anti-Mouse (Murine) VEGFR2 antibody for Blocking Reagent

Recommended VEGFR2 Antibody (supplied by: Log in to see )

Antigen
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
  • vegfr-2
  • KDR
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • VEGFR2
  • sVEGFR-2
  • Vegfr-2
  • CD309
  • FLK1
  • VEGFR
  • FLK-1
  • flk-1
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • fk52c05
  • flk
  • kdr
  • kdra
  • vegfr2
  • vegfr4
  • vegr2
  • wu:fk52c05
  • vascular endothelial growth factor receptor 2
  • kinase insert domain protein receptor
  • kinase insert domain receptor
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • kinase insert domain receptor like
  • vascular endothelial growth factor receptor-2
  • vegfr-2
  • Kdr
  • KDR
  • kdr
  • kdrl
Reactivity
Mouse (Murine)
642
382
182
25
7
4
4
4
3
3
2
2
1
1
1
1
1
1
1
1
Host
Rat
544
162
69
6
2
2
1
Clonality
Monoclonal
Conjugate
This VEGFR2 antibody is conjugated to Alexa Fluor 488
46
35
24
23
18
12
12
11
9
7
7
7
6
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
1
1
Application
Blocking Reagent (BR), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)
472
243
233
217
125
109
44
33
26
25
19
17
14
12
11
8
8
6
5
1
1
1
1
1
1
1
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Catalog No. ABIN2657390
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2657391 BR FACS IP IHC Alexa Fluor 488 Rat IgG2a kappa Log in to see Avas12 7

General

Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
Reactivity Mouse (Murine)
(642), (382), (182), (25), (7), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rat
(544), (162), (69), (6), (2), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This VEGFR2 antibody is conjugated to Alexa Fluor 488
(46), (35), (24), (23), (18), (12), (12), (11), (9), (7), (7), (7), (6), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1)
Application Blocking Reagent (BR), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)
(472), (243), (233), (217), (125), (109), (44), (33), (26), (25), (19), (17), (14), (12), (11), (8), (8), (6), (5), (1), (1), (1), (1), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-VEGFR2 Antibody

Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN2657390) Images
Purification The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
Clone Avas12
Isotype IgG2a kappa

Target Details VEGFR2

Product Details anti-VEGFR2 Antibody Application Details Handling References for anti-VEGFR2 antibody (ABIN2657390) Images back to top
Antigen
Alternative Name CD309 (KDR Antibody Abstract)
Background CD309 is also known as vascular endothelial growth factor receptor 2 (VEGFR2) and fetal liver kinase-1 (Flk-1). CD309 is a member of the tyrosine protein kinase family that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. CD309 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle. It's a receptor for VEGF or VEGFC, and plays an important role in the development of vascular endothelial cells, hematopoietic cells, and vascular permeability.
Pathways RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling

Application Details

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling References for anti-VEGFR2 antibody (ABIN2657390) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details References for anti-VEGFR2 antibody (ABIN2657390) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C

References for anti-VEGFR2 antibody (ABIN2657390)

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling Images back to top
Background publications

Albiero, Poncina, Tjwa, Ciciliot, Menegazzo, Ceolotto, Vigili de Kreutzenberg, Moura, Giorgio, Pelicci, Avogaro, Fadini: "Diabetes causes bone marrow autonomic neuropathy and impairs stem cell mobilization via dysregulated p66Shc and Sirt1." in: Diabetes, Vol. 63, Issue 4, pp. 1353-65, 2014

Ishitobi, Matsumoto, Azami, Itoh, Itoh, Takahashi, Ema: "Flk1-GFP BAC Tg mice: an animal model for the study of blood vessel development." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 59, Issue 5, pp. 615-22, 2010

Nishikawa, Nishikawa, Kawamoto, Yoshida, Kizumoto, Kataoka, Katsura: "In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos." in: Immunity, Vol. 8, Issue 6, pp. 761-9, 1998

Kataoka, Takakura, Nishikawa, Tsuchida, Kodama, Kunisada, Risau, Kita, Nishikawa: "Expressions of PDGF receptor alpha, c-Kit and Flk1 genes clustering in mouse chromosome 5 define distinct subsets of nascent mesodermal cells." in: Development, growth & differentiation, Vol. 39, Issue 6, pp. 729-40, 1998

Shalaby, Ho, Stanford, Fischer, Schuh, Schwartz, Bernstein, Rossant: "A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis." in: Cell, Vol. 89, Issue 6, pp. 981-90, 1997

Kabrun, Bühring, Choi, Ullrich, Risau, Keller: "Flk-1 expression defines a population of early embryonic hematopoietic precursors." in: Development (Cambridge, England), Vol. 124, Issue 10, pp. 2039-48, 1997

Patterson, Perrella, Hsieh, Yoshizumi, Lee, Haber: "Cloning and functional analysis of the promoter for KDR/flk-1, a receptor for vascular endothelial growth factor." in: The Journal of biological chemistry, Vol. 270, Issue 39, pp. 23111-8, 1995

Images

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN2657390) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (Alexa Fluor 488) (ABIN2657390) anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (Alexa Fluor 488)