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|Application / Reactivity||Mouse (Murine)|
|Enzyme Immunoassay (EIA)||9 Antibodies|
|Flow Cytometry (FACS)||2 Antibodies|
|Functional Studies (Func)||2 Antibodies|
|Immunocytochemistry (ICC)||3 Antibodies|
|Immunofluorescence (IF)||4 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||22 Antibodies|
|Immunohistochemistry (IHC)||21 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||3 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||22 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies|
|Intracellular Flow Cytometry (ICFC)||2 Antibodies|
|Neutralization (Neut)||1 Antibodies|
|Western Blotting (WB)||65 Antibodies|
|Antigen||Vascular Endothelial Growth Factor A (VEGFA) Antibodies|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This VEGF antibody is un-conjugated Alternatives|
Intracellular Flow Cytometry (ICFC)
|6 references available|
|Supplier||Log in to see|
Product Details anti-VEGF AntibodyTarget Details VEGF Application Details Handling References for anti-VEGF Antibody (ABIN2665452) Images
|Purification||The antibody was purified by affinity chromatography.|
Target Details VEGFProduct Details anti-VEGF Antibody Application Details Handling References for anti-VEGF Antibody (ABIN2665452) Images back to top
|Alternative Name||VEGF-A (VEGFA Antibody Abstract)|
|Background||VEGF-A, also known as VEGF (vascular endothelial growth factor), is the founding member of the family including VEGF (VEGF-A), VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. Vascular endothelial growth factors (VEGFs) are a family of secreted polypeptides with a highly conserved receptor-binding cystine-knot structure similar to that of the platelet-derived growth factors.VEGF-A has important roles in mammalian vascular development and in diseases involving abnormal growth of blood vessels such as tumor-related angiogenesis.VEGF-A is produced by diverse cell types, including aortic vascular smooth muscle cells, keratinocytes, macrophages and many tumor cells. Oxygen tension is a key physiological regulator of VEGF-A gene expression.|
|Research Area||Cytokines, Growth Factors, Receptors, Immunology, Inflammation, Signaling|
Application DetailsProduct Details anti-VEGF Antibody Target Details VEGF Handling References for anti-VEGF Antibody (ABIN2665452) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-VEGF Antibody Target Details VEGF Application Details References for anti-VEGF Antibody (ABIN2665452) Images back to top
|Buffer||Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||The antibody solution should be stored undiluted between 2°C and 8°C.|
References for anti-VEGF Antibody (ABIN2665452)Product Details anti-VEGF Antibody Target Details VEGF Application Details Handling Images back to top
Kirsch, Riegelbauer, Tagwerker et al.: "The mTOR-inhibitor rapamycin mediates proteinuria in nephrotoxic serum nephritis by activating the innate immune response." in: American journal of physiology. Renal physiology, Vol. 303, Issue 4, pp. F569-75, 2012 (PubMed).
Lambrechts, Carmeliet: "VEGF at the neurovascular interface: therapeutic implications for motor neuron disease." in: Biochimica et biophysica acta, Vol. 1762, Issue 11-12, pp. 1109-21, 2006 (PubMed).
Tong, Yao: "Contribution of VEGF and PEDF to choroidal angiogenesis: a need for balanced expressions." in: Clinical biochemistry, Vol. 39, Issue 3, pp. 267-76, 2006 (PubMed).
Reinders, Sho, Izawa et al.: "Proinflammatory functions of vascular endothelial growth factor in alloimmunity." in: The Journal of clinical investigation, Vol. 112, Issue 11, pp. 1655-65, 2003 (PubMed).
Ferrara, Gerber, LeCouter: "The biology of VEGF and its receptors." in: Nature medicine, Vol. 9, Issue 6, pp. 669-76, 2003 (PubMed).
Shibuya: "Structure and function of VEGF/VEGF-receptor system involved in angiogenesis." in: Cell structure and function, Vol. 26, Issue 1, pp. 25-35, 2001 (PubMed).
ImagesProduct Details anti-VEGF Antibody Target Details VEGF Application Details Handling References for anti-VEGF Antibody (ABIN2665452) back to top