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anti-Rat (Rattus) VEGFC antibody for Immunohistochemistry

Recommended VEGFC Antibody (supplied by: Log in to see )

Antigen
Vascular Endothelial Growth Factor C (VEGFC) Antibodies
  • AW228853
  • Flt4-L
  • vegf-c
  • VEGF-C
  • VEGFC
  • VRP
  • xvegf-c
Reactivity
Human, Mouse (Murine), Rat (Rattus)
221
81
61
4
3
2
2
1
1
1
1
1
Host
Rabbit
170
104
8
1
Clonality
Polyclonal
Conjugate
This VEGFC antibody is un-conjugated
23
22
18
9
7
7
4
4
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
222
147
83
23
22
22
20
15
11
6
5
3
Supplier
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Available images

Catalog No. ABIN258871
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0011344259 ABIN1875325 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011344259 ABIN2424307 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0011344259 ABIN2405456 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011344259 ABIN2384515 IC IHC ELISA WB Rabbit IgG AA 108-223 Log in to see Polyclonal
0.0011344259 ABIN1172445 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
0.0011344259 ABIN1172446 ICC IF IHC WB FITC Rabbit IgG Log in to see Polyclonal
0.0011344259 ABIN2384541 IC IHC ELISA WB Mouse AA 108-223 Log in to see
0.0011344259 ABIN2973996 IHC WB Rabbit IgG Log in to see Polyclonal

Similar anti-VEGFC Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 53 Antibodies 25 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 3 Antibodies
Immunochromatography (IC) 2 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 3 Antibodies 1 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 9 Antibodies 21 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 60 Antibodies

General

Antigen Vascular Endothelial Growth Factor C (VEGFC) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(221), (81), (61), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(170), (104), (8), (1)
Clonality
Polyclonal
Conjugate This VEGFC antibody is un-conjugated
(23), (22), (18), (9), (7), (7), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
(222), (147), (83), (23), (22), (22), (20), (15), (11), (6), (5), (3)
Pubmed 7 references available
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Product Details anti-VEGFC Antibody

Target Details VEGFC Application Details Handling References for anti-VEGFC Antibody (ABIN258871) Images
Specificity This antibody recognizes rat VEGF-C and has strong cross-reactivity with mouse and human VEGF-C.
Cross-Reactivity (Details) Not yet tested in other species.
Purification Protein G purified
Immunogen This antibody was produced by immunizing rabbits with purified rat VEGF-C recombinant protein.
Isotype IgG

Target Details VEGFC

Product Details anti-VEGFC Antibody Application Details Handling References for anti-VEGFC Antibody (ABIN258871) Images back to top
Antigen
Alternative Name VEGF-C (VEGFC Antibody Abstract)
Background Vascular endothelial growth factors (VEGFs), also known as vasculotropins, are a familyof closely related growth factors having a conserved pattern of eight cysteine residuesand sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelialcells, induce angiogenesis, promote cell migration, increase vascular permeability, andinhibit apoptosis. The mitogenic activity of VEGFs appears to be mediated by specificVEGF receptors. The target cell specificity of VEGF is restricted to vascular endothelialcells. Vascular Endothelial Growth Factor C (VEGFC) is a member of the VEGFsubfamily of PDGF-related growth factors. It is the ligand for Flt4 (VEGFR3) and KDR(VEGFR2). VEGFC binds Flt4 and induces tyrosine autophosphorylation of VEGFR3and VEGFR2. VEGFC also stimulates the migration of bovine capillary endothelial cellsin collagen gel. It is a specific growth factor for the lymphatic vascular system andmediates lymphangiogenesis. VEGFC is abundantly expressed in heart and skeletalmuscle. Other tissues such as lung and kidney also express VEGFC. The humanVEGFC gene is located on chromosome 4q34. Alternate Names: Anti-Flt 4L antibody, Anti-Flt4 L antibody, Anti-Flt4 ligand antibody, Anti-FLT4 ligandDHM antibody, Anti-Flt4L antibody, Anti-MGC136707 antibody, Anti-VascularEndothelial Growth Factor C antibody, Anti-Vascular endothelial growth factor relatedprotein antibody, Anti-VEGF C antibody, Anti-VEGF-C antibody, Anti-VRP antibody.
Gene Symbol: VEGFC
Gene ID 7424, 22341, 114111
Research Area Cytokines, Growth Factors, Receptors, Immunology, Inflammation, Signaling
Pathways RTK Signaling

