anti-Human TRKA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended TRKA Antibody (supplied by: Log in to see )

Antigen
Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) Antibodies
  • trk
  • trka
  • TRKA
  • MTC
  • TRK
  • TRK1
  • Trk-A
  • p140-TrkA
  • C80751
  • Tkr
  • TrkA
  • Trk
  • CTRKA
  • trkA
  • CAPM1
  • CFTD
  • NEM1
  • OK/SW-cl.5
  • TM-5
  • TM3
  • TM30
  • TM30nm
  • TM5
  • TPMsk3
  • hscp30
  • neurotrophic tyrosine kinase, receptor, type 1
  • tropomyosin 3
  • ntrk1
  • NTRK1
  • LOC100354292
  • Ntrk1
  • TPM3
Epitope
pTyr817
58
26
23
19
18
18
15
15
14
13
13
12
12
12
11
11
10
10
9
9
8
7
7
6
6
6
5
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
430
246
198
2
2
Host
Rabbit
381
73
5
4
3
Clonality
Polyclonal
Conjugate
This TRKA antibody is un-conjugated
17
15
15
12
10
10
9
9
9
9
8
7
7
7
7
7
6
3
2
2
2
2
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
263
148
93
87
67
58
56
43
19
10
5
5
4
4
3
1
Options
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Catalog No. ABIN703330
$ 317.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.670423 ABIN337137 IHC (p) IP WB Rabbit Log in to see Polyclonal
1 ABIN726110 IF (p) IHC (p) WB Rabbit IgG AA 740-796 Log in to see Polyclonal 1
1 ABIN127050 IHC (p) IP WB Rabbit Log in to see Polyclonal 2
1 ABIN271917 IF IHC (p) Rabbit Log in to see Polyclonal
1 ABIN746603 IF (p) IHC (p) WB Rabbit IgG AA 480-520, pTyr496 Log in to see Polyclonal
1 ABIN3044367 IHC (p) WB Rabbit IgG AA 342-361, Middle Region Log in to see Polyclonal 2
1 ABIN746618 IF (p) IHC (p) WB Rabbit IgG pTyr674, pTyr675 Log in to see Polyclonal
1 ABIN372776 IHC (p) IP WB Rabbit IgG Log in to see Polyclonal
1 ABIN726095 IF (p) IHC (p) WB Rabbit IgG AA 640-676 Log in to see Polyclonal
1 ABIN272088 EIA IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN746612 IHC (p) WB HRP Rabbit IgG AA 480-520, pTyr496 Log in to see Polyclonal
1 ABIN746627 IHC (p) WB HRP Rabbit IgG pTyr674, pTyr675 Log in to see Polyclonal
1 ABIN746605 IHC (p) WB Biotin Rabbit IgG AA 480-520, pTyr496 Log in to see Polyclonal
1 ABIN726119 IHC (p) WB HRP Rabbit IgG AA 740-796 Log in to see Polyclonal
1 ABIN1737561 IHC (p) IP WB Rabbit IgG Log in to see Polyclonal
1 ABIN967209 IHC (p) WB Rabbit IgG Middle Region Log in to see Polyclonal 3
1 ABIN1417066 IHC (p) WB HRP Rabbit IgG pTyr791 Log in to see Polyclonal
1 ABIN746620 IHC (p) WB Biotin Rabbit IgG pTyr674, pTyr675 Log in to see Polyclonal
1 ABIN726104 IHC (p) WB HRP Rabbit IgG AA 640-676 Log in to see Polyclonal
1 ABIN726112 IHC (p) WB Biotin Rabbit IgG AA 740-796 Log in to see Polyclonal

General

Antigen Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) Antibodies
Epitope pTyr817
(58), (26), (23), (19), (18), (18), (15), (15), (14), (13), (13), (12), (12), (12), (11), (11), (10), (10), (9), (9), (8), (7), (7), (6), (6), (6), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(430), (246), (198), (2), (2)
Host Rabbit
(381), (73), (5), (4), (3)
Clonality
Polyclonal
Conjugate This TRKA antibody is un-conjugated
(17), (15), (15), (12), (10), (10), (9), (9), (9), (9), (8), (7), (7), (7), (7), (7), (6), (3), (2), (2), (2), (2), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(263), (148), (93), (87), (67), (58), (56), (43), (19), (10), (5), (5), (4), (4), (3), (1)
Pubmed 1 reference available
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Product Details anti-TRKA Antibody

Target Details TRKA Application Details Handling References for anti-TRKA antibody (ABIN703330) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human TrkA Tyr791+TrkB Tyr817
Isotype IgG

Target Details TRKA

Product Details anti-TRKA Antibody Application Details Handling References for anti-TRKA antibody (ABIN703330) Images back to top
Antigen
Alternative Name TrkA /TrkB (NTRK1 Antibody Abstract)
Background

The Trk family of nerve growth factor receptors includes Trk A(also referfed to as Trk A gp140),Trk B and Trk C. The prototype member of this gene family, Trk A, encodes a 140 kDa cell surface receptor , gp140, the expression of which is restricted in vivo to neurons of the sensory spinal and cranial gangliaof neurocrest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk gp 140 in neural cell lines and in embryonic dorsal root ganglia. By comparison, BDNF and to a lesser extent, NT-3, but not NGF, can induce tyrosine phophorylayion of Trk B gp 145. The third member of the Trk receptor family, Trk C incodes a 140 kDa protein, Trk C gp140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3.An additional component of the Trk receptor complex, NGFR p175, binds to neurotrophic factors with low affinity but is required for efficient signaling. NGFR p175 accelerates Trk activation and may recruit downstream dffector molecules to the ligand-bound receptor complex.

Synonyms: MTC, TRK, TRKA, NTRK1, NTRK2, TRKB

Gene ID 4914
Pathways RTK Signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process

Application Details

Product Details anti-TRKA Antibody Target Details TRKA Handling References for anti-TRKA antibody (ABIN703330) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-TRKA Antibody Target Details TRKA Application Details References for anti-TRKA antibody (ABIN703330) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-TRKA antibody (ABIN703330)

Product Details anti-TRKA Antibody Target Details TRKA Application Details Handling Images back to top
Product cited in:

Ullrich, Weber, Post, Popp, Grein, Zechner, Guerrero González, Kreis, Schmitt, Üçeyler, Lesch, Schuh: "OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency." in: Molecular psychiatry, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Images

Product Details anti-TRKA Antibody Target Details TRKA Application Details Handling References for anti-TRKA antibody (ABIN703330) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (pTyr817) antibody (ABIN703330) Paraformaldehyde-fixed, paraffin embedded rat brain; Antigen retrieval by boiling in ...