You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-TSC2 (TSC2) Antibodies

Full name:
anti-Tuberous Sclerosis 2 Antibodies (TSC2)
On www.antibodies-online.com are 722 Tuberous Sclerosis 2 (TSC2) Antibodies from 24 different suppliers available. Additionally we are shipping TSC2 Kits (7) and and many more products for this protein. A total of 752 TSC2 products are currently listed.
Synonyms:
fc16b02, LAM, Nafld, Rc, Tcs2, TSC2, TSC4, tuberin, wu:fc16b02
list all antibodies Gene Name GeneID UniProt
TSC2 7249 P49815
TSC2 22084  
TSC2 24855 P49816

Show all species

Show all synonyms

All available anti-TSC2 Antibodies

Go to our pre-filtered search.

Top referenced anti-TSC2 Antibodies

  1. Human Polyclonal TSC2 Primary Antibody for DB, IF - ABIN1881949 : Li, Inoki, Guan: Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity. in Molecular and cellular biology 2004 (PubMed)
    Show all 6 references for ABIN1881949

  2. Human Polyclonal TSC2 Primary Antibody for DB, EIA - ABIN358369 : Karbowniczek, Cash, Cheung, Robertson, Astrinidis, Henske: Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358369

  3. Human Polyclonal TSC2 Primary Antibody for EIA - ABIN358411 : Corradetti, Inoki, Bardeesy, DePinho, Guan: Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome. in Genes & development 2004 (PubMed)
    Show all 5 references for ABIN358411

  4. Human Polyclonal TSC2 Primary Antibody for EIA - ABIN358353 : Birchenall-Roberts, Fu, Bang, Dambach, Resau, Sadowski, Bertolette, Lee, Kim, Ruscetti: Tuberous sclerosis complex 2 gene product interacts with human SMAD proteins. A molecular link of two tumor suppressor pathways. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358353

  5. Human Polyclonal TSC2 Primary Antibody for DB, EIA - ABIN358410 : Lewis, Thomas, Murphy, Sampson: Genotype and psychological phenotype in tuberous sclerosis. in Journal of medical genetics 2004 (PubMed)
    Show all 5 references for ABIN358410

  6. Human Polyclonal TSC2 Primary Antibody for EIA, IF - ABIN501075 : Shamji, Nghiem, Schreiber: Integration of growth factor and nutrient signaling: implications for cancer biology. in Molecular cell 2003 (PubMed)
    Show all 4 references for ABIN501075

  7. Human Polyclonal TSC2 Primary Antibody for EIA, WB - ABIN501073 : Inoki, Ouyang, Li, Guan: Signaling by target of rapamycin proteins in cell growth control. in Microbiology and molecular biology reviews : MMBR 2005 (PubMed)
    Show all 4 references for ABIN501073

  8. Human Polyclonal TSC2 Primary Antibody for ELISA, WB - ABIN1533200 : : Identification and characterization of the tuberous sclerosis gene on chromosome 16. in Cell 1994 (PubMed)
    Show all 3 references for ABIN1533200

  9. Human Polyclonal TSC2 Primary Antibody for IHC, ELISA - ABIN1532185 : Xu, Sterner, Maheshwar, Wilson, Nellist, Short, Haines, Sampson, Ramesh: Alternative splicing of the tuberous sclerosis 2 (TSC2) gene in human and mouse tissues. in Genomics 1995 (PubMed)
    Show all 2 references for ABIN1532185

More Antibodies against TSC2 Interaction Partners

Zebrafish Tuberous Sclerosis 2 (TSC2) interaction partners

  1. This is the first report using an animal model to show interactions between tsc2, mTORC1 and p53 (show TP53 Antibodies) during tumorigenesis.

  2. These results demonstrate a highly conserved role of tsc2 in zebrafish and establish a new animal model for studies of Tuberous sclerosis complex.

Human Tuberous Sclerosis 2 (TSC2) interaction partners

  1. By interfering with TSC (show SLC12A3 Antibodies)-Rheb (show RHEB Antibodies) complex, arginine relieves allosteric inhibition of Rheb (show RHEB Antibodies) by TSC (show SLC12A3 Antibodies). Arginine cooperates with growth factor signaling which further promotes dissociation of TSC2 from lysosomes and activation of mTORC1.

  2. IQ/DQ correlates inversely with predicted levels and/or deleterious biochemical effects of mutant TSC1 (show TSC1 Antibodies) or TSC2 protein in tuberous sclerosis complex.

  3. Results confirm strong association between TSC2 mutation and angiomyolipoma burden, and they indicate that everolimus response occurs regardless of mutation type or location or when no mutation in TSC1 (show TSC1 Antibodies) or TSC2 has been identified.

  4. AKT3 (show AKT3 Antibodies) has a role in prostate cancer proliferation through regulation of Akt (show AKT1 Antibodies), B-Raf (show SNRPE Antibodies), and TSC1 (show TSC1 Antibodies)/TSC2

  5. PAK2 (show PAK2 Antibodies) is a direct effector of TSC1 (show TSC1 Antibodies)-TSC2-RHEB (show RHEB Antibodies) signaling and a new target for rational drug therapy in TSC (show SLC12A3 Antibodies).

