Browse our anti-DIAPH1 (DIAPH1) Antibodies

Full name:
anti-Diaphanous Homolog 1 (Drosophila) Antibodies (DIAPH1)
On www.antibodies-online.com are 67 Diaphanous Homolog 1 (Drosophila) (DIAPH1) Antibodies from 17 different suppliers available. Additionally we are shipping DIAPH1 Proteins (6) and DIAPH1 Kits (4) and many more products for this protein. A total of 84 DIAPH1 products are currently listed.
Synonyms:
D18Wsu154e, DFNA1, DIA1, Diap1, Diaph1, DIAPH2, DRF1, hDIA1, LFHL1, mKIAA4062, p140mDia
list all antibodies Gene Name GeneID UniProt
DIAPH1 307483  
DIAPH1 13367 O08808
DIAPH1 1729 O60610

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Top referenced anti-DIAPH1 Antibodies

  1. Human Polyclonal DIAPH1 Primary Antibody for WB - ABIN153169 : Minin, Kulik, Gyoeva, Li, Goshima, Gelfand: Regulation of mitochondria distribution by RhoA and formins. in Journal of cell science 2006 (PubMed)
    Show all 4 references for 153169

  2. Dog (Canine) Monoclonal DIAPH1 Primary Antibody for IF, IP - ABIN968212 : Li, Higgs: The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition. in Current biology : CB 2003 (PubMed)
    Show all 3 references for 968212

  3. Human Polyclonal DIAPH1 Primary Antibody for ICC, IF - ABIN153170 : Jewett, Fischer, Mead, Hackstadt: Chlamydial TARP is a bacterial nucleator of actin. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 2 references for 153170

  4. Human Polyclonal DIAPH1 Primary Antibody for IHC, IHC (p) - ABIN4305203 : Goel, Sienkiewicz, Picciani, Lee, Bhattacharya: Cochlin induced TREK-1 co-expression and annexin A2 secretion: role in trabecular meshwork cell elongation and motility. in PLoS ONE 2011 (PubMed)

More Antibodies against DIAPH1 Interaction Partners

Mouse (Murine) Diaphanous Homolog 1 (Drosophila) (DIAPH1) interaction partners

  1. these results uncover a novel role for mDia1 in Abeta (show APP Antibodies)-mediated synaptotoxicity and demonstrate that inhibition of MT dynamics and accumulation of PTMs (show PTMS Antibodies) are driving factors for the induction of tau-mediated neuronal damage.

  2. Small Molecule Inhibition of Ligand-Stimulated RAGE (show AGER Antibodies)-DIAPH1 Signal Transduction.

  3. Diaphanous-related formin (show DIAPH3 Antibodies) signaling plays a role in heart and vascular development and the maintenance of SMC (show DYM Antibodies) phenotype.

  4. Liprin-alpha3 (show PPFIA3 Antibodies) uses an alpha-helical region to bind to mDia1, counteracting mouse Dia1 (show CYB5R3 Antibodies) activation by RhoA (show RHOA Antibodies).

  5. Depleting FMNL1 (show FMNL1 Antibodies), another Formin (show FMN1 Antibodies) family member, resulted in reduced mDia1 expression, while RhoA (show RHOA Antibodies) inhibition did not alter mDia1 expression, which indicated that there was a FMNL1 (show FMNL1 Antibodies)-mDia1-Profilin1 (show PFN1 Antibodies) signaling pathway in mouse oocytes.

  6. Mechanistically, mDia1 deficiency led to a downregulation of membrane-associated genes and a specific upregulation of CD14 (show CD14 Antibodies) messenger RNA in granulocytes, but not in other lineages.

  7. Mammalian diaphanous-related formin 1 regulates GSK3beta (show GSK3b Antibodies)-dependent microtubule dynamics required for T cell migratory polarization.

  8. mDia1 can efficiently put actin filaments under mechanical tension.

  9. The active form of mDia1 localized to the apical membrane in exocrine pancreas cells; introduction of an active form of mDia1 leads to a marked increase in actin bundle density along the secretory vesicle lumen perimeter.

