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anti-Human GLUT1 Antibodies:
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Human Polyclonal GLUT1 Primary Antibody for ELISA, ICC - ABIN152817
Minamishima, Moslehi, Bardeesy, Cullen, Bronson, Kaelin: Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure. in Blood 2008
Show all 18 Pubmed References
Human Polyclonal GLUT1 Primary Antibody for ChIP, FACS - ABIN258123
Hergovich, Lisztwan, Thoma, Wirbelauer, Barry, Krek: Priming-dependent phosphorylation and regulation of the tumor suppressor pVHL by glycogen synthase kinase 3. in Molecular and cellular biology 2006
Show all 14 Pubmed References
Human Monoclonal GLUT1 Primary Antibody for CyTOF, FACS - ABIN4899145
Jain, Manuel, Khan, Ahuja, Quann, Wigdahl: DC-SIGN mediates cell-free infection and transmission of human T-cell lymphotropic virus type 1 by dendritic cells. in Journal of virology 2009
Show all 7 Pubmed References
Human Monoclonal GLUT1 Primary Antibody for FACS - ABIN4895661
Patsoukis, Bardhan, Chatterjee, Sari, Liu, Bell, Karoly, Freeman, Petkova, Seth, Li, Boussiotis: PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation. in Nature communications 2015
Show all 4 Pubmed References
Human Monoclonal GLUT1 Primary Antibody for IHC (p), WB - ABIN1688139
Demel, Feuerecker, Piontek, Seidl, Blechert, Pickhard, Essler: Effects of topoisomerase inhibitors that induce DNA damage response on glucose metabolism and PI3K/Akt/mTOR signaling in multiple myeloma cells. in American journal of cancer research 2015
Show all 2 Pubmed References
Human Polyclonal GLUT1 Primary Antibody for FACS, ICC - ABIN5076961
Rodríguez-Espinosa, Rojas-Espinosa, Moreno-Altamirano, López-Villegas, Sánchez-García: Metabolic requirements for neutrophil extracellular traps formation. in Immunology 2015
Show all 2 Pubmed References
Human Monoclonal GLUT1 Primary Antibody for FACS - ABIN4895663
Prost, Relouzat, Spentchian, Ouzegdouh, Saliba, Massonnet, Beressi, Verhoeyen, Raggueneau, Maneglier, Castaigne, Chomienne, Chrétien, Rousselot, Leboulch: Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists. in Nature 2015
Show all 2 Pubmed References
Human Polyclonal GLUT1 Primary Antibody for IHC, ELISA - ABIN1582249
Wang, Li, Gao, Lu, Zhang, Ma, Ye, Zhang: Cardiotrophin-1 (CTF1) ameliorates glucose-uptake defects and improves memory and learning deficits in a transgenic mouse model of Alzheimer's disease. in Pharmacology, biochemistry, and behavior 2013
Human Monoclonal GLUT1 Primary Antibody for FACS - ABIN4895659
Palmer, Ostrowski, Gouillou, Tsai, Yu, Zhou, Henstridge, Maisa, Hearps, Lewin, Landay, Jaworowski, McCune, Crowe: Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection. in AIDS 2014
UCP2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreatic cancer cells to glycolysis inhibition.
ablation of Glut1 attenuated apoptosis and increased drug resistance via upregulation of p-Akt (show AKT1 Antibodies)/p-GSK-3beta (show GSK3b Antibodies) (Ser9)/beta-catenin (show CTNNB1 Antibodies)/survivin (show BIRC5 Antibodies).
Data show that SALL4 (show SALL4 Antibodies) promotes the expression of Glut1 and open chromatin through a HP1alpha (show CBX5 Antibodies)-dependent mechanism.
Results show that PPARalpha (show PPARA Antibodies) directly targeted the consensus PPRE motif of Glut1 promoter region resulting in Glut1 transcription repression leding to decreased influx of glucose in cancer cells.
Strong GLUT1 staining was inversely associated with circulating levels of fasting glucose in high grade serous ovarian cancer.
Results show that resistin (show RETN Antibodies) down-regulates the transcription of GLUT1 by suppressing the expression of PPARG (show PPARG Antibodies), thus causing impaired glucose transportation in endothelial cell layers.
Metabolically active CD4 (show CD4 Antibodies)+ T cells expressing Glut1 and OX40 (show TNFRSF4 Antibodies) preferentially harbor HIV during in vitro infection.
we found that PPARdelta (show PPARD Antibodies) directly regulated neutral amino acid transporter (show SLC6A19 Antibodies) SLC1 (show MCHR1 Antibodies)-A5 (solute carrier family 1 member 5 (show SLC1A5 Antibodies)) and glucose transporter-1 (Glut1) gene transcription, leading to uptake of glucose and amino acid, activation of mTOR (show FRAP1 Antibodies) signaling, and tumor progression. In contrast, silence of PPARdelta (show PPARD Antibodies) or its antagonist inhibited this event.
SLC2A1/GLUT1 is expressed late in the adenoma-carcinoma sequence during carcinogenesis in intraductal papillary mucinous neoplasms of the pancreas.
