Browse our anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) Antibodies

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anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog Antibodies (FGR)
On www.antibodies-online.com are 126 Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) Antibodies from 21 different suppliers available. Additionally we are shipping Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog Proteins (12) and Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog Kits (4) and many more products for this protein. A total of 153 Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog products are currently listed.
Synonyms:
c-fgr, c-src2, p55-Fgr, p55c-fgr, p58-Fgr, p58c-fgr, SRC2

Most Popular Reactivities for anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) Antibodies

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All available anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog Antibodies

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Top referenced anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog Antibodies

  1. Human Monoclonal FGR Primary Antibody for IHC, ELISA - ABIN969143 : Heneghan, Connaghan-Jones, Miura, Bain: Coactivator assembly at the promoter: efficient recruitment of SRC2 is coupled to cooperative DNA binding by the progesterone receptor. in Biochemistry 2007 (PubMed)
    Show all 2 references for 969143

  2. Human Polyclonal FGR Primary Antibody for IF, IHC (p) - ABIN392096 : Tatarov, Mitchell, Seywright, Leung, Brunton, Edwards: SRC family kinase activity is up-regulated in hormone-refractory prostate cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2009 (PubMed)
    Show all 2 references for 392096

  3. Mouse (Murine) Polyclonal FGR Primary Antibody for ELISA, WB - ABIN257661 : Katamine, Notario, Rao, Miki, Cheah, Tronick, Robbins: Primary structure of the human fgr proto-oncogene product p55c-fgr. in Molecular and cellular biology 1988 (PubMed)

  4. Human Polyclonal FGR Primary Antibody for ELISA, WB - ABIN1533078 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)

More Antibodies against Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog Interaction Partners

Human Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) interaction partners

  1. we provide evidence for involvement of HCK (show HCK Antibodies) and FGR in FCRL4 (show FCRL4 Antibodies)-mediated immunoregulation and for the functional importance of posttranslational modifications of the FCRL4 (show FCRL4 Antibodies) molecule.

  2. Data indicate that combined treatment using SFK (LYN (show LYN Antibodies), HCK (show HCK Antibodies), or FGR) and c-KIT (show KIT Antibodies) inhibitor dasatinib dasatinib and chemotherapy provides a novel approach to increasing p53 (show TP53 Antibodies) activity and enhancing targeting of acute myeloid leukemia (show BCL11A Antibodies) (AML (show RUNX1 Antibodies)) stem cells.

  3. Fgr plays a biologically significant role in ovarian cancer growth and might represent an important target

  4. Recruitment of the coactivator, SRC2 (show NCOA2 Antibodies), is coupled to cooperative DNA binding by the progesterone receptor (show PGR Antibodies).

Mouse (Murine) Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) interaction partners

  1. the Hck (show HCK Antibodies), Fgr and Lyn (show LYN Antibodies) kinases are also necessary for amastigote uptake by macrophages. Src (show SRC Antibodies)-mediated Arg activation is required for efficient uptake.

  2. Data indicate that Src (show SRC Antibodies)-Family Kinases Hck (show HCK Antibodies) and Fgr regulate cytokine secretion by macrophages.

  3. Fgr is not only are progressively overexpressed in atherosclerosis, but it also controls critical molecular processes in monocyte influx, blood monocyte subset balance, macrophage accumulation, and the maintenance of atherosclerotic lesion stability.

  4. Ablation of Fgr abolishes the capacity of mitochondria to adjust metabolism upon nutrient restriction, hypoxia/reoxygenation, and T cell activation, demonstrating the physiological relevance of this adaptive response.

  5. The Src (show SRC Antibodies) family kinases Hck (show HCK Antibodies), Fgr, and Lyn (show LYN Antibodies) are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.

  6. The Src family kinase Fgr is critical for activation of mast cells and IgE-mediated anaphylaxis in mice.

  7. Despite possessing enhanced killing, alveolar macrophage Fgr/Hck (show HCK Antibodies)/Lyn (show LYN Antibodies)-deficient ("triple-knockout") mice do not demonstrate enhanced inflammatory responses to Pneumocystis murina.

  8. Hck and Fgr function as negative regulators of myeloid cell chemokine signaling by maintaining the tonic phosphorylation of PIR-

  9. interaction of MIST (show CLNK Antibodies) with Fgr, mediated by the C-terminal proline-rich region of MIST (show CLNK Antibodies) and the SH3 domain (show ITSN1 Antibodies) of Fgr, was required for the suppression of NK-cell receptor (show KLRD1 Antibodies)-induced IFN-gamma (show IFNG Antibodies) production

  10. Fgr plays no role in chemoattractant-induced, inside-out beta 2 integrin activation of neutrophils but regulates their outside-in, signaling-dependent sustained adhesion.

Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) Antigen Profile

Antigen Summary

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alternative names and synonyms associated with Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR)

  • Fibroblast growth factor receptor 1 (Fgfr1) antibody
  • Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog (FGR) antibody
  • feline Gardner-Rasheed sarcoma viral oncogene (Fgr) antibody
  • feline Gardner-Rasheed sarcoma viral oncogene homolog (FGR) antibody
  • Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog (Fgr) antibody
  • c-fgr antibody
  • c-src2 antibody
  • p55-Fgr antibody
  • p55c-fgr antibody
  • p58-Fgr antibody
  • p58c-fgr antibody
  • SRC2 antibody

Protein level used designations for FGR

FGF receptor-1 , FGFR-1 , MFR , bFGF-R , bFGF-R-1 , basic fibroblast growth factor receptor 1 , c-fgr , fibroblast growth factor receptor 1 , proto-oncogene c-Fgr , tyrosine-protein kinase Fgr , proto-oncogene tyrosine-protein kinase FGR , Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog , tyrosine-protein kinase Fgr-like , Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog , proto-oncogene tyrosine-protein kinase Fgr , c-fgr protooncogene , c-src-2 proto-oncogene , p55-c-fgr protein , v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog , p55-Fgr

GENE ID SPECIES
79114 Rattus norvegicus
516133 Bos taurus
716296 Macaca mulatta
739516 Pan troglodytes
100442468 Pongo abelii
100467541 Ailuropoda melanoleuca
79113 Rattus norvegicus
2268 Homo sapiens
14191 Mus musculus
487341 Canis lupus familiaris
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