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Browse our anti-TSC1 (TSC1) Antibodies

Full name:
anti-Tuberous Sclerosis 1 Antibodies (TSC1)
On www.antibodies-online.com are 810 Tuberous Sclerosis 1 (TSC1) Antibodies from 28 different suppliers available. Additionally we are shipping TSC1 Proteins (3) and TSC1 Kits (2) and many more products for this protein. A total of 832 TSC1 products are currently listed.
Synonyms:
hamartin, LAM, mKIAA0243, TSC, tsc1, wu:fc38b04

Most Popular Reactivities for anti-TSC1 (TSC1) Antibodies

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anti-Human TSC1 Antibodies:

anti-Mouse (Murine) TSC1 Antibodies:

anti-Rat (Rattus) TSC1 Antibodies:

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Top referenced anti-TSC1 Antibodies

  1. Human Polyclonal TSC1 Primary Antibody for DB - ABIN1881927 : Hoogeveen-Westerveld, Exalto, Maat-Kievit, van den Ouweland, Halley, Nellist: Analysis of TSC1 truncations defines regions involved in TSC1 stability, aggregation and interaction. in Biochimica et biophysica acta 2010 (PubMed)
    Show all 5 references for ABIN1881927

  2. Human Polyclonal TSC1 Primary Antibody for DB - ABIN1881929 : Mehta, Vazquez, Kulkarni, Kerrigan, Atwal, Metsugi, Toppmeyer, Levine, Hirshfield: Polymorphic variants in TSC1 and TSC2 and their association with breast cancer phenotypes. in Breast cancer research and treatment 2011 (PubMed)
    Show all 5 references for ABIN1881929

  3. Human Polyclonal TSC1 Primary Antibody for EIA - ABIN358402 : Wu, Khalil, Keehn, Saeed, Morgan: Hamartin and tuberin immunohistochemical expression in cutaneous fibroepithelial polyps. in Journal of cutaneous pathology 2004 (PubMed)
    Show all 5 references for ABIN358402

  4. Human Polyclonal TSC1 Primary Antibody for EIA, IF - ABIN501071 : Shamji, Nghiem, Schreiber: Integration of growth factor and nutrient signaling: implications for cancer biology. in Molecular cell 2003 (PubMed)
    Show all 4 references for ABIN501071

  5. Human Polyclonal TSC1 Primary Antibody for IHC, ELISA - ABIN185619 : Chan, Zhang, Roberts, Jozwiak, Wieslawa, Lewin-Kowalik, Kotulska, Kwiatkowski: Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation. in Journal of neuropathology and experimental neurology 2004 (PubMed)
    Show all 3 references for ABIN185619

  6. Human Polyclonal TSC1 Primary Antibody for IF, IHC (p) - ABIN652207 : Lewis, Thomas, Murphy, Sampson: Genotype and psychological phenotype in tuberous sclerosis. in Journal of medical genetics 2004 (PubMed)
    Show all 2 references for ABIN652207

  7. Mouse (Murine) Polyclonal TSC1 Primary Antibody for DB - ABIN1881917 : Akpa, Oyejola: Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review. in Journal of infection in developing countries 2010 (PubMed)
    Show all 2 references for ABIN1881917

  8. Mouse (Murine) Polyclonal TSC1 Primary Antibody for DB - ABIN1881914 : Kladney, Cardiff, Kwiatkowski, Chiang, Weber, Arbeit, Lu: Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice. in Cancer research 2010 (PubMed)
    Show all 2 references for ABIN1881914

  9. Human Monoclonal TSC1 Primary Antibody for FACS, WB - ABIN4899266 : Zhao, Zhao, Poage, Mazumdar, Zhang, Hill, Hartman, Savage, Mills, Brown: Death-associated protein kinase 1 promotes growth of p53-mutant cancers. in The Journal of clinical investigation 2015 (PubMed)

More Antibodies against TSC1 Interaction Partners

Zebrafish Tuberous Sclerosis 1 (TSC1) interaction partners

  1. Tsc1 is involved in regulation of interactive network between the cilium and the TOR pathway.

Human Tuberous Sclerosis 1 (TSC1) interaction partners

  1. The mTOR (show FRAP1 Antibodies)-dependent, epithelial phenotype of TSC (show SLC12A3 Antibodies) astrocytes suggests TSC1/2 and mTOR (show FRAP1 Antibodies) tune the phosphorylation level of catenin delta-1 (show CTNND1 Antibodies) by controlling PKCe (show PRKCE Antibodies) activity, thereby regulating the mesenchymal-epithelial-transition (MET)

  2. We conditionally ablated the tuberous sclerosis complex 1 (Tsc1) gene, an mTOR (show FRAP1 Antibodies) inhibitor, in the rods of the Pde6b (show PDE6B Antibodies)(H620Q/H620Q) preclinical RP mouse model and observed, functionally and morphologically, an improvement in the survival of rods and cones at early and late disease stages.

