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anti-Rat (Rattus) TRKB antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended TRKB Antibody (supplied by: Log in to see )

Antigen
Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Antibodies
  • AI848316
  • C030027L06Rik
  • gp145-trkb
  • GP145-TrkB
  • NTRK2
  • ntrk2
  • RATTRKB1
  • si:ch211-220b11.1
  • Tkrb
  • Trk-B
  • trk-B
  • TRKB
  • trkb
  • trkB
  • TrkB
  • trkb-b
  • TRKB1
  • trkB2
  • xtrkb
Epitope
AA 370-429
26
24
20
16
16
15
13
12
12
12
10
7
7
7
6
6
6
5
5
5
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
280
149
144
9
6
4
4
4
2
1
Host
Rabbit
231
67
12
5
3
Clonality
Polyclonal
Conjugate
This TRKB antibody is un-conjugated
7
7
7
6
5
5
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
230
128
110
49
40
30
22
11
7
3
2
2
1
1
Supplier
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Catalog No. ABIN725870
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008846439 ABIN727310 IF (p) IHC (p) WB Rabbit IgG AA 30-80 Log in to see Polyclonal
0.0008846439 ABIN918691 IF (p) Alexa Fluor 647 Rabbit IgG AA 30-80 Log in to see Polyclonal
0.0008846439 ABIN918694 IF (p) Alexa Fluor 647 Rabbit IgG AA 370-429 Log in to see Polyclonal
0.0008846439 ABIN918696 IF (p) Alexa Fluor 488 Rabbit IgG AA 370-429 Log in to see Polyclonal
0.0008846439 ABIN918700 IF (p) Alexa Fluor 350 Rabbit IgG AA 30-80 Log in to see Polyclonal
0.0008846439 ABIN918698 IF (p) Alexa Fluor 350 Rabbit IgG AA 370-429 Log in to see Polyclonal
0.0008846439 ABIN918693 IF (p) Alexa Fluor 555 Rabbit IgG AA 370-429 Log in to see Polyclonal
0.0008846439 ABIN918695 IF (p) Alexa Fluor 488 Rabbit IgG AA 30-80 Log in to see Polyclonal
0.0008846439 ABIN918699 IF (p) Alexa Fluor 555 Rabbit IgG AA 30-80 Log in to see Polyclonal
0.0008846439 ABIN725873 IF (p) Cy3 Rabbit IgG AA 370-429 Log in to see Polyclonal
0.0008846439 ABIN725876 IF (p) Cy7 Rabbit IgG AA 370-429 Log in to see Polyclonal
0.0008846439 ABIN725877 IF (p) FITC Rabbit IgG AA 370-429 Log in to see Polyclonal
0.0008846439 ABIN725874 IF (p) Cy5 Rabbit IgG AA 370-429 Log in to see Polyclonal
0.0008846439 ABIN725875 IF (p) Cy5.5 Rabbit IgG AA 370-429 Log in to see Polyclonal
0.0008846439 ABIN727316 IF (p) Cy7 Rabbit IgG AA 30-80 Log in to see Polyclonal
0.0008846439 ABIN727315 IF (p) Cy5.5 Rabbit IgG AA 30-80 Log in to see Polyclonal
0.0008846439 ABIN727313 IF (p) Cy3 Rabbit IgG AA 30-80 Log in to see Polyclonal
0.0008846439 ABIN727314 IF (p) Cy5 Rabbit IgG AA 30-80 Log in to see Polyclonal
0.0008846439 ABIN727317 IF (p) FITC Rabbit IgG AA 30-80 Log in to see Polyclonal
0.0008846439 ABIN2809018 IF (p) Alexa Fluor 594 Rabbit IgG AA 370-429 Log in to see Polyclonal

Top referenced anti-TRKB antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-TRKB Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
BioImaging (BI) 2 Antibodies
ELISA 33 Antibodies 45 Antibodies
Fluorescence Microscopy (FM) 2 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 7 Antibodies 7 Antibodies
Immunofluorescence (IF) 23 Antibodies 23 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies 23 Antibodies
Immunohistochemistry (IHC) 70 Antibodies 79 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 23 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 102 Antibodies

General

Antigen Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Antibodies
Epitope AA 370-429
(26), (24), (20), (16), (16), (15), (13), (12), (12), (12), (10), (7), (7), (7), (6), (6), (6), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(280), (149), (144), (9), (6), (4), (4), (4), (2), (1)
Host Rabbit
(231), (67), (12), (5), (3)
Clonality
Polyclonal
Conjugate This TRKB antibody is un-conjugated
(7), (7), (7), (6), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(230), (128), (110), (49), (40), (30), (22), (11), (7), (3), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-TRKB Antibody

Target Details TRKB Application Details Handling References for anti-TRKB Antibody (ABIN725870) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from rat TrkB
Isotype IgG

Target Details TRKB

Product Details anti-TRKB Antibody Application Details Handling References for anti-TRKB Antibody (ABIN725870) Images back to top
Antigen
Alternative Name TrkB (NTRK2 Antibody Abstract)
Background

Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades. Through SHC1, FRS2, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth. Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival. Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity. Thereby, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival. Hence, it is able to suppress anoikis, the apoptosis resulting from loss of cell-matrix interactions. May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia.

Subcellular location: Extracellular


Synonyms: TRKB, trk-B, GP145-TrkB, BDNF/NT-3 growth factors receptor, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Tropomyosin-related kinase B, NTRK2
Gene ID 4915
UniProt Q16620
Research Area Cancer
Pathways RTK Signaling, Neurotrophin Signaling Pathway

Application Details

Product Details anti-TRKB Antibody Target Details TRKB Handling References for anti-TRKB Antibody (ABIN725870) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-TRKB Antibody Target Details TRKB Application Details References for anti-TRKB Antibody (ABIN725870) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-TRKB Antibody (ABIN725870)

Product Details anti-TRKB Antibody Target Details TRKB Application Details Handling Images back to top
Product cited in:

Zhu, Xia, Han, Shao, Jing, Fan, Liu, Diao, Lv, Sun: "Xiao Yao San Improves Depressive-Like Behavior in Rats through Modulation of ?-Arrestin 2-Mediated Pathways in Hippocampus." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 902516, 2014

Images

Product Details anti-TRKB Antibody Target Details TRKB Application Details Handling References for anti-TRKB Antibody (ABIN725870) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-TRKB antibody (Neurotrophic Tyrosine Kinase, Receptor, Type 2) (AA 370-429) (ABIN725870) Formalin-fixed and paraffin embedded: human nasopharyngeal carcinoma labeled with Ant...
SDS-PAGE (SDS) image for anti-TRKB antibody (Neurotrophic Tyrosine Kinase, Receptor, Type 2) (AA 370-429) (ABIN725870) L1 rat brain lysates L2 rat kidney lysates probed with Anti Trk B/NTRK2 Polyclonal An...