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anti-Mouse (Murine) TYRO3 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended TYRO3 Antibody (supplied by: Log in to see )

Antigen
TYRO3 Protein Tyrosine Kinase (TYRO3) Antibodies
  • AI323366
  • brt
  • Brt
  • BYK
  • byk
  • DKFZp469I0432
  • Dtk
  • dtk
  • Etk-2
  • ksy
  • LOC100231598
  • MGC145734
  • REK
  • Rse
  • RSE
  • rse
  • Sky
  • sky
  • tif
  • Tif
  • TYRO3
  • xksy
  • Xksy
Reactivity
Human, Mouse (Murine), Rat (Rattus)
142
32
20
4
1
Host
Rabbit
88
53
1
Clonality
Polyclonal
Conjugate
This TYRO3 antibody is un-conjugated
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
103
62
37
34
18
15
10
10
6
6
6
2
1
Supplier
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Catalog No. ABIN872341
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089791435 ABIN359940 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 5
0.00089791435 ABIN392054 IHC (p) WB Rabbit Ig AA 842-873, C-Term Log in to see Polyclonal
0.00089791435 ABIN906157 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.00089791435 ABIN906162 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal

Top referenced anti-TYRO3 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-TYRO3 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 6 Antibodies 7 Antibodies 61 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 3 Antibodies 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 3 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies 5 Antibodies
Western Blotting (WB) 11 Antibodies 23 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 2 Antibodies
ELISA (Capture) 1 Antibodies
Flow Cytometry (FACS) 6 Antibodies

General

Antigen TYRO3 Protein Tyrosine Kinase (TYRO3) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(142), (32), (20), (4), (1)
Host Rabbit
(88), (53), (1)
Clonality
Polyclonal
Conjugate This TYRO3 antibody is un-conjugated
(4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(103), (62), (37), (34), (18), (15), (10), (10), (6), (6), (6), (2), (1)
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Product Details anti-TYRO3 Antibody

Target Details TYRO3 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Tyrosine-protein kinase receptor TYRO3
Isotype IgG

Target Details TYRO3

Product Details anti-TYRO3 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Tyro3 (TYRO3 Antibody Abstract)
Background

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation and cytoskeleton reorganization. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

Subcellular location: Extracellular


Synonyms: BYK, Dtk, RSE, Rek, Sky, Tif, Etk-2, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase BYK, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase TIF, TYRO3
Gene ID 7301
UniProt Q06418
Research Area Signaling, Tyrosine Kinases
Pathways RTK Signaling

Application Details

Product Details anti-TYRO3 Antibody Target Details TYRO3 Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-TYRO3 Antibody Target Details TYRO3 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-TYRO3 Antibody Target Details TYRO3 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-TYRO3 antibody (TYRO3 Protein Tyrosine Kinase) (ABIN872341) Formalin-fixed and paraffin embedded rat brain labeled with Anti-TYRO3 Polyclonal Ant...