  6. Data show that 10 pathogenic mutations were quickly identified, 7 were located in tuberous sclerosis 1 protein (TSC1 (show TSC1 Antibodies)) and 3 were observed in tuberous sclerosis 2 protein (TSC2).

  7. Tuberous sclerosis is a syndrome caused by dominant mutations in Tuberin (TSC2),causing Autism spectrum disorder - like behaviors, seizures, intellectual disability and characteristic brain and skin lesions.

  8. TSC1 (show TSC1 Antibodies) and TSC2 mutations are associated with tuberous sclerosis.

  9. Lysosomal recruitment of TSC2 is a universal response to stimuli that inactivate mTORC1, and that the presence of any single stress is sufficient to cause TSC2 lysosomal localization.

  10. TSC (show SLC12A3 Antibodies)-related tumors can increase the mutation detection rate, indicate that it is not likely that a third TSC (show SLC12A3 Antibodies) gene exists, and enable provision of genetic counseling to the substantial population of TSC (show SLC12A3 Antibodies) individuals who are currently NMI (show MYO1C Antibodies)

Mouse (Murine) Tuberous Sclerosis 2 (TSC2) interaction partners

  1. autophagy via the TSC2-mTORC1 signaling pathway plays an important role in maintenance of cardiac function and mitochondrial quantity and size in the heart.

  2. PAK2 (show PAK2 Antibodies) is a direct effector of TSC1 (show TSC1 Antibodies)-TSC2-RHEB (show RHEB Antibodies) signaling and a new target for rational drug therapy in TSC (show SLC12A3 Antibodies).

  3. Data indicate that an AMP (show TMPRSS5 Antibodies)-ctivated kinase (AMPK (show PRKAA1 Antibodies))/cell-cycle inhibitor (show CDKN2A Antibodies) p27KIP1 (p27 (show CDKN1B Antibodies)) axis drives activation of autophagy in rapamycin-treated tuberous sclerosis 2 protein (Tsc2)-null cells.

  4. Lysosomal recruitment of TSC2 is a universal response to stimuli that inactivate mTORC1, and that the presence of any single stress is sufficient to cause TSC2 lysosomal localization.

  5. Axitinib is an effective inhibitor of Tsc2-null lesion growth.

  6. Distinct germline progenitor subsets are defined through Tsc2-mTORC1 signaling.

  7. PLK1 (show PLK1 Antibodies) protein levels are increased in hamartin (show TSC1 Antibodies) and tuberin deficient cells and Lymphangioleiomyomatosis patient-derived specimens, and that this increase is rapamycin-sensitive.

  8. these results demonstrate that TSC2-deficient cells have enhanced choline phospholipid metabolism and reveal a novel function of the TSC (show SLC12A3 Antibodies) proteins in choline lysoglycerophospholipid metabolism

  9. TSC2/mTORC1 signaling contributes to the maintenance of intestinal epithelium homeostasis by regulating Notch (show NOTCH1 Antibodies) activity.

  10. This mode of regulation involves TSC (show SLC12A3 Antibodies) as knockout of TSC1 (show TSC1 Antibodies) or TSC2 rescued TOP mRNAs translation in amino acid-starved cells

Pig (Porcine) Tuberous Sclerosis 2 (TSC2) interaction partners

  1. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK (show PRKAA1 Antibodies)/ERK (show MAPK1 Antibodies)/TSC2/mTOR (show FRAP1 Antibodies) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

Cow (Bovine) Tuberous Sclerosis 2 (TSC2) interaction partners

  1. prostaglandin F2alpha phosphorylates TSC2 and activates mTOR (show FRAP1 Antibodies) and ribosomal protein S6 (show RPS6 Antibodies) kinase (show RPS6KB1 Antibodies) signaling in an AKT (show AKT1 Antibodies)-independent manner

TSC2 Antigen Profile

Antigen Summary

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with TSC2

  • tuberous sclerosis 2 (TSC2) antibody
  • tuberous sclerosis complex 2 (TSC2) (AaeL_AAEL007712) antibody
  • tuberous sclerosis 2 (tsc2) antibody
  • tuberous sclerosis 2 (PGTG_00159) antibody
  • tuberous sclerosis 2 (Tsc2) antibody
  • fc16b02 antibody
  • LAM antibody
  • Nafld antibody
  • Rc antibody
  • Tcs2 antibody
  • TSC2 antibody
  • TSC4 antibody
  • tuberin antibody
  • wu:fc16b02 antibody

Protein level used designations for TSC2

tuberous sclerosis complex 2 (TSC2) , tuberous sclerosis 2 , tuberin-like , tuberin , tuberous sclerosis 2 protein , tuberous sclerosis 2 protein homolog , renal carcinoma , tuberous sclerosis 2 homolog protein

GENE ID SPECIES
100065679 Equus caballus
5569538 Aedes aegypti
468086 Pan troglodytes
567524 Danio rerio
694965 Macaca mulatta
10528144 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100170546 Xenopus (Silurana) tropicalis
100390664 Callithrix jacchus
7249 Homo sapiens
22084 Mus musculus
24855 Rattus norvegicus
479883 Canis lupus familiaris
100505408 Sus scrofa
504985 Bos taurus
416552 Gallus gallus
Selected quality suppliers for anti-TSC2 (TSC2) Antibodies
Did you look for something else?