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Browse our GABRB3 Proteins (GABRB3)

Full name:
gamma-aminobutyric Acid (GABA) A Receptor, beta 3 Proteins (GABRB3)
On are 7 gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) Proteins from 2 different suppliers available. Additionally we are shipping GABRB3 Antibodies (102) and many more products for this protein. A total of 116 GABRB3 products are currently listed.
A230092K12Rik, AW049585, beta3, Cp1, ECA5, Gabrb-3, GABRB3, LOC100230475
list all proteins Gene Name GeneID UniProt
GABRB3 2562 P28472
Rat GABRB3 GABRB3 24922 P63079
GABRB3 14402 P63080

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Human gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) interaction partners

  1. Results indicate that GABRB3 mutations are associated with a broad phenotypic spectrum of epilepsies and that reduced receptor function causing GABAergic disinhibition represents the relevant disease mechanism

  2. GABRB3 might be associated with heroin dependence, and increased expression of GABRB3 might contribute to the pathogenesis of heroin dependence

  3. Findings provide genetic evidence for the involvement of the genes GABRB3 and GABRA5 (show GABRA5 Proteins) in the susceptibility to panic disorder

  4. Increased GABRB3 expression may confer an increased risk of schizophrenia.

  5. 1,2-dichlorohexafluorocyclobutane enhancement of GABRA5 (show GABRA5 Proteins) activity is abolished by GABRB3 mutations.

  6. Propofol, AziPm, and o-PD Inhibit [3H]Azietomidate and R-[3H]mTFD-MPAB Photolabeling of alpha1beta3 GABAAR (show GABRG2 Proteins).

  7. Considering our Argentinean ASD sample, it can be inferred that GABRB3 would be involved in the etiology of autism through interaction with GABRD. These results support the hypothesis that GABAR subunit genes are involved in autism.

  8. Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human alpha1beta3gamma2 gamma-aminobutyric acid type A (GABAA (show GABRg1 Proteins)) receptor.

  9. With a weak association, data do not support the hypothesis that the GABRB3 variants are a cause of nonsyndromic cleft lip and/or palate

  10. results provide additional evidence that GABRB3 and MAOB (show MAOB Proteins)/NDP (show NDP Proteins) gene regions might constitute risk factors for hallucinations and delusions in schizophrenia.

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) interaction partners

  1. Dysregulation of fragile X mental retardation protein (show NUFIP2 Proteins)-metabotropic glutamate receptor 5 (show GRM5 Proteins) signaling pathway, accompanied with a downregulation of GABA(A) receptor beta3 subunit expression, may contribute to the 'autistic-like' features knockout mice.

  2. The data presented here support the hypothesis that alpha5beta3-GABAARs underlie tonic inhibition in hippocampal CA1 (show CA1 Proteins) pyramidal cells

  3. These studies identify a novel gephyrin (show GPHN Proteins)-binding motif in GABA(A) R beta2 and beta3 large cytoplasmic loops.

  4. Data indicate that the expression levels of [beta]2/3 GABAAR (show GABRG2 Proteins) showed 2.81 +/- 0.08-fold and 3.83 +/- 0.07-fold increases, respectively, in the pancreatectomized mice 3 and 14 days after surgery.

  5. It was show nthat activation of L-type voltage-gated Ca2 (show CA2 Proteins)+ channels leads to Ca2+/calmodulin-dependent protein kinase II (show CAMK2G Proteins) phosphorylation of S383 within the beta3 subunit of the GABAA (show GABRg1 Proteins) receptor.

  6. The endogenous sleep pathway in the hypothalamus operates through the beta1- containing GABAAR (show GABRG2 Proteins) whereas inhibition of neuronal firing (anaesthesia) by low propofol doses relies on beta3- containing GABAAR (show GABRG2 Proteins).

  7. Suggest that forebrain Gabrb3 contributes to hippocampal-dependent memory suppression by isoflurane, but not etomidate.

  8. Mice heterozygous for Gabrb3 exhibited an increase in seizure susceptibility and sensitivity to touch and heat.

  9. Differential cell surface expression of GABAA (show GABRg1 Proteins) receptor alpha1, alpha6, beta2 and beta3 subunits in cultured mouse cerebellar granule cells influence of cAMP-activated signalling.

  10. morphologic alterations in the spiral ganglion and Scarpa's ganglion from gamma-aminobutyric acid A (GABA(A)) receptor beta(3) subunit null mutant mice

GABRB3 Protein Profile

Protein Summary

This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with GABRB3

  • gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3)
  • gamma-aminobutyric acid (GABA) A receptor, beta 3 (gabrb3)
  • gamma-aminobutyric acid (GABA) A receptor, beta 3 (LOC100230475)
  • gamma-aminobutyric acid (GABA) A receptor, beta 3 (Gabrb3)
  • gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 (Gabrb3)
  • A230092K12Rik protein
  • AW049585 protein
  • beta3 protein
  • Cp1 protein
  • ECA5 protein
  • Gabrb-3 protein
  • GABRB3 protein
  • LOC100230475 protein

Protein level used designations for GABRB3

gamma-aminobutyric acid (GABA) A receptor, beta 3 , gamma-aminobutyric acid receptor subunit beta-3 , gamma-aminobutyric acid A receptor beta 3 , gamma-aminobutyric acid receptor subunit beta-3-like , GABA-alpha receptor beta-2 subunit , GABAA receptor beta-3 subunit , GABA(A) receptor subunit beta-3 , Gamma-aminobutyric acid receptor beta 3 , gamma-aminobutyric acid (GABA-A) receptor, subunit beta 3 , gamma-aminobutyric acid receptor, subunit beta 3 , testis gamma-aminobutyric acid receptor subunit beta 3 , GABA-A receptor beta-3 subunit , cleft palate 1

453265 Pan troglodytes
711754 Macaca mulatta
100050803 Equus caballus
100124708 Xenopus (Silurana) tropicalis
100171629 Pongo abelii
100230475 Taeniopygia guttata
100286790 Felis catus
100470111 Ailuropoda melanoleuca
100587224 Nomascus leucogenys
2562 Homo sapiens
24922 Rattus norvegicus
606913 Canis lupus familiaris
529593 Bos taurus
566922 Danio rerio
396290 Gallus gallus
14402 Mus musculus
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