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anti-Mouse (Murine) TRKB antibody for Immunoprecipitation

Recommended TRKB Antibody (supplied by: Log in to see )

Antigen
Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Antibodies
  • AI848316
  • C030027L06Rik
  • gp145-trkb
  • GP145-TrkB
  • NTRK2
  • ntrk2
  • RATTRKB1
  • si:ch211-220b11.1
  • Tkrb
  • Trk-B
  • trk-B
  • TRKB
  • trkb
  • trkB
  • TrkB
  • trkb-b
  • TRKB1
  • trkB2
  • xtrkb
Reactivity
Chicken, Human, Mouse (Murine), Rat (Rattus)
266
145
140
8
6
4
4
4
2
Host
Rabbit
227
57
12
5
3
Clonality
Polyclonal
Conjugate
This TRKB antibody is un-conjugated
7
7
7
6
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
223
126
103
40
36
26
23
6
6
2
2
2
1
1
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Catalog No. ABIN223287
$ 336.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.000889573 ABIN1585457 IP IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
0.000889573 ABIN1003382 IF IP WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-TRKB antibody for Immunoprecipitation

Similar anti-TRKB Antibodies

Application / Reactivity Chicken Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 6 Antibodies 196 Antibodies 104 Antibodies 100 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 5 Antibodies 2 Antibodies 3 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 27 Antibodies 21 Antibodies 21 Antibodies
Immunohistochemistry (IHC) 68 Antibodies 77 Antibodies 88 Antibodies 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies

General

Antigen Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Antibodies
Reactivity Chicken, Human, Mouse (Murine), Rat (Rattus)
(266), (145), (140), (8), (6), (4), (4), (4), (2)
Host Rabbit
(227), (57), (12), (5), (3)
Clonality
Polyclonal
Conjugate This TRKB antibody is un-conjugated
(7), (7), (7), (6), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(223), (126), (103), (40), (36), (26), (23), (6), (6), (2), (2), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-TRKB Antibody

Target Details TRKB Application Details Handling References for anti-TRKB Antibody (ABIN223287) Images
Blocking Peptide Blocking peptide for this product available: ABIN412957
Specificity Trk protein exists as variably glycosylated entities with the major forms having molecular weights of 140 kDa, 110 kDa, and the unglycosylated form of 80 kDa. .
Purification Affinity purified
Immunogen Synthetic peptide surrounding amino acid 810 of human TrkB
Isotype IgG

Target Details TRKB

Product Details anti-TRKB Antibody Application Details Handling References for anti-TRKB Antibody (ABIN223287) Images back to top
Antigen
Alternative Name TrkB (NTRK2 Antibody Abstract)
Background Due to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular weights of 140-145 kDa, 110 kDa and the unglycosylated form of 80 kDa. trkB contains 33.3 % carbohydrate by weight representing modification on 10 of 12 N-glycosylation sites. The primary ligand for trkB is BDNF which induces the phosphorylation of the protein and subsequent binding of PLC-gamma via SH2 domains. TrkB may function to modulate neuronal responses to the neurotrophins acting throμgh trkB such as BDNF.
Synonyms: NTRK2 , GP145-TrkB , TRKB , Trk-B , tyrosine receptor kinase
Gene ID 25054
UniProt Q63604
Research Area Cancer
Pathways RTK Signaling, Neurotrophin Signaling Pathway

Application Details

Product Details anti-TRKB Antibody Target Details TRKB Handling References for anti-TRKB Antibody (ABIN223287) Images back to top
Application Notes Western blotting (0.5-4 μg/mL), Immunofluorescence (5-10 μg/mL).
However, the optimal concentrations should be determined individually.
Comment

Country of Animal Origin: China

Restrictions For Research Use only

Handling

Product Details anti-TRKB Antibody Target Details TRKB Application Details References for anti-TRKB Antibody (ABIN223287) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer 100 μg (0.2 mg/mL) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-TRKB Antibody (ABIN223287)

Product Details anti-TRKB Antibody Target Details TRKB Application Details Handling Images back to top
Product cited in:

Shen, Ghai, Sompol, Liu, Cao, Iuvone, Ye: "N-acetyl serotonin derivatives as potent neuroprotectants for retinas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 9, pp. 3540-5, 2012

Jang, Liu, Pradoldej, Tosini, Chang, Iuvone, Ye: "N-acetylserotonin activates TrkB receptor in a circadian rhythm." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 8, pp. 3876-81, 2010

Jang, Liu, Chan, France, Sayeed, Tang, Lin, Xiao, Andero, Chang, Ressler, Ye: "Deoxygedunin, a natural product with potent neurotrophic activity in mice." in: PLoS ONE, Vol. 5, Issue 7, pp. e11528, 2010

Jang, Liu, Yepes, Shepherd, Miller, Liu, Wilson, Xiao, Blanchi, Sun, Ye: "A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 6, pp. 2687-92, 2010

Images

Product Details anti-TRKB Antibody Target Details TRKB Application Details Handling References for anti-TRKB Antibody (ABIN223287) back to top
Supplier Images
Western Blotting (WB) image for anti-TRKB antibody (Neurotrophic Tyrosine Kinase, Receptor, Type 2) (ABIN223287) Western Blot Analysis of trkB expression in HL-60 Cell Lysate.