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anti-Human TRKA antibody for Immunocytochemistry

Recommended TRKA Antibody (supplied by: Log in to see )

Antigen
Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) Antibodies
  • trk
  • trka
  • TRKA
  • MTC
  • TRK
  • TRK1
  • Trk-A
  • p140-TrkA
  • C80751
  • Tkr
  • TrkA
  • Trk
  • CTRKA
  • trkA
  • CAPM1
  • CFTD
  • NEM1
  • OK/SW-cl.5
  • TM-5
  • TM3
  • TM30
  • TM30nm
  • TM5
  • TPMsk3
  • hscp30
  • neurotrophic tyrosine kinase, receptor, type 1
  • tropomyosin 3
  • ntrk1
  • NTRK1
  • LOC100354292
  • Ntrk1
  • TPM3
Epitope
AA 33-423
48
22
22
18
17
16
15
15
15
15
13
13
12
12
12
10
10
10
8
8
7
7
6
6
6
6
5
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
398
240
196
2
2
Host
Mouse
362
62
4
4
2
Clonality
Monoclonal
Conjugate
This TRKA antibody is un-conjugated
16
15
15
11
9
9
8
8
8
8
8
7
7
7
7
7
6
2
2
2
2
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
250
143
88
88
68
51
49
39
19
8
5
5
4
2
1
Options
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Catalog No. ABIN969444
$ 393.80
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2737768 ICC FACS IP IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2869408 ELISA ICC WB Mouse IgG1 AA 33-423 Log in to see 6B2
1 ABIN307200 ICC IP WB Rabbit IgG Extracellular Domain Log in to see Polyclonal
1 ABIN4362566 ELISA ICC IF WB Mouse IgG1 Log in to see 6B2
1 ABIN4362565 ICC IF IP WB Rabbit pTyr490 Log in to see Polyclonal
1 ABIN241927 ICC IP WB Rabbit pTyr490 Log in to see Polyclonal
1 ABIN3015035 ICC FACS IP IHC WB Rabbit Log in to see Polyclonal

Top referenced anti-TRKA antibody for Immunocytochemistry

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Application / Reactivity Human
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Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 67 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Immunofluorescence (IF) 49 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 88 Antibodies
Immunohistochemistry (IHC) 81 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 50 Antibodies
Immunoprecipitation (IP) 37 Antibodies
Neutralization (Neut) 2 Antibodies
Western Blotting (WB) 225 Antibodies

General

Antigen Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) Antibodies
Epitope AA 33-423
(48), (22), (22), (18), (17), (16), (15), (15), (15), (15), (13), (13), (12), (12), (12), (10), (10), (10), (8), (8), (7), (7), (6), (6), (6), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(398), (240), (196), (2), (2)
Host Mouse
(362), (62), (4), (4), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TRKA antibody is un-conjugated
(16), (15), (15), (11), (9), (9), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (6), (2), (2), (2), (2), (1), (1)
Application Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(250), (143), (88), (88), (68), (51), (49), (39), (19), (8), (5), (5), (4), (2), (1)
Pubmed 2 references available
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Product Details anti-TRKA Antibody

Target Details TRKA Application Details Handling References for anti-TRKA Antibody (ABIN969444) Images
Purification Ascites
Immunogen Purified recombinant extracellular fragment of human TrkA (AA 33-423) fused with hIgGFc tag expressed in HEK293 cell line.
Clone 6B2
Isotype IgG1

Target Details TRKA

Product Details anti-TRKA Antibody Application Details Handling References for anti-TRKA Antibody (ABIN969444) Images back to top
Antigen
Alternative Name TrkA (NTRK1 Antibody Abstract)
Background TrkA, also known as NTRK1, MTC, TRK, TRK1. It is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Molecular Weight 87.4 kDa
Gene ID 4914
HGNC 4914
Research Area Cancer
Pathways RTK Signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process

Application Details

Product Details anti-TRKA Antibody Target Details TRKA Handling References for anti-TRKA Antibody (ABIN969444) Images back to top
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Product Details anti-TRKA Antibody Target Details TRKA Application Details References for anti-TRKA Antibody (ABIN969444) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.

References for anti-TRKA Antibody (ABIN969444)

Product Details anti-TRKA Antibody Target Details TRKA Application Details Handling Images back to top
Product cited in:

Geetha, Wooten: "TrkA receptor endolysosomal degradation is both ubiquitin and proteasome dependent." in: Traffic (Copenhagen, Denmark), Vol. 9, Issue 7, pp. 1146-56, 2008

Schulte, Kuhfittig-Kulle, Klein-Hitpass, Schramm, Biard, Pfeiffer, Eggert: "Expression of the TrkA or TrkB receptor tyrosine kinase alters the double-strand break (DSB) repair capacity of SY5Y neuroblastoma cells." in: DNA repair, Vol. 7, Issue 10, pp. 1757-64, 2008

Images

Product Details anti-TRKA Antibody Target Details TRKA Application Details Handling References for anti-TRKA Antibody (ABIN969444) back to top
Supplier Images
Immunocytochemistry (ICC) image for anti-TRKA antibody (Neurotrophic Tyrosine Kinase, Receptor, Type 1) (AA 33-423) (ABIN969444) Figure 1: Confocal immunofluorescence analysis of PC-12 cells using TrkA mouse mAb (g...
Western Blotting (WB) image for anti-TRKA antibody (Neurotrophic Tyrosine Kinase, Receptor, Type 1) (AA 33-423) (ABIN969444) Figure 2: Western blot analysis using TrkA mouse mAb against extracellular domain of ...