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Browse our TUB Proteins (TUB)

Full name:
Tubby Homolog (Mouse) Proteins (TUB)
On www.antibodies-online.com are 5 Tubby Homolog (Mouse) (TUB) Proteins from 4 different suppliers available. Additionally we are shipping TUB Antibodies (8) and many more products for this protein. A total of 13 TUB products are currently listed.
Synonyms:
MGC78808, MGC79522, MGC80126, MGC84061, rd5, tub, tubby
list all proteins Gene Name GeneID UniProt
TUB 7275 P50607
TUB 22141 P50586
TUB 25609 O88808

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TUB Proteins (TUB) by Origin

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More Proteins for TUB Interaction Partners

Human Tubby Homolog (Mouse) (TUB) interaction partners

  1. Tubby and Tulp1 mediated phagocytosis through MerTK-dependent signaling with non-muscle myosin II redistribution leading to colocalization of phagocytosed vesicles with rearranged NMMIIA.

  2. Tubby and Tulp1 (show TULP1 Proteins) are bridging molecules with their N-terminal region as MERTK (show MERTK Proteins)-binding domain and C-terminal region as phagocytosis prey-binding domain.

  3. Tubby and Tulp1 (show TULP1 Proteins) function as phagocytosis sigmals (eat-me) for retinal pigment epithelium cells and other phagocytes.

  4. TUB could be an important factor in controlling the central regulation of body weight in humans.

  5. TUB is a candidate gene for late-onset obesity in humans

  6. Genetic variation of the TUB gene was associated with both body composition and macronutrient intake, suggesting that TUB might influence eating behavior

  7. Mouse Tubby protein may function as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, providing a direct link between G-protein signaling and the regulation of gene expression.

Mouse (Murine) Tubby Homolog (Mouse) (TUB) interaction partners

  1. Tub has a key role in insulin (show INS Proteins) and leptin (show LEP Proteins) signaling and action in vivo in hypothalamic nuclei.

  2. These results suggest that tubby is a ligand to facilitate microglial phagocytosis through MerTK (show MERTK Proteins) for the maintenance of CNS homeostasis.

  3. Mtap1a (show MAP1A Proteins), which modifies hearing loss in Tub(tub/tub) mice, also modifies retinal degeneration in Tub and Tulp1 (show TULP1 Proteins) mice; functionally nonredundant members of the TULP family (TUB and TULP1 (show TULP1 Proteins)) share a common functional interaction with MTAP1A (show MAP1A Proteins)

  4. Tubby and Tulp1 (show TULP1 Proteins) function as phagocytosis sigmals (eat-me) for retinal pigment epithelium cells and other phagocytes.

  5. TUB plays a role in insulin (show INS Proteins) signalling and fuel homeostasis in adipocytes.

  6. Data show that agouti-related protein (show AGRP Proteins) mRNA levels are significantly lower in obese tub/tub mice as compared to tub/+ mice.

  7. Tubby secretion is partially dependent on its PI(4,5)P(2)-binding activity with an essential secretory signal in the N-terminus.

TUB Protein Profile

Protein Summary

This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with TUB

  • tubby homolog (mouse) (TUB)
  • tubby homolog (tub)
  • tubby homolog (mouse) (tub)
  • tubby protein homolog (LOC100563100)
  • tubby protein homolog (LOC100566184)
  • tubby bipartite transcription factor (TUB)
  • tubby candidate gene (Tub)
  • tubby homolog (mouse) (Tub)
  • MGC78808 protein
  • MGC79522 protein
  • MGC80126 protein
  • MGC84061 protein
  • rd5 protein
  • tub protein
  • tubby protein

Protein level used designations for Tubby Homolog (Mouse) Proteins (TUB)

tubby homolog (mouse) , tubby (mouse homolog) , tubby homolog , tubby protein homolog , tubby homologue , retinal degeneration 5 , tubby protein

GENE ID SPECIES
280949 Bos taurus
423061 Gallus gallus
444597 Xenopus laevis
466436 Pan troglodytes
485377 Canis lupus familiaris
493219 Xenopus (Silurana) tropicalis
539051 Bos taurus
706054 Macaca mulatta
100070898 Equus caballus
100342264 Oryctolagus cuniculus
446449 Xenopus laevis
100456166 Pongo abelii
100520318 Sus scrofa
100546143 Meleagris gallopavo
100563100 Anolis carolinensis
100566184 Anolis carolinensis
100582760 Nomascus leucogenys
7275 Homo sapiens
22141 Mus musculus
25609 Rattus norvegicus
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