anti-Mouse (Murine) TSC2 antibody for Dot Blot

Recommended TSC2 Antibody (supplied by: Log in to see )

Antigen
Tuberous Sclerosis 2 (TSC2) Antibodies
  • TSC2
  • fc16b02
  • tuberin
  • wu:fc16b02
  • LAM
  • TSC4
  • Nafld
  • Tcs2
  • Rc
  • tuberous sclerosis 2
  • tuberous sclerosis complex 2 (TSC2)
  • TSC2
  • AaeL_AAEL007712
  • tsc2
  • PGTG_00159
  • Tsc2
Epitope
pSer1343
57
41
40
36
33
30
29
25
21
21
20
20
20
20
20
20
20
20
20
19
18
15
15
15
15
15
13
8
8
8
7
7
6
5
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
559
412
243
13
9
4
4
3
1
1
1
1
Host
Rabbit
727
26
Clonality
Polyclonal
Conjugate
This TSC2 antibody is un-conjugated
51
51
51
43
42
42
10
10
9
9
9
9
9
9
9
9
9
1
1
1
1
1
1
1
1
1
Application
Dot Blot (DB), ELISA
395
286
231
143
119
95
68
24
7
7
5
4
2
1
Supplier
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Catalog No. ABIN3029319
$ 411.13
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
28.924122 ABIN3029320 DB ELISA Rabbit Ig Fraction pSer1348 Log in to see Polyclonal
28.924122 ABIN3029325 DB ELISA Rabbit Ig Fraction pSer1419 Log in to see Polyclonal
28.924122 ABIN3029321 DB ELISA Rabbit Ig Fraction pSer1365 Log in to see Polyclonal
28.924122 ABIN3029327 DB ELISA Rabbit Ig Fraction pSer1421 Log in to see Polyclonal
28.924122 ABIN1881940 DB Rabbit pSer1365 Log in to see Polyclonal
28.924122 ABIN1881942 DB Rabbit pSer1419 Log in to see Polyclonal
28.924122 ABIN1881938 DB Rabbit pSer1343 Log in to see Polyclonal
28.924122 ABIN1881939 DB Rabbit pSer1348 Log in to see Polyclonal
28.924122 ABIN1881943 DB Rabbit pSer1421 Log in to see Polyclonal
28.924122 ABIN1881936 DB Rabbit pSer1096 Log in to see Polyclonal
28.924122 ABIN3029316 DB ELISA Rabbit Ig Fraction pSer1096 Log in to see Polyclonal
28.924122 ABIN3029318 DB ELISA Rabbit Ig Fraction pSer1155 Log in to see Polyclonal
28.924122 ABIN3029324 DB ELISA Rabbit Ig Fraction pSer1412 Log in to see Polyclonal
28.924122 ABIN1881941 DB Rabbit pSer1412 Log in to see Polyclonal
28.924122 ABIN1881937 DB Rabbit pSer1155 Log in to see Polyclonal
1 ABIN1945733 DB ELISA HRP Rabbit IgG pSer1096 Log in to see Polyclonal
1 ABIN1945739 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG pSer1096 Log in to see Polyclonal
1 ABIN1945741 DB ELISA Biotin Rabbit IgG pSer1096 Log in to see Polyclonal
1 ABIN1945740 DB ELISA APC Rabbit IgG pSer1096 Log in to see Polyclonal
1 ABIN1945742 DB ELISA FITC Rabbit IgG pSer1096 Log in to see Polyclonal

General

Antigen Tuberous Sclerosis 2 (TSC2) Antibodies
Epitope pSer1343
(57), (41), (40), (36), (33), (30), (29), (25), (21), (21), (20), (20), (20), (20), (20), (20), (20), (20), (20), (19), (18), (15), (15), (15), (15), (15), (13), (8), (8), (8), (7), (7), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(559), (412), (243), (13), (9), (4), (4), (3), (1), (1), (1), (1)
Host Rabbit
(727), (26)
Clonality
Polyclonal
Conjugate This TSC2 antibody is un-conjugated
(51), (51), (51), (43), (42), (42), (10), (10), (9), (9), (9), (9), (9), (9), (9), (9), (9), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Dot Blot (DB), ELISA
(395), (286), (231), (143), (119), (95), (68), (24), (7), (7), (5), (4), (2), (1)
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Product Details anti-TSC2 Antibody

Target Details TSC2 Application Details Handling Images
Cross-Reactivity (Details) Expected species reactivity: Rat
Purification Antigen affinity purified
Immunogen This phospho-TSC2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1343 of mouse TSC2.
Isotype Ig Fraction

Target Details TSC2

Product Details anti-TSC2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TSC2 (TSC2 Antibody Abstract)
Background In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity). Specifically stimulates the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth (By similarity).
UniProt Q61037
Pathways RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus

Application Details

Product Details anti-TSC2 Antibody Target Details TSC2 Handling Images back to top
Application Notes Titration of the phospho-TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
Restrictions For Research Use only

Handling

Product Details anti-TSC2 Antibody Target Details TSC2 Application Details Images back to top
Format Liquid
Buffer In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot the phospho-TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

Product Details anti-TSC2 Antibody Target Details TSC2 Application Details Handling back to top
Supplier Images
Dot Blot (DB) image for anti-Tuberous Sclerosis 2 (TSC2) (pSer1343) antibody (ABIN3029319) Dot blot analysis of phospho-TSC2 antibody. 50ng of phos-peptide or nonphos-peptide p...