  3. TSC1 mutations leading to tuberous sclerosis in Chinese children.

  4. Our results indicate that TSC2 (show TSC2 Antibodies) and less commonly TSC1 alterations are the primary essential driver event in angiomyolipoma/Lymphangioleiomyomatosis, whereas other somatic mutations are rare and likely do not contribute to tumor development.

  5. brain somatic mutations in TSC1 and TSC2 (show TSC2 Antibodies) cause focal cortical dysplasia

  6. TSC1 expression is reduced in two subsets of clear-cell renal cell carcinomas, those with monoallelic VHL (show VHL Antibodies) gene inactivation and those with concurrent low HIF-1alpha (show HIF1A Antibodies) and high HIF-2alpha (show EPAS1 Antibodies) expression.

  7. Repression of TSC1/TSC2 (show TSC2 Antibodies) mediated by MeCP2 (show MECP2 Antibodies) regulates human embryo lung fibroblast cell differentiation and proliferation.

  8. TSC1 mutation is associated in patients, diagnosed with tuberous sclerosis associated vascular malformation.

  9. Novel TSC1 mutations in Chinese patients with tuberous sclerosis.

  10. Gene expression level of TSC1 is significantly higher in AD patients when compared to normal controls.

Mouse (Murine) Tuberous Sclerosis 1 (TSC1) interaction partners

  1. Tsc1 haploinsufficiency is sufficient to increase dendritic patterning and Filamin A (show FLNA Antibodies) levels. Reducing filamin A (FLNA (show FLNA Antibodies)) levels has been shown to decrease Tsc1(+/-) dendritic complexity, these data suggest that increased FLNA (show FLNA Antibodies) levels in Tsc1(+/-) mice contribute to abnormal dendritic patterning in the Tsc1 heterozygote condition of individuals with tuberous sclerosis complex.

  2. selective mTORC1 activation in smooth muscle cells induced by deleting the negative mTORC1 regulator tuberous sclerosis complex 1 gene (TSC1) was sufficient to produce pulmonary hypertension.

  3. The present study demonstrates for the first time evidence of microglial activation in a mouse model of TSC (show SLC12A3 Antibodies) with mutation tsc1.

  4. Repression of TSC1/TSC2 (show TSC2 Antibodies) mediated by MeCP2 (show MECP2 Antibodies) regulates human embryo lung fibroblast cell differentiation and proliferation.

  5. suppression of AKT (show AKT1 Antibodies) by hyperactivation of mTORC1, inhibition on nuclear ERalpha (show ESR1 Antibodies) signaling, and down-regulation of cell-cycle-driving proteins play important roles in the retarded mammary development induced by Tsc1 deletion.

  6. TSC1 knockout mice are lean, glucose intolerant with a decreased activation of protein kinase B (Akt/PKB (show AKT1 Antibodies)) targets that regulate glucose transporters in skeletal muscle.

  7. a pivotal role for Tsc1 in regulating various aspects of visual-pathway development, is reported.

  8. PAK2 (show PAK2 Antibodies) is a direct effector of TSC1-TSC2 (show TSC2 Antibodies)-RHEB (show RHEB Antibodies) signaling and a new target for rational drug therapy in TSC (show SLC12A3 Antibodies).

  9. Tsc1 plays a critical role in regulating macrophage survival, function and polarization via inhibition of mTORC1 activity.

  10. TSC1-KO results in the accumulation of transitional-1 B cells and progressive losses of B cells as they mature beyond the T1 stage. However, Peyer's patch germinal centers are unimpaired in TSC1-KO mice.

TSC1 Antigen Profile

Antigen Summary

This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with TSC1

  • tuberous sclerosis 1 (TSC1) antibody
  • tuberous sclerosis 1b (tsc1b) antibody
  • tuberous sclerosis 1 (tsc1) antibody
  • tuberous sclerosis 1 (Tsc1) antibody
  • hamartin antibody
  • LAM antibody
  • mKIAA0243 antibody
  • TSC antibody
  • tsc1 antibody
  • wu:fc38b04 antibody

Protein level used designations for TSC1

tuberous sclerosis 1 protein , tuberous sclerosis 1 , fc38b04 , hamartin , hamartin-like , tumor suppressor , tuberous sclerosis 1 protein homolog , chromosome 9 TSC1

GENE ID SPECIES
100066615 Equus caballus
464818 Pan troglodytes
100017591 Monodelphis domestica
100080641 Ornithorhynchus anatinus
100330617 Danio rerio
100338695 Oryctolagus cuniculus
100380126 Xenopus (Silurana) tropicalis
100407741 Callithrix jacchus
100471530 Ailuropoda melanoleuca
100539473 Meleagris gallopavo
100587112 Nomascus leucogenys
7248 Homo sapiens
64930 Mus musculus
60445 Rattus norvegicus
480688 Canis lupus familiaris
100154726 Sus scrofa
533440 Bos taurus
417166 Gallus gallus
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