  10. Dia1 (show CYB5R3 Antibodies) and Dia2 (show DIAPH3 Antibodies) are dynamic components of meiotic spindle and pole complex during meiotic maturation of oocytes.

Human Diaphanous Homolog 1 (Drosophila) (DIAPH1) interaction partners

  1. Ligand-induced association of RAGE (show AGER Antibodies) homodimers on the cell surface increases the molecular dimension of the receptor, recruiting DIAPH1 and activating signaling pathways.

  2. The authors describe a novel patient-derived DIAPH1 mutation (c.3610C>T) in two unrelated families, which results in early termination prior to a basic amino acid motif (RRKR(1204-1207)) at the DAD C-terminus. The mutant DIA1 (show CYB5R3 Antibodies)(R1204X) disrupted the autoinhibitory DID-DAD interaction and was constitutively active.

  3. The description of a novel disorder of platelet formation and hearing loss extends the repertoire of DIAPH1-related disease, and provides new insight into the autoregulation of DIAPH1 activity.

  4. Studies indicate that diaphanous related formin 1 (DIAPH1) is essentially involved in microtubules (MTs (show TIMM8A Antibodies))-dependent early adhesion of colon cancer cells.

  5. A 51-year-old patient in a Korean family with ADNSHL was examined by pure-tone audiometry, and genetic analysis of DIAPH1 was performed. A novel variant, p.I530S (c.1589T > G), was identified in the DIAPH1 gene, and the mutation was located in the highly conserved coiled-coil domain of the DIA1 (show CYB5R3 Antibodies) protein.

  6. mDia1 is an important regulator of breast cancer cell invasion and that its effects may be mediated by MMP-2 (show MMP2 Antibodies) activity.

  7. Findings suggest that regulation of cellular trafficking and microtubule-mediated localization of MT1-MMP (show MMP14 Antibodies) by mDia1 is likely important in breast cancer invasion through the expression of cancer stem cell genes.

  8. Loss-of-function variants in DIAPH1 is associated with syndromic microcephaly, blindness, and early onset seizures.

  9. functional complementation experiments and optogenetics to show that mDia1 cooperates with the Arp2 (show ACTR2 Antibodies)/3 complex in initiating lamellipodia and ruffles.

  10. Capping protein and dia1 (show CYB5R3 Antibodies) functionally coregulate filament barbed-end assembly.

DIAPH1 Antigen Profile

Antigen Summary

This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with DIAPH1

  • diaphanous homolog 1 (Drosophila) (DIAPH1) antibody
  • diaphanous-related formin 1 (DIAPH1) antibody
  • diaphanous-related formin 1 (diaph1) antibody
  • diaphanous-related formin 1 (Diaph1) antibody
  • diaphanous homolog 1 (Drosophila) (diaph1) antibody
  • diaphanous homolog 1 (Drosophila) (Diap1) antibody
  • D18Wsu154e antibody
  • DFNA1 antibody
  • DIA1 antibody
  • Diap1 antibody
  • Diaph1 antibody
  • DIAPH2 antibody
  • DRF1 antibody
  • hDIA1 antibody
  • LFHL1 antibody
  • mKIAA4062 antibody
  • p140mDia antibody

Protein level used designations for DIAPH1

diaphanous homolog 1 (Drosophila) , diaphanous homolog 1 , diaphanous homolog 2 , protein diaphanous homolog 1 , protein diaphanous homolog 1-like , diaphanous-related formin-1 , mDIA1

GENE ID SPECIES
100684883 Canis lupus familiaris
700918 Macaca mulatta
786565 Bos taurus
733754 Xenopus (Silurana) tropicalis
100072186 Equus caballus
374040 Gallus gallus
307483 Rattus norvegicus
100457442 Pongo abelii
100478130 Ailuropoda melanoleuca
100562222 Anolis carolinensis
13367 Mus musculus
1729 Homo sapiens
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