Application Details

Product Details anti-VEGFC Antibody Target Details VEGFC Handling References for anti-VEGFC Antibody (ABIN258871) Images back to top
Application Notes This antibody recognizes rat VEGF-C and has strong cross-reactivity with mouse and human VEGF-C. IHC for this antibody been tested in the following condition with good results: 1) Fixation: 4% PFA Fixation at 4 degree Overnight 2) Antigen Retrieval: 20ug/ml proteinase K (room temperature 15-25 min) 3) Primary antibody: 1:50-200 (after re-dissolving the antibody in 500ul PBS) 4 degree overnight or room temperature (if signal is weak). Immunohistochemistry-Frozen was reported in scientific literature.
Recommended dilutions: Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, Immunohistochemistry-Paraffin 1:50-1:200, Western Blot 1:500-1:1000
Restrictions For Research Use only

Handling

Product Details anti-VEGFC Antibody Target Details VEGFC Application Details References for anti-VEGFC Antibody (ABIN258871) Images back to top
Format Lyophilized
Reconstitution Reconstitute the antibody with 500 µL sterile PBS and the final concentration is 200 µg/mL.
Buffer Lyophilized from PBS.
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Aliquot and store at -20 °C or -80 °C.

References for anti-VEGFC Antibody (ABIN258871)

Product Details anti-VEGFC Antibody Target Details VEGFC Application Details Handling Images back to top
Product cited in:

de Sousa, Lourenço, de Moraes, Vartanian, Gonçalves-Filho, Kowalski, Soares, Coutinho-Camillo: "Head and neck squamous cell carcinoma lymphatic spread and survival: Relevance of vascular endothelial growth factor family for tumor evaluation." in: Head & neck, Vol. 37, Issue 10, pp. 1410-6, 2015 (Sample species: Human). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Yoshida, Hamuy, Hamada, Yoshimoto, Hirano, Akita: "Adipose-derived stem cell transplantation for therapeutic lymphangiogenesis in a mouse secondary lymphedema model." in: Regenerative medicine, Vol. 10, Issue 5, pp. 549-62, 2015 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Xu, Franchi, Miller, Crane, Peterson, Psaltis, Harris, Lerman, Rodriguez-Porcel: "Polycystic kidneys have decreased vascular density: a micro-CT study." in: Microcirculation (New York, N.Y. : 1994), Vol. 20, Issue 2, pp. 183-9, 2013

Kono, Watanabe, Abukawa, Hasegawa, Satomi, Chikazu: "Cyclo-oxygenase-2 expression is associated with vascular endothelial growth factor C expression and lymph node metastasis in oral squamous cell carcinoma." in: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, Vol. 71, Issue 10, pp. 1694-702, 2013 (Sample species: Human). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Zampell, Yan, Avraham, Daluvoy, Weitman, Mehrara: "HIF-1α coordinates lymphangiogenesis during wound healing and in response to inflammation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 3, pp. 1027-39, 2012

Zampell, Yan, Elhadad, Avraham, Weitman, Mehrara: "CD4(+) cells regulate fibrosis and lymphangiogenesis in response to lymphatic fluid stasis." in: PLoS ONE, Vol. 7, Issue 11, pp. e49940, 2012 (Sample species: Mouse (Murine)). Further details: Western Blotting,Immunohistochemistry (Frozen Sections)

Ostalska-Nowicka, Malinska, Zabel, Witkiewicz, Nowicki: "Nephrotic syndrome unfavorable course correlates with downregulation of podocyte vascular endothelial growth factor receptor (VEGFR)-2." in: Folia histochemica et cytobiologica, Vol. 49, Issue 3, pp. 472-8, 2011 (Sample species: Human).

Images

Product Details anti-VEGFC Antibody Target Details VEGFC Application Details Handling References for anti-VEGFC Antibody (ABIN258871) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-VEGFC antibody (Vascular Endothelial Growth Factor C) (ABIN258871) anti-Vascular Endothelial Growth Factor C (VEGFC) antibody