Paraoxonase 2 (show PON2 Antibodies) facilitates pancreatic ductal cancer growth and metastasis by stimulating GLUT1-mediated glucose transport.
GLUT1 may play an important role in Prostate Cancer progression via mediating glycolysis and proliferation. There is potential crosstalk between GLUT1-mediated glycolysis and androgen sensitivity in Prostate Cancer.
ARAP2 (show ARAP2 Antibodies) knockdown did not affect fatty acid uptake but reduced basal glucose uptake, total levels of the glucose transporter GLUT1, and GLUT1 levels in the plasma membrane and the lipid micro-domain fraction.
TBC1D5 (show TBC1D5 Antibodies) shuttling to autophagosomes during metabolic stress facilitates retromer-dependent GLUT1 trafficking.
inhibition of GLUT1 activity and/or expression is shown to impair TGF-beta (show TGFB1 Antibodies)-driven fibrogenic processes, including cell proliferation and production of profibrotic mediators
B cell leukemia-induced inhibition of T cell Akt (show AKT1 Antibodies)/mTORC1 signaling and glucose metabolism drives T cell dysfunction; metabolic defects included reduced Akt (show AKT1 Antibodies)/mammalian target of rapamycin (show FRAP1 Antibodies) complex 1 (mTORC1) signaling, decreased expression of the glucose transporter Glut1 and hexokinase 2 (show HK2 Antibodies), and reduced glucose uptake
This study demonstrates a strict requirement for GLUT1 in the early stages of mammary tumorigenesis in vitro and in vivo.
GLUT1-dependent glycolysis regulates fibrogenesis in aged lung.
Data (including data from studies using transgenic mice) suggest that Glut1 (glucose transporter type 1) is a critical downstream target of Hif1a (hypoxia-inducible factor 1 (show HIF1A Antibodies), alpha subunit (show POLG Antibodies)) mediating hyperglycemia-induced extracellular matrix accumulation in kidney via regulation of Nox4 (show NOX4 Antibodies) (NADPH oxidase (show NOX1 Antibodies) type 4) expression in nephropathy due to diabetes type 1.
CRISPR/Cas9-mediated disruption of the Hdac2 gene increased Slc2a1 expression, suggesting that it is one of the responsible histone deacetylases (HDACs). These results confirm that b-OHB is a HDAC inhibitor and show that b-OHB plays an important role in fasting-induced epigenetic activation of a glucose transporter gene in the brain.
Taken together, the data suggest that curcumin binds directly to GLUT1 at a site that overlaps with the cytochalasin B binding site and thereby inhibits glucose transport.
Glut-1 expression globally depended on histological subtypes and the staining patterns (diffuse or zonal) were different between thymic carcinomas and type B3 thymomas
Glut-1 glucose transporter expression in esophageal squamous cell carcinoma is associated with tumor aggressiveness.
Glucose transporter 1 transcript levels were higher in the right ventricle than the left ventricle.
pGlcT, together with MEX1, contributes significantly to the export of starch degradation products from chloroplasts in A. thaliana leaves and and that this starch-mediated pathway for photoassimilate export via pGlcT and MEX1 is essential for the growth and development of A. thaliana. [pGlcT]
Low GLUT1 and GLUT3 (show SLC2A3 Antibodies) expression in nonclassical monocytes was unaltered during differentiation into macrophages. GLUT4 (show SLC2A4 Antibodies) mRNA was only detectable in unstimulated macrophages. Neither monocytes nor macrophages were insulin (show INS Antibodies) responsive.
the different conformations of the GLUT-1 transporter in luminal (blood facing) and abluminal (brain facing) membranes of bovine cerebral endothelial cells arise from differential phosphorylation of GLUT-1
Significant increases in GLUT1 gene expression were observed during early lactation.
Hyperthermia-induced Hsp90 (show HSP90 Antibodies).eNOS (show NOS3 Antibodies) preserves mitochondrial respiration in hyperglycemic endothelial cells by down-regulating Glut-1 and up-regulating G6PD (show G6PD Antibodies) activity.
distinct domains of the glucose transporter GLUT1 mediate HTLV envelope binding and virus entry
Expression of GLUT1 was evaluated in LLC-PK1 cells grown on porous membranes for the development of an artificial kidney.
results suggest that glucose is transported to the axonal cleft intracytoplasmically and delivered to the cleft by GLUT1 transporters
This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia.
, glucose transporter type 1, erythrocyte/brain
, hepG2 glucose transporter
, human T-cell leukemia virus (I and II) receptor
, solute carrier family 2, facilitated glucose transporter member 1
, solute carrier family 2, member 1
, Solute carrier family 2 a 1 (facilitated glucose transporter) brain
, Solute carrier family 2, facilitated glucose transporter member 1
, glucose transporter
, glucose transporter 1
, lethal (3) S007412
, solute carrier family 2 (facilitated glucose transporter), member 1
, solute carrier family 2 member 1
, excitatory amino acid transporter 1
, glial glutamate transporter
, glutamate transporter
, glutamate/aspartate transporter
, sodium-dependent glutamate/aspartate transporter 1
, solute carrier family 1, member 3
, glucose transporter protein
, glucose transporter type 1
, solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog
, glucose transport protein