stem/progenitor cells: implications for stem cell-based adjuvant therapy of neurodegenerative disorders. in PLoS ONE 2014 (PubMed)

  8. Human Polyclonal TRKA Primary Antibody for IF (p), IHC (p) - ABIN726110 : Li, Shen, Di, Li, Geng, Lu, He: Biological and clinical significance of p75NTR expression in laryngeal squamous epithelia and laryngocarcinoma. in Acta oto-laryngologica 2012 (PubMed)

  9. Human Polyclonal TRKA Primary Antibody for IF (p), IHC (p) - ABIN703330 : Ullrich, Weber, Post, Popp, Grein, Zechner, Guerrero González, Kreis, Schmitt, Üçeyler, Lesch, Schuh: OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency. in Molecular psychiatry 2017 (PubMed)

  10. Human Monoclonal TRKA Primary Antibody for FACS - ABIN4897419 : Foveau, Ancot, Leroy, Petrelli, Reiss, Vingtdeux, Giordano, Fafeur, Tulasne: Down-regulation of the met receptor tyrosine kinase by presenilin-dependent regulated intramembrane proteolysis. in Molecular biology of the cell 2009 (PubMed)

More Antibodies against TRKA Interaction Partners

Zebrafish Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) interaction partners

  1. By immunohistochemistry, the localization of Neurotrophinss has been observed mainly in Purkinje cells; TrkA and TrkB (show NTRK2 Antibodies)-receptors in cells and fibers of granular and molecular layers. TrkC (show NTRK3 Antibodies) was faintly detected

  2. TrkA-like immunoreactivity was the only Trk detected, and it was restricted to the somata of crypt sensory neurons, their central processes being apparently unreactive.

Rabbit Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) interaction partners

  1. report describing differential expression of proteins and mRNA for NGF (show NGFB Antibodies) and its cognate receptors, NTRK1 and NGFR (show NGFR Antibodies), in the male sex organs of rabbits

Human Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) interaction partners

  1. analysis of NTRK1 transcripts in peripheral blood cells of the patient revealed an influence of the variant on mRNA splicing. The C>A transversion generated a novel splice-site, which led to the incorporation of 10 intronic bases into the NTRK1 mRNA and consequently to a non-functional gene product.

  2. A novel nonsense mutation and a known splice-site mutation were detected in NTRK1 in two siblings and were shown to be associated with congenital insensitivity to pain with anhidrosis.

  3. NT3 (show NTF3 Antibodies) upregulates cellular proliferation, extracellular matrix protein production, and collagen deposition in human aortic valve interstitial cells through the Trk-Akt (show AKT1 Antibodies)-cyclin D1 (show CCND1 Antibodies) cascade.

  4. NTRK1 gene fusion in spitzoid neoplasms results in tumors with Kamino bodies and were typically arranged in smaller nests with smaller predominantly spindle-shaped cells, occasionally forming rosettes.

  5. expression levels of tropomyosin 3 (TPM3 (show TPM3 Antibodies)) were higher in stage III ESCC tissue compared with stage I (P<0.05). The findings of the present study identified twelve proteins, which are closely associated with ESCC invasion and metastasis, apoptosis and cell signal transduction.

  6. Results suggest that NTRK1 oncogenic activation through gene fusion defines a novel and distinct subset of soft tissue tumors resembling lipofibromatosis (LPF), but displaying cytologic atypia and a neural immunophenotype, provisionally named LPF-like neural tumors.

  7. This review highlights treatment options, including clinical trials for ROS1 rearrangement, RET fusions, NTRK1 fusions, MET exon skipping, BRAF mutations, and KRAS mutations.

  8. ShcD (show SHC4 Antibodies) binds to active Ret (show RET Antibodies), TrkA, and TrkB (show NTRK2 Antibodies) neurotrophic factor (show NTF3 Antibodies) receptors predominantly via its phosphotyrosine-binding (PTB (show PTBP1 Antibodies)) domain.

  9. Based on these current developments, the present review provides not only a broad overview of the biological effects of NGF-TrkA-p75NTR on cancer cells and their microenvironment, but also explains why NGF and its receptors are going to evoke major interest as promising therapeutic anti-cancer targets in the coming decade.

  10. TrkA misfolding and aggregation induced by some Insensitivity to Pain with Anhidrosis mutations disrupt the autophagy homeostasis causing neurodegeneration.

