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Upregulation of leptin (show LEP ELISA Kits) levels in both the vessel wall and the circulation after vessel injury promoted the migration of Sca-1(+) progenitor cells via leptin receptor (show LEPR ELISA Kits)-dependent signal transducer and activator of transcription 3 (show STAT3 ELISA Kits)- Rac1/Cdc42 (show CDC42 ELISA Kits)-ERK (show EPHB2 ELISA Kits) (extracellular signal-regulated kinase)-FAK (show PTK2 ELISA Kits) pathways, which enhanced neointimal formation.
SERT (show SLC6A4 ELISA Kits) protects trophoblast cells against apoptotic cell death in caspase-3 (show CASP3 ELISA Kits) independent pathway by terminating the 5-HT (show DDC ELISA Kits) signaling.
Prolonged treatment of human PMNs or mice bone marrow derived neutrophils (BMDN) with nitric oxide led to enhanced reactive oxygen species generation, caspase-8 (show CASP8 ELISA Kits)/caspase-3 (show CASP3 ELISA Kits) cleavage, reduced mitochondrial membrane potential and finally cellular apoptosis.
Induction of apoptosis in epithelial cancer cells was accompanied by a switch from glycolysis to oxidative phosphorylation, cytosol acidification and caspase-3 (show CASP3 ELISA Kits) activation.
ULK1 (show ULK1 ELISA Kits) is a novel substrate of Caspase-3 (show CASP3 ELISA Kits) and upregulation of ULK1 (show ULK1 ELISA Kits) drives autophagy initiation in leukemia cells.
These results indicate that the caspase-3 (show CASP3 ELISA Kits)/p120 RasGAP stress-sensing module impacts on carcinogen-induced liver cancer incidence but not sufficiently so as to affect overall survival.
Both the number of lung CD31 (show PECAM1 ELISA Kits)-CD45 (show PTPRC ELISA Kits)-Sca-1+ cells and the expression levels of the Shh (show SHH ELISA Kits) signaling pathway were downregulated in the lung tissues of mice with pulmonary emphysema. These cells and Shh (show SHH ELISA Kits) signaling pathway are reactivated during acute adenovirus infection.
report that mutating the caspase-3 (show CASP3 ELISA Kits) consensus site in the EAAT2 (show SLC1A2 ELISA Kits) sequence with an aspartate to asparagine mutation
These studies suggest a link between Bik (show BIK ELISA Kits)-mediated caspase (show CASP3 ELISA Kits) activation and cleavage of viral proteins.
melatonin could inhibit TLR4 (show TLR4 ELISA Kits) expression in hypoxic microglia followed by suppression of caspase3 activation leading to decrease in production of proinflammatory mediators
, lymphocyte antigen 6A-2/6E-1
, stem cell antigen 1
, SREBP cleavage activity 1
, caspase 3, apoptosis related cysteine protease
, cysteine protease CPP32
, protein Yama
, lymphocyte antigen 6 complex, locus A