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anti-Human TSC2 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended TSC2 Antibody (supplied by: Log in to see )

Antigen
Tuberous Sclerosis 2 (TSC2) Antibodies
  • fc16b02
  • LAM
  • Nafld
  • Rc
  • Tcs2
  • TSC2
  • TSC4
  • tuberin
  • wu:fc16b02
Epitope
AA 1600-1650
41
40
34
28
27
27
24
23
22
22
20
20
20
20
20
20
20
20
20
19
18
17
16
15
15
15
13
13
13
12
11
8
8
6
6
6
6
6
6
6
6
6
6
5
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
523
377
208
6
Host
Rabbit
697
24
Clonality
Polyclonal
Conjugate
This TSC2 antibody is un-conjugated
51
51
51
43
42
42
10
10
9
9
9
9
9
9
9
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
387
291
219
148
100
74
63
24
7
7
4
2
1
Supplier
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Catalog No. ABIN701200
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008846439 ABIN712121 IF (p) IHC (p) WB Rabbit IgG pSer1798 Log in to see Polyclonal
0.0008846439 ABIN918956 IF (p) Alexa Fluor 488 Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0008846439 ABIN918955 IF (p) Alexa Fluor 350 Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0008846439 ABIN918957 IF (p) Alexa Fluor 647 Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0008846439 ABIN918954 IF (p) Alexa Fluor 555 Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0008846439 ABIN701205 IF (p) Cy5.5 Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0008846439 ABIN701203 IF (p) Cy3 Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0008846439 ABIN701204 IF (p) Cy5 Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0008846439 ABIN701206 IF (p) Cy7 Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0008846439 ABIN701207 IF (p) FITC Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0008846439 ABIN2807295 IF (p) Alexa Fluor 594 Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0008846439 ABIN746381 IF (p) Cy3 Rabbit IgG pSer1387 Log in to see Polyclonal
0.0008846439 ABIN746382 IF (p) Cy5 Rabbit IgG pSer1387 Log in to see Polyclonal
0.0008846439 ABIN746385 IF (p) FITC Rabbit IgG pSer1387 Log in to see Polyclonal
0.0008846439 ABIN746443 IF (p) Cy5.5 Rabbit IgG pThr927 Log in to see Polyclonal
0.0008846439 ABIN746442 IF (p) Cy5 Rabbit IgG pThr927 Log in to see Polyclonal
0.0008846439 ABIN746444 IF (p) Cy7 Rabbit IgG pThr927 Log in to see Polyclonal
0.0008846439 ABIN746445 IF (p) FITC Rabbit IgG pThr927 Log in to see Polyclonal
0.0008846439 ABIN746651 IF (p) Cy3 Rabbit IgG pSer1254 Log in to see Polyclonal
0.0008846439 ABIN746652 IF (p) Cy5 Rabbit IgG pSer1254 Log in to see Polyclonal

Similar anti-TSC2 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 206 Antibodies 101 Antibodies 72 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 80 Antibodies 48 Antibodies 42 Antibodies
Immunohistochemistry (IHC) 153 Antibodies 49 Antibodies 50 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies 2 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 101 Antibodies 101 Antibodies 101 Antibodies
Immunofluorescence (IF) 61 Antibodies

General

Antigen Tuberous Sclerosis 2 (TSC2) Antibodies
Epitope AA 1600-1650
(41), (40), (34), (28), (27), (27), (24), (23), (22), (22), (20), (20), (20), (20), (20), (20), (20), (20), (20), (19), (18), (17), (16), (15), (15), (15), (13), (13), (13), (12), (11), (8), (8), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(523), (377), (208), (6)
Host Rabbit
(697), (24)
Clonality
Polyclonal
Conjugate This TSC2 antibody is un-conjugated
(51), (51), (51), (43), (42), (42), (10), (10), (9), (9), (9), (9), (9), (9), (9), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(387), (291), (219), (148), (100), (74), (63), (24), (7), (7), (4), (2), (1)
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Product Details anti-TSC2 Antibody

Target Details TSC2 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Tuberin
Isotype IgG

Target Details TSC2

Product Details anti-TSC2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Tuberin (TSC2 Antibody Abstract)
Background

In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. Stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro. Mutations in TSC2 lead to constitutive activation of RAP1A in tumors.

Subcellular location: Cytoplasm


Synonyms: LAM, TSC4, PPP1R160, Tuberin, Tuberous sclerosis 2 protein, TSC2
Gene ID 7249
UniProt P49815
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Pathways RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-TSC2 Antibody Target Details TSC2 Handling Images back to top
Application Notes IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-TSC2 Antibody Target Details TSC2 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-TSC2 Antibody Target Details TSC2 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-TSC2 antibody (Tuberous Sclerosis 2) (AA 1600-1650) (ABIN701200) Formalin-fixed and paraffin embedded human endometrial tissue labeled with Anti-Tuber...
Immunohistochemistry (IHC) image for anti-TSC2 antibody (Tuberous Sclerosis 2) (AA 1600-1650) (ABIN701200) Formalin-fixed and paraffin embedded human gastric adenocarcinoma tissue labeled with...
Immunohistochemistry (IHC) image for anti-TSC2 antibody (Tuberous Sclerosis 2) (AA 1600-1650) (ABIN701200) Formalin-fixed and paraffin embedded rat brain tissue labeled withAnti-Tuberin/TSC2 P...