You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our WASL Proteins (WASL)

Full name:
Wiskott-Aldrich Syndrome-Like Proteins (WASL)
On www.antibodies-online.com are 7 Wiskott-Aldrich Syndrome-Like (WASL) Proteins from 4 different suppliers available. Additionally we are shipping WASL Antibodies (139) and WASL Kits (11) and many more products for this protein. A total of 167 WASL products are currently listed.
Synonyms:
2900021I12Rik, 3110031I02Rik, IMD2, N-WASP, NWASP, SCNX, THC, THC1, TRS4, U42471, WASL, Wasp, zgc:55478, zgc:77237
list all proteins Gene Name GeneID UniProt
WASL 7454 P42768
WASL 317371  
Mouse WASL WASL 22376 P70315

Show all synonyms

WASL Proteins (WASL) by Origin

Select your origin of interest

More Proteins for WASL Interaction Partners

Human Wiskott-Aldrich Syndrome-Like (WASL) interaction partners

  1. This suggests that N-WASP's failure to compensate for WASP in rescuing chemotaxis could be due to the absence of this I30 region.

  2. N-WASP is downregulated in clear cell renal cell carcinoma (show MOK Proteins)

  3. Studies indicate that mutations in the Wiskott-Aldrich syndrome protein (WASp) gene cause a continuum of clinical symptoms ranging from intermittent X-linked thrombocytopenia to full classical Wiskott-Aldrich syndrome (WAS).

  4. RTVP-1 (show GLIPR1 Proteins) regulates glioma cell spreading, migration and invasion and that these effects are mediated via interaction with N-WASP and by interfering with the inhibitory effect of hnRNPK (show HNRNPK Proteins) on the function of this protein.

  5. Platelet actin nodule formation is dependent on WASp and the ARP2 (show ACTR2 Proteins)/3 complex.

  6. Nck was the most potent activator of N-WASP-driven actin assembly.

  7. conclude that tyrosine phosphorylation of WIP is a crucial regulator of WASP stability and function as an actin-nucleation-promoting factor

  8. WASP, RUNX1 (show RUNX1 Proteins), and ANKRD26 genes are important for normal TPO (show THPO Proteins) signaling and the network underlying thrombopoiesis.

  9. The introduction of functional WASp by GT corrected the alterations of both central and peripheral B cell tolerance checkpoints. WASp plays an important role in the establishment and maintenance of B cell tolerance in humans.

  10. We describe two Malay patients with classical Wiskott-Aldrich Syndrome with two different mutations in the WASP gene

Mouse (Murine) Wiskott-Aldrich Syndrome-Like (WASL) interaction partners

  1. N-WASP expression in B lymphocytes is required for the development of autoimmunity of WAS (Wiskott-Aldrich syndrome) and may represent a novel therapeutic target in WAS.

  2. Data (including data from studies in knockout mice) suggest that Cnr1 (cannabinoid receptor 1 (show CNR1 Proteins)) activation impacts actin cytoskeleton polymerization/stability via Wasl in growth cones of developing neurons and in synaptic spines of mature neurons.

  3. Platelet actin nodule formation is dependent on WASp and the ARP2 (show AICDA Proteins)/3 complex. WASp(-/-) mouse blood displays impaired platelet aggregate formation at arteriolar shear rates.

  4. Our data suggests that the N-WASP-Arp2/3 actin polymerization machinery generates branched-actin arrays at an advanced stage of blood-testis barrier remodeling.

  5. Findings suggest that Wiskott-Aldrich syndrome protein (WASp) plays a crucial role in B10 cell development and that WASp-deficient B10 cells may contribute to autoimmunity in Wiskott-Aldrich syndrome.

  6. N-terminus of Cas (show CTNND1 Proteins) associates with the FAK (show PTK2 Proteins)-N-WASP complex at the protrusive edge of the cell and that the C-terminus of Cas (show CTNND1 Proteins) associates with the immobilized integrin-SFK cluster.

  7. These results strongly suggest that the association between the WASP N-terminal domain and Btk plays an important role in the TLR2-signaling pathway in macrophages.

  8. Toca-1 (show FNBP1L Proteins)(knockdown) cells have defects in formation of myotubes probably due to reduced activity of actin cytoskeleton regulators such as N-WASP.

  9. In the absence of Wiskott-Aldrich syndrome protein, effective hematopoietic stem cell mobilization is achieved.

  10. N-WASP plays a unique role in the down-regulation of BCR (show BCR Proteins) signaling at the cell surface.

Cow (Bovine) Wiskott-Aldrich Syndrome-Like (WASL) interaction partners

  1. N-WASP WWCA domains can processively attach to growing barbed-end bundles and increase their diffusion-limited elongation rate.

WASL Protein Profile

Protein Summary

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.

Alternative names and synonyms associated with WASL

  • Wiskott-Aldrich syndrome-like b (waslb)
  • Wiskott-Aldrich syndrome-like (wasl)
  • Wiskott-Aldrich syndrome-like (WASL)
  • Wiskott-Aldrich syndrome (WAS)
  • Wiskott-Aldrich syndrome (Was)
  • Wiskott-Aldrich syndrome homolog (human) (Was)
  • Wiskott-Aldrich syndrome-like (Wasl)
  • Wiskott-Aldrich syndrome-like (human) (Wasl)
  • 2900021I12Rik protein
  • 3110031I02Rik protein
  • IMD2 protein
  • N-WASP protein
  • NWASP protein
  • SCNX protein
  • THC protein
  • THC1 protein
  • TRS4 protein
  • U42471 protein
  • WASL protein
  • Wasp protein
  • zgc:55478 protein
  • zgc:77237 protein

Protein level used designations for WASL

Wiskott-Aldrich syndrome-like , Wiskott-Aldrich syndrome, like , neural Wiskott-Aldrich syndrome protein , Wiskott-Aldrich syndrome gene-like protein , eczema-thrombocytopenia , thrombocytopenia 1 (X-linked) , wiskott-Aldrich syndrome protein , Wiskott-Aldrich syndrome homolog , wiskott-Aldrich syndrome protein homolog , N-WASP

GENE ID SPECIES
394034 Danio rerio
407864 Xenopus (Silurana) tropicalis
417750 Gallus gallus
463688 Pan troglodytes
475213 Canis lupus familiaris
696556 Macaca mulatta
100171409 Pongo abelii
7454 Homo sapiens
317371 Rattus norvegicus
22376 Mus musculus
8976 Homo sapiens
682507 Rattus norvegicus
281577 Bos taurus
73178 Mus musculus
Selected quality suppliers for WASL Proteins (WASL)
Did you look for something else?