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|Application / Reactivity||Human|
|Dot Blot (DB)||209 Antibodies|
|Enzyme Immunoassay (EIA)||4 Antibodies|
|Flow Cytometry (FACS)||4 Antibodies|
|Immunochromatography (IC)||2 Antibodies|
|Immunocytochemistry (ICC)||14 Antibodies|
|Immunofluorescence (IF)||18 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||34 Antibodies|
|Immunohistochemistry (IHC)||64 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||34 Antibodies|
|Immunoprecipitation (IP)||8 Antibodies|
|Western Blotting (WB)||139 Antibodies|
|Antigen||Tuberous Sclerosis 1 (TSC1) Antibodies|
|Conjugate||This TSC1 antibody is un-conjugated Alternatives|
Dot Blot (DB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-TSC1 AntibodyTarget Details TSC1 Application Details Handling References for anti-TSC1 Antibody (ABIN1881927) Images
|Predicted Reactivity||Rat (Rattus)|
|Purification||This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Immunogen||This TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S682 of human TSC1.|
Target Details TSC1Product Details anti-TSC1 Antibody Application Details Handling References for anti-TSC1 Antibody (ABIN1881927) Images back to top
|Alternative Name||TSC1 (TSC1 Antibody Abstract)|
This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.
Synonyms: TSC1, KIAA0243, TSC, Hamartin, Tuberous sclerosis 1 protein
|NCBI Accession||NP_001155899, NP_001155898, NP_000359|
|Pathways||RTK Signaling, AMPK Signaling|
Application DetailsProduct Details anti-TSC1 Antibody Target Details TSC1 Handling References for anti-TSC1 Antibody (ABIN1881927) Images back to top
|Application Notes||DB: 1:500|
|Restrictions||For Research Use only|
HandlingProduct Details anti-TSC1 Antibody Target Details TSC1 Application Details References for anti-TSC1 Antibody (ABIN1881927) Images back to top
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.|
|Precaution of Use||WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.|
References for anti-TSC1 Antibody (ABIN1881927)Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Handling Images back to top
|Product cited in:||
Mehta, Vazquez, Kulkarni et al.: "Polymorphic variants in TSC1 and TSC2 and their association with breast cancer phenotypes." in: Breast cancer research and treatment, Vol. 125, Issue 3, pp. 861-8, 2011 (PubMed).
Mieulet, Lamb: "Tuberous sclerosis complex: linking cancer to metabolism." in: Trends in molecular medicine, Vol. 16, Issue 7, pp. 329-35, 2010 (PubMed).
Hoogeveen-Westerveld, Exalto, Maat-Kievit et al.: "Analysis of TSC1 truncations defines regions involved in TSC1 stability, aggregation and interaction." in: Biochimica et biophysica acta, Vol. 1802, Issue 9, pp. 774-81, 2010 (PubMed).
Liu, Wu, Chen et al.: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, 2010 (PubMed).
Guo, Ying, Zhang et al.: "Tandem affinity purification and identification of the human TSC1 protein complex." in: Acta biochimica et biophysica Sinica, Vol. 42, Issue 4, pp. 266-73, 2010 (PubMed).
ImagesProduct Details anti-TSC1 Antibody Target Details TSC1 Application Details Handling References for anti-TSC1 Antibody (ABIN1881927) back to top