Mouse (Murine) Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) interaction partners

  1. These findings suggest that by interacting with PlexA4 (show PLXNA4 Antibodies), TrkA plays a crucial role in redirecting local Sema3A (show SEMA3A Antibodies) signaling to retrograde axonal transport, thereby regulating dendritic GluA2 (show GRIA2 Antibodies) localization and patterning.

  2. proposal that KIF1A (show KIF1A Antibodies) is essential for the survival and function of sensory neurons because of the TrkA transport and its synergistic support of the NGF (show NGFB Antibodies)/TrkA/PI3K signaling pathway

  3. As a result, overexpression of PTP (show SLC25A3 Antibodies)-MEG2 (show PTPN9 Antibodies) down-regulates NGF (show NGFB Antibodies)/TrkA signaling and blocks neurite outgrowth and differentiation

  4. TrkA misfolding and aggregation induced by some Insensitivity to Pain with Anhidrosis mutations disrupt the autophagy homeostasis causing neurodegeneration.

  5. USP36 (show USP36 Antibodies) actions extend beyond TrkA because the presence of USP36 (show USP36 Antibodies) interferes with Nedd4-2 (show NEDD4L Antibodies)-dependent Kv7.2 (show KCNQ2 Antibodies)/3 channel regulation.

  6. functional PAP (show ASAP1 Antibodies)(thorn) neurons are essential for the analgesic effect, which is mediated by NGF (show NGFB Antibodies)-trkA signaling.

  7. Dimeric dipeptide mimetics of the nerve growth factor Loop 4 and Loop 1 activate TRKA with different patterns of intracellular signal transduction.

  8. Data show that lysophosphatidic acid (LPA) induces phosphorylation of trkA receptor (TrkA) through lysophosphatidic acid receptor 1 (LPA1 (show LPAR1 Antibodies)) binding to TrkA

  9. adult homozygous TrkAC knock-in mice displayed severe deficits in acute and tissue injury-induced pain, representing the first viable adult Trk mouse mutant with a pain phenotype

  10. IL-6 (show IL6 Antibodies) may act as a new potential cumulus expansion-related transcript, which may be involved in the integration of TrkA and EGF (show EGF Antibodies) signaling in affecting expansion of cumulus oocyte complexes.

TRKA (NTRK1) Antigen Profile

Antigen Summary

This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TRKA (NTRK1)

  • neurotrophic tyrosine kinase, receptor, type 1 (ntrk1) antibody
  • neurotrophic tyrosine kinase, receptor, type 1 (NTRK1) antibody
  • neurotrophic tyrosine kinase, receptor, type 1 (LOC100354292) antibody
  • neurotrophic tyrosine kinase, receptor, type 1 (Ntrk1) antibody
  • tropomyosin 3 (TPM3) antibody
  • C80751 antibody
  • CAPM1 antibody
  • CFTD antibody
  • CTRKA antibody
  • hscp30 antibody
  • MTC antibody
  • NEM1 antibody
  • OK/SW-cl.5 antibody
  • p140-TrkA antibody
  • Tkr antibody
  • TM-5 antibody
  • TM3 antibody
  • TM5 antibody
  • TM30 antibody
  • TM30nm antibody
  • TPMsk3 antibody
  • Trk antibody
  • Trk-A antibody
  • TRK1 antibody
  • trkA antibody

Protein level used designations for NTRK1

high affinity nerve growth factor receptor , tyrosine kinase receptor A , neurotrophic tyrosine kinase, receptor, type 1 , high affinity nerve growth factor receptor-like , tropomyosin-related kinase A , Oncogene TRK , TRK1-transforming tyrosine kinase protein , gp140trk , TrkA neurotrophin receptor , p140-TrkA , slow nerve growth factor receptor , trk , trk-A , trkA proto-oncogene receptor , neurotrophic tyrosine kinase receptor type 1 , tropomyosin receptor kinase , alpha-tropomyosin, slow skeletal , cytoskeletal tropomyosin TM30 , heat-stable cytoskeletal protein 30 kDa , tropomyosin alpha-3 chain , tropomyosin gamma , tropomyosin-5

GENE ID SPECIES
30546 Danio rerio
719670 Macaca mulatta
100064594 Equus caballus
100452269 Pongo abelii
100474165 Ailuropoda melanoleuca
457408 Pan troglodytes
490404 Canis lupus familiaris
100354292 Oryctolagus cuniculus
100585466 Nomascus leucogenys
100618744 Monodelphis domestica
4914 Homo sapiens
18211 Mus musculus
59109 Rattus norvegicus
353111 Bos taurus
396337 Gallus gallus
7170 Homo